iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026808

Ensembl Protein ID

AAW44230

UniProt Accession

Q5KFD4; Q5KFD4_CRYNJ

Genbank Protein ID

AAW44230.2

Protein Name

Ubiquitin-conjugating enzyme E2-28.4KD, putative

Genbank Nucleotide ID

AE017346

Gene Name

CNF02130

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNF02130	AAW44230	AAW44230

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-25	88.2	2	114

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 10   ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.eeekWspalsvesvllsiqsll 109
           +k+pp+ i a p+++ ++ +w++ i Gp+dtpYegg ++  i fp+dYPfkPP vk+ t+  ++ ++   k+C+s+   ++++W++a+sv+++l+++ s++
   Q: 2    QKSPPPFIWACPEEK-NILDWHFIIRGPPDTPYEGGEYHGLIWFPSDYPFKPPDVKLFTP--SGRFEVGHKICMSMTSyHPSTWNAAWSVATILTGLLSFM 99
           778888888888777.9******************************************9..88899999*******778********************* PP
   S: 110  aepnpesplneeaae 124
            + ++  ++ ++  e
   Q: 100  LSNEITAGAVKSTNE 114
           888888877766553 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MQKSPPPFIW ACPEEKNILD WHFIIRGPPD TPYEGGEYHG LIWFPSDYPF KPPDVKLFTP 60
SGRFEVGHKI CMSMTSYHPS TWNAAWSVAT ILTGLLSFML SNEITAGAVK STNEEKRLLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGAAGT CGCCTCCCCC ATTCATCTGG GCTTGTCCGG AGGAGAAGAA CATATTAGAT 60
TGTACGTGTC TTCACCCCTT AAGTCATTAG CGATGATTCT GACGAAAAAG ATGTAGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

cne:CNF02130

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	53.75	3.00e-24	103.00
IUUC-Aml-002152	Ailuropoda melanoleuca	52.11	5.00e-43	165.00
IUUC-Atr-003156	Amborella trichopoda	48.59	2.00e-39	153.00
IUUC-Apl-004224	Anas platyrhynchos	54.14	9.00e-42	161.00
IUUC-Aca-005049	Anolis carolinensis	50.70	6.00e-42	162.00
IUUC-Aly-005734	Arabidopsis lyrata	45.28	2.00e-37	147.00
IUUC-Ath-006640	Arabidopsis thaliana	48.57	4.00e-37	145.00
IUUC-Ago-007987	Ashbya gossypii	55.12	2.00e-43	166.00
IUUC-Acl-008060	Aspergillus clavatus	51.97	2.00e-39	154.00
IUUC-Afl-008561	Aspergillus flavus	51.97	3.00e-39	153.00
IUUC-Afu-008860	Aspergillus fumigatus	51.97	3.00e-39	153.00
IUUC-Ani-009333	Aspergillus nidulans	53.54	3.00e-40	156.00
IUUC-Ang-009810	Aspergillus niger	51.97	2.00e-39	153.00
IUUC-Aor-010127	Aspergillus oryzae	51.97	3.00e-39	153.00
IUUC-Ate-010362	Aspergillus terreus	52.76	1.00e-39	154.00
IUUC-Ame-010627	Astyanax mexicanus	51.41	7.00e-43	165.00
IUUC-Bgr-012069	Blumeria graminis	50.39	6.00e-38	149.00
IUUC-Bta-012472	Bos taurus	51.41	2.00e-42	164.00
IUUC-Bci-013843	Botrytis cinerea	51.18	3.00e-38	149.00
IUUC-Bdi-014467	Brachypodium distachyon	48.75	1.00e-41	160.00
IUUC-Bol-015471	Brassica oleracea	48.57	3.00e-37	146.00
IUUC-Bra-017777	Brassica rapa	47.86	2.00e-36	143.00
IUUC-Cel-018278	Caenorhabditis elegans	51.43	3.00e-34	135.00
IUUC-Cja-018817	Callithrix jacchus	51.18	4.00e-38	149.00
IUUC-Cfa-020885	Canis familiaris	51.41	2.00e-42	163.00
IUUC-Cpo-022326	Cavia porcellus	51.41	2.00e-42	164.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	52.17	7.00e-41	157.00
IUUC-Csa-023646	Chlorocebus sabaeus	52.11	4.00e-43	166.00
IUUC-Cho-025075	Choloepus hoffmanni	52.56	2.00e-23	99.80
IUUC-Cin-025389	Ciona intestinalis	49.30	4.00e-40	155.00
IUUC-Csv-026315	Ciona savignyi	51.88	1.00e-40	157.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	49.61	5.00e-37	145.00
IUUC-Dre-028455	Danio rerio	50.70	3.00e-42	163.00
IUUC-Dno-029667	Dasypus novemcinctus	52.82	6.00e-43	165.00
IUUC-Dor-030747	Dipodomys ordii	44.96	1.00e-31	127.00
IUUC-Dse-031231	Dothistroma septosporum	51.97	2.00e-38	150.00
IUUC-Dme-031841	Drosophila melanogaster	46.48	4.00e-41	159.00
IUUC-Ete-032258	Echinops telfairi	44.94	1.00e-37	148.00
IUUC-Eeu-034443	Erinaceus europaeus	51.40	3.00e-30	122.00
IUUC-Fca-036167	Felis catus	47.22	2.00e-33	133.00
IUUC-Fal-037114	Ficedula albicollis	54.14	1.00e-41	160.00
IUUC-Fox-037957	Fusarium oxysporum	54.13	1.00e-34	137.00
IUUC-Fso-038277	Fusarium solani	52.76	8.00e-39	151.00
IUUC-Gmo-039501	Gadus morhua	50.70	2.00e-42	163.00
IUUC-Ggr-040010	Gaeumannomyces graminis	51.97	2.00e-38	150.00
IUUC-Gga-041257	Gallus gallus	54.14	5.00e-42	162.00
IUUC-Gac-041433	Gasterosteus aculeatus	51.41	4.00e-43	166.00
IUUC-Gma-044091	Glycine max	47.86	1.00e-37	147.00
IUUC-Ggo-044437	Gorilla gorilla	51.18	2.00e-37	147.00
IUUC-Hsa-046693	Homo sapiens	52.11	6.00e-43	165.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	51.41	2.00e-42	163.00
IUUC-Kpa-049391	Komagataella pastoris	53.54	5.00e-38	149.00
IUUC-Lch-049617	Latimeria chalumnae	53.38	9.00e-42	161.00
IUUC-Lpe-050949	Leersia perrieri	52.45	1.00e-40	157.00
IUUC-Loc-052157	Lepisosteus oculatus	51.41	8.00e-43	165.00
IUUC-Lma-053128	Leptosphaeria maculans	54.33	4.00e-41	159.00
IUUC-Laf-054455	Loxodonta africana	50.70	4.00e-42	162.00
IUUC-Mcc-054756	Macaca mulatta	52.11	4.00e-43	166.00
IUUC-Meu-056106	Macropus eugenii	51.40	3.00e-30	123.00
IUUC-Mor-057202	Magnaporthe oryzae	50.39	3.00e-37	146.00
IUUC-Mpo-057349	Magnaporthe poae	51.18	9.00e-38	148.00
IUUC-Mtr-058271	Medicago truncatula	47.86	2.00e-34	137.00
IUUC-Mla-058894	Melampsora laricipopulina	63.08	1.00e-50	189.00
IUUC-Mga-059493	Meleagris gallopavo	54.14	5.00e-42	162.00
IUUC-Mvi-060232	Microbotryum violaceum	57.41	2.00e-52	196.00
IUUC-Mmr-060957	Microcebus murinus	52.82	3.00e-43	166.00
IUUC-Mdo-062141	Monodelphis domestica	51.41	1.00e-42	164.00
IUUC-Mmu-063882	Mus musculus	50.70	5.00e-42	162.00
IUUC-Mac-064530	Musa acuminata	51.05	7.00e-41	158.00
IUUC-Mpu-065902	Mustela putorius furo	52.11	6.00e-43	165.00
IUUC-Mlu-068008	Myotis lucifugus	50.70	1.00e-40	157.00
IUUC-Nfi-068515	Neosartorya fischeri	51.97	2.00e-39	153.00
IUUC-Ncr-068755	Neurospora crassa	49.61	3.00e-36	143.00
IUUC-Opr-071201	Ochotona princeps	47.20	3.00e-30	122.00
IUUC-Ont-071311	Oreochromis niloticus	51.41	5.00e-43	166.00
IUUC-Oan-073310	Ornithorhynchus anatinus	52.11	1.00e-42	164.00
IUUC-Ocu-074514	Oryctolagus cuniculus	51.41	2.00e-42	163.00
IUUC-Oba-075200	Oryza barthii	52.45	1.00e-40	157.00
IUUC-Obr-076396	Oryza brachyantha	51.75	1.00e-40	157.00
IUUC-Ogl-077398	Oryza glaberrima	52.45	1.00e-40	157.00
IUUC-Ogu-078362	Oryza glumaepatula	52.45	1.00e-40	157.00
IUUC-Oin-079625	Oryza indica	52.45	1.00e-40	157.00
IUUC-Ome-081187	Oryza meridionalis	52.45	8.00e-41	158.00
IUUC-Oni-082271	Oryza nivara	52.45	1.00e-40	157.00
IUUC-Opu-083487	Oryza punctata	52.45	1.00e-40	157.00
IUUC-Oru-085263	Oryza rufipogon	52.45	1.00e-40	157.00
IUUC-Osa-085694	Oryza sativa	52.45	1.00e-40	157.00
IUUC-Ola-086450	Oryzias latipes	51.41	4.00e-43	166.00
IUUC-Olu-087733	Ostreococcus lucimarinus	44.36	4.00e-27	112.00
IUUC-Oga-088054	Otolemur garnettii	46.84	9.00e-39	151.00
IUUC-Oar-089486	Ovis aries	51.41	2.00e-42	164.00
IUUC-Pan-092633	Papio anubis	52.11	4.00e-43	166.00
IUUC-Pno-095025	Phaeosphaeria nodorum	51.97	4.00e-41	159.00
IUUC-Ppa-095641	Physcomitrella patens	50.00	1.00e-40	157.00
IUUC-Pfo-096423	Poecilia formosa	53.38	5.00e-42	162.00
IUUC-Pab-097771	Pongo abelii	52.11	4.00e-43	166.00
IUUC-Pop-099714	Populus trichocarpa	45.86	5.00e-38	149.00
IUUC-Pca-100493	Procavia capensis	41.32	3.00e-24	103.00
IUUC-Ppe-102054	Prunus persica	49.29	1.00e-37	147.00
IUUC-Pva-102224	Pteropus vampyrus	52.11	7.00e-43	165.00
IUUC-Pgr-103332	Puccinia graminis	55.49	4.00e-53	199.00
IUUC-Ptt-103776	Puccinia triticina	58.82	2.00e-53	200.00
IUUC-Pte-104166	Pyrenophora teres	51.97	8.00e-41	158.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	51.97	8.00e-41	158.00
IUUC-Rno-105593	Rattus norvegicus	50.70	5.00e-42	162.00
IUUC-Sce-106212	Saccharomyces cerevisiae	51.77	9.00e-46	174.00
IUUC-Sha-106767	Sarcophilus harrisii	50.70	3.00e-42	163.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	48.25	5.00e-41	158.00
IUUC-Spo-108094	Schizosaccharomyces pombe	49.65	1.00e-42	163.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	49.61	2.00e-37	146.00
IUUC-Smo-108965	Selaginella moellendorffii	49.64	5.00e-40	155.00
IUUC-Sit-110407	Setaria italica	51.05	4.00e-40	155.00
IUUC-Sly-111642	Solanum lycopersicum	49.29	2.00e-33	133.00
IUUC-Stu-112336	Solanum tuberosum	48.57	3.00e-34	136.00
IUUC-Sbi-114327	Sorghum bicolor	51.05	3.00e-40	156.00
IUUC-Sre-115170	Sporisorium reilianum	57.24	1.00e-45	174.00
IUUC-Ssc-116385	Sus scrofa	51.41	1.00e-42	164.00
IUUC-Tgu-117041	Taeniopygia guttata	54.14	8.00e-42	161.00
IUUC-Tru-117697	Takifugu rubripes	51.41	4.00e-43	166.00
IUUC-Tsy-119024	Tarsius syrichta	49.61	8.00e-35	138.00
IUUC-Tni-120466	Tetraodon nigroviridis	51.03	4.00e-42	162.00
IUUC-Tca-121569	Theobroma cacao	48.59	8.00e-37	144.00
IUUC-Tre-121882	Trichoderma reesei	50.39	5.00e-38	149.00
IUUC-Tvi-122466	Trichoderma virens	50.39	4.00e-38	149.00
IUUC-Tae-124797	Triticum aestivum	51.75	5.00e-40	155.00
IUUC-Tur-126536	Triticum urartu	53.44	1.00e-39	154.00
IUUC-Tme-127051	Tuber melanosporum	51.18	2.00e-40	157.00
IUUC-Ttr-128466	Tursiops truncatus	51.41	2.00e-42	164.00
IUUC-Uma-129383	Ustilago maydis	57.24	2.00e-45	173.00
IUUC-Vda-130013	Verticillium dahliae	51.97	7.00e-38	148.00
IUUC-Vvi-131251	Vitis vinifera	47.86	2.00e-34	137.00
IUUC-Xtr-132408	Xenopus tropicalis	51.41	2.00e-42	163.00
IUUC-Xma-133893	Xiphophorus maculatus	53.38	4.00e-42	162.00
IUUC-Yli-134618	Yarrowia lipolytica	56.72	7.00e-46	174.00
IUUC-Zma-135216	Zea mays	49.65	9.00e-40	154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence