iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gmo-038872

Ensembl Protein ID

ENSGMOP00000015968.1

UniProt Accession

U5ILH7; U5ILH7_GADMO

Genbank Protein ID

AGE12621.1

Protein Name

Estrogen receptor alpha

Genbank Nucleotide ID

JX178935

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGMOG00000014898.1	ENSGMOT00000016376.1	ENSGMOP00000015968.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UMI	57.51	8.00e-111	398.00	IUUC-Hsa-046944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gadus morhua

Protein Sequence
(Fasta)

LDPHGPPSDA SLQSLGSGST SPLVFVPSSP QLSPYLPPPG SPYLEAPATP GYRSSMGSGP 60
QHSLSREDLC DTIEGSSRLV GSGVSAVGTV FELAKETRYC AVCSDYASGY HYGVWSCEGC 120

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Nucleotide Sequence
(Fasta)

CTGGACCCCC ATGGCGGGCC CCCCCTCGGA CGCCAGCCTG CAGTCCCTGG GCAGTGGGTC 60
CACCAGCCCC CTGGTGTTTG TGCCCAGCAG CCCCCAGCTC AGCCCCTACC TGCACCCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR024178--Oest_rcpt/oest-rel_rcp
IPR001292--Oestr_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF02159--Oest_recep
PF00105--zf-C4

PRINTS

PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005634--C:nucleus
GO:0030284--F:estrogen receptor activity
GO:0043565--F:sequence-specific DNA binding
GO:0005496--F:steroid binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001925	Ailuropoda melanoleuca	56.31	1.00e-113	402.00
IUUC-Apl-003688	Anas platyrhynchos	52.60	3.00e-109	388.00
IUUC-Aca-005222	Anolis carolinensis	51.26	2.00e-114	406.00
IUUC-Ame-010731	Astyanax mexicanus	65.82	1.00e-147	516.00
IUUC-Bta-013112	Bos taurus	56.86	2.00e-114	405.00
IUUC-Cja-019408	Callithrix jacchus	53.39	9.00e-115	407.00
IUUC-Cfa-020694	Canis familiaris	54.36	9.00e-115	407.00
IUUC-Cpo-021426	Cavia porcellus	53.14	4.00e-112	398.00
IUUC-Csa-023736	Chlorocebus sabaeus	54.26	4.00e-118	417.00
IUUC-Dre-027698	Danio rerio	63.03	4.00e-145	508.00
IUUC-Dno-029477	Dasypus novemcinctus	57.72	2.00e-113	402.00
IUUC-Dor-030572	Dipodomys ordii	57.47	5.00e-112	397.00
IUUC-Ete-032849	Echinops telfairi	57.02	8.00e-87	314.00
IUUC-Eca-033605	Equus caballus	53.01	3.00e-116	411.00
IUUC-Eeu-034683	Erinaceus europaeus	48.34	4.00e-40	158.00
IUUC-Fca-035928	Felis catus	58.00	3.00e-113	401.00
IUUC-Fal-036754	Ficedula albicollis	52.31	2.00e-119	422.00
IUUC-Gga-040988	Gallus gallus	52.70	9.00e-118	417.00
IUUC-Gac-042015	Gasterosteus aculeatus	75.97	3.00e-161	561.00
IUUC-Ggo-044749	Gorilla gorilla	52.28	4.00e-115	408.00
IUUC-Hsa-046944	Homo sapiens	52.28	2.00e-115	409.00
IUUC-Itr-048863	Ictidomys tridecemlineatus	58.29	8.00e-113	400.00
IUUC-Loc-052414	Lepisosteus oculatus	62.47	1.00e-159	556.00
IUUC-Mcc-054781	Macaca mulatta	52.28	4.00e-115	408.00
IUUC-Meu-056232	Macropus eugenii	54.20	7.00e-112	397.00
IUUC-Mga-059319	Meleagris gallopavo	52.70	1.00e-117	417.00
IUUC-Mmr-061636	Microcebus murinus	47.44	5.00e-40	158.00
IUUC-Mdo-062661	Monodelphis domestica	59.03	1.00e-114	407.00
IUUC-Mmu-063330	Mus musculus	57.22	3.00e-113	402.00
IUUC-Mpu-065757	Mustela putorius furo	60.16	2.00e-115	409.00
IUUC-Mlu-067712	Myotis lucifugus	57.67	8.00e-115	407.00
IUUC-Nle-069283	Nomascus leucogenys	53.74	3.00e-115	408.00
IUUC-Opr-070391	Ochotona princeps	57.47	5.00e-119	421.00
IUUC-Ont-071369	Oreochromis niloticus	72.15	3.00e-151	528.00
IUUC-Oan-073734	Ornithorhynchus anatinus	45.67	4.00e-60	224.00
IUUC-Ocu-074292	Oryctolagus cuniculus	57.71	2.00e-116	412.00
IUUC-Ola-087052	Oryzias latipes	70.79	1.00e-158	553.00
IUUC-Oga-088586	Otolemur garnettii	53.60	4.00e-113	401.00
IUUC-Oar-090156	Ovis aries	52.17	1.00e-118	419.00
IUUC-Ptr-091321	Pan troglodytes	52.28	4.00e-115	408.00
IUUC-Pan-092851	Papio anubis	52.28	3.00e-115	408.00
IUUC-Psi-093434	Pelodiscus sinensis	54.42	1.00e-124	439.00
IUUC-Pfo-097379	Poecilia formosa	72.92	1.00e-168	586.00
IUUC-Pab-097735	Pongo abelii	52.28	3.00e-115	408.00
IUUC-Pva-102125	Pteropus vampyrus	57.11	3.00e-112	399.00
IUUC-Rno-106121	Rattus norvegicus	57.00	2.00e-113	402.00
IUUC-Sha-107547	Sarcophilus harrisii	55.63	1.00e-114	407.00
IUUC-Sar-113650	Sorex araneus	45.69	4.00e-59	221.00
IUUC-Tgu-117175	Taeniopygia guttata	52.10	2.00e-119	422.00
IUUC-Tru-117545	Takifugu rubripes	69.85	6.00e-174	604.00
IUUC-Tsy-119586	Tarsius syrichta	47.10	4.00e-95	342.00
IUUC-Tni-120121	Tetraodon nigroviridis	68.83	5.00e-174	603.00
IUUC-Tbe-127548	Tupaia belangeri	50.66	2.00e-86	313.00
IUUC-Ttr-128374	Tursiops truncatus	54.11	9.00e-101	360.00
IUUC-Vpa-130464	Vicugna pacos	46.01	3.00e-66	245.00
IUUC-Xtr-132171	Xenopus tropicalis	52.01	2.00e-111	396.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence