iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087346

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04073990

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000015903.1	ENSORLT00000019913.1	ENSORLP00000019912.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.70e-87	292.8	299	628

Active Site

Position(s)	Description	Evidence
597	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrlldl 90
           ++++v+fvgE++ d+gG  +e +a++++elqn+ ++l+  ++n++ +   n+d +l np      h+ +F+flG+llg+a+++g +l l
   Q: 299  RVWKVKFVGESVDDCGGGYSESIAEMCEELQNSLTPLLIVTPNGRDESGANRDCFLLNPaakspLHMGMFRFLGVLLGIAIRTGSPLSL 387
           4566****************************************9999*******999999999************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
           +l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e ++++l f+     +++++ +++  +++  ++t eN+ eYv+l ++
   Q: 388  NLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMTLPFT-----VPNASGQDIQLSSKYSHITLENRAEYVRLAIN 471
           *************************************999999999*****9.....7889999999********************** PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           yrl+e ++eqv a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ p iqwFwev+e+fs++er+ fL+Fv
   Q: 472  YRLHE-FDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-VEPTAPLIQWFWEVMESFSNTERSLFLRFV 558
           *****.**************************************************77.****************************** PP
   S: 269  TgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +g+ rlP + +a+++ r fv++     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 559  WGRTRLP-RTIADFRGRDFVVQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 628
           *******.8*************999988888***********************************99875 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

WGDGDYGKLG RGGSDGCKVP MKIDSLTGLG VVKVECGSQF SVALTKSGAV YTWGKGDYHR 60
LGHGSDDHVR RPRQVQGLQG KKVIAIATGS LHCVCCTEDG EVYTWGDNDE GQLGDGTTNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGGAGACG GAGACTACGG CAAGCTGGGC CGAGGAGGCA GCGATGGCTG CAAAGTCCCC 60
ATGAAGGTAA AGCAGATTAG CCGAAAGAAA CAAACTACTT TGTCAAATAA GGTGGGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002112	Ailuropoda melanoleuca	92.55	0.00e+00	1194.00
IUUC-Apl-003983	Anas platyrhynchos	94.28	0.00e+00	1210.00
IUUC-Aca-004300	Anolis carolinensis	94.12	0.00e+00	1208.00
IUUC-Ame-010621	Astyanax mexicanus	94.44	0.00e+00	1211.00
IUUC-Bta-013067	Bos taurus	92.55	0.00e+00	1195.00
IUUC-Cja-019687	Callithrix jacchus	92.23	0.00e+00	1186.00
IUUC-Cfa-020672	Canis familiaris	92.55	0.00e+00	1195.00
IUUC-Cpo-021819	Cavia porcellus	92.42	0.00e+00	1194.00
IUUC-Csa-023817	Chlorocebus sabaeus	92.23	0.00e+00	1190.00
IUUC-Cin-025709	Ciona intestinalis	63.17	0.00e+00	837.00
IUUC-Csv-026336	Ciona savignyi	64.62	0.00e+00	851.00
IUUC-Dre-027717	Danio rerio	93.48	0.00e+00	1201.00
IUUC-Dno-029296	Dasypus novemcinctus	91.41	0.00e+00	1181.00
IUUC-Dor-030979	Dipodomys ordii	91.19	0.00e+00	1015.00
IUUC-Dme-032171	Drosophila melanogaster	67.50	0.00e+00	864.00
IUUC-Eca-034046	Equus caballus	92.23	0.00e+00	1191.00
IUUC-Eeu-034859	Erinaceus europaeus	92.06	3.00e-149	524.00
IUUC-Fca-036262	Felis catus	92.71	0.00e+00	1199.00
IUUC-Fal-037562	Ficedula albicollis	94.44	0.00e+00	1212.00
IUUC-Gmo-038739	Gadus morhua	91.33	0.00e+00	1031.00
IUUC-Gga-040359	Gallus gallus	94.12	0.00e+00	1207.00
IUUC-Gac-041879	Gasterosteus aculeatus	92.21	0.00e+00	1043.00
IUUC-Ggo-044692	Gorilla gorilla	91.76	0.00e+00	1180.00
IUUC-Hsa-045995	Homo sapiens	92.39	0.00e+00	1192.00
IUUC-Lch-049808	Latimeria chalumnae	93.82	0.00e+00	1202.00
IUUC-Loc-052685	Lepisosteus oculatus	94.61	0.00e+00	1212.00
IUUC-Laf-053372	Loxodonta africana	91.93	0.00e+00	1191.00
IUUC-Mcc-054693	Macaca mulatta	92.08	0.00e+00	1190.00
IUUC-Meu-056660	Macropus eugenii	92.37	0.00e+00	1177.00
IUUC-Mga-059371	Meleagris gallopavo	93.98	0.00e+00	1204.00
IUUC-Mmr-060787	Microcebus murinus	92.39	0.00e+00	1191.00
IUUC-Mdo-062518	Monodelphis domestica	94.28	0.00e+00	1209.00
IUUC-Mmu-063690	Mus musculus	92.37	0.00e+00	1191.00
IUUC-Mpu-066478	Mustela putorius furo	92.55	0.00e+00	1196.00
IUUC-Opr-070990	Ochotona princeps	92.71	0.00e+00	1191.00
IUUC-Ont-072285	Oreochromis niloticus	95.36	0.00e+00	1218.00
IUUC-Oan-072721	Ornithorhynchus anatinus	92.08	0.00e+00	1182.00
IUUC-Ocu-074273	Oryctolagus cuniculus	92.56	0.00e+00	1193.00
IUUC-Oga-088742	Otolemur garnettii	92.23	0.00e+00	1188.00
IUUC-Oar-090093	Ovis aries	92.55	0.00e+00	1196.00
IUUC-Ptr-091034	Pan troglodytes	92.39	0.00e+00	1193.00
IUUC-Pan-092783	Papio anubis	92.39	0.00e+00	1191.00
IUUC-Psi-094027	Pelodiscus sinensis	93.81	0.00e+00	1201.00
IUUC-Pfo-097354	Poecilia formosa	93.44	0.00e+00	1053.00
IUUC-Pva-103147	Pteropus vampyrus	86.69	0.00e+00	847.00
IUUC-Rno-105458	Rattus norvegicus	92.37	0.00e+00	1191.00
IUUC-Sha-106959	Sarcophilus harrisii	79.94	0.00e+00	986.00
IUUC-Sar-113532	Sorex araneus	78.26	2.00e-110	395.00
IUUC-Ssc-116304	Sus scrofa	93.47	0.00e+00	900.00
IUUC-Tgu-116789	Taeniopygia guttata	93.98	0.00e+00	1205.00
IUUC-Tru-118129	Takifugu rubripes	95.52	0.00e+00	1218.00
IUUC-Tsy-119302	Tarsius syrichta	79.63	2.00e-62	236.00
IUUC-Tni-120374	Tetraodon nigroviridis	95.36	0.00e+00	1216.00
IUUC-Tbe-128137	Tupaia belangeri	90.58	0.00e+00	761.00
IUUC-Ttr-128273	Tursiops truncatus	92.08	0.00e+00	1188.00
IUUC-Xtr-132185	Xenopus tropicalis	90.94	0.00e+00	1173.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence