iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-001124

Ensembl Protein ID

EMT01689

UniProt Accession

R7VZF3; R7VZF3_AEGTA

Genbank Protein ID

EMT01689.1

Protein Name

NEDD8-activating enzyme E1 catalytic subunit

Genbank Nucleotide ID

KD644086

Gene Name

F775_29991

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_29991	EMT01689	EMT01689

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.20e-71	242.0	1	157

Active Site

Position(s)	Description	Evidence
138	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 50   mdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclna.............rvpl 137
           mdt++vsnlnrqFLfr +dvgk+KAevaa+++ e+++ vn+++h ++i+++e e  F+++f+++vl+ld++ear ++n++ +                +p+
   Q: 1    MDTIDVSNLNRQFLFRIQDVGKPKAEVAAKRVMERVSGVNIVPHFCRIEDKELE--FYNQFQIIVLGLDSIEARSYINSVACGFleydsddrpvqetVKPM 99
           89*************************************************999..****************************************99*** PP
   S: 138  iesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewavlf 193
           +++gt+G++G++rvii+g+t c +c+    ppq+++P+ctl+etp++a h+ie+a+l+
   Q: 100  VDGGTEGFKGHARVIIPGMTPCFECNIwlFPPQVKFPLCTLAETPRTAAHCIEYAHLI 157
           *******************************************************444 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MDTIDVSNLN RQFLFRIQDV GKPKAEVAAK RVMERVSGVN IVPHFCRIED KELEFYNQFQ 60
IIVLGLDSIE ARSYINSVAC GFLEYDSDDR PVQETVKPMV DGGTEGFKGH ARVIIPGMTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACACCA TCGACGTCTC CAACCTCAAC CGCCAGTTCC TCTTCAGGTC CTTTTTGACA 60
CCCAGTCCTT CTGATTATAC ACAAGAATAG GGTTTATGCA GTATAGTGGT ATTAAACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

ats:F775_29991

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001578	Ailuropoda melanoleuca	48.22	3.00e-88	318.00
IUUC-Atr-002591	Amborella trichopoda	76.34	1.00e-165	575.00
IUUC-Apl-003671	Anas platyrhynchos	48.82	4.00e-89	321.00
IUUC-Aca-004749	Anolis carolinensis	48.22	2.00e-88	319.00
IUUC-Aly-005747	Arabidopsis lyrata	73.66	2.00e-157	547.00
IUUC-Ath-006623	Arabidopsis thaliana	73.46	5.00e-156	543.00
IUUC-Ago-007934	Ashbya gossypii	36.27	6.00e-44	170.00
IUUC-Acl-008047	Aspergillus clavatus	48.80	8.00e-92	329.00
IUUC-Afl-008615	Aspergillus flavus	41.16	3.00e-57	214.00
IUUC-Afu-008996	Aspergillus fumigatus	49.70	1.00e-84	306.00
IUUC-Ani-009281	Aspergillus nidulans	48.75	2.00e-71	262.00
IUUC-Ang-009539	Aspergillus niger	49.10	4.00e-82	297.00
IUUC-Aor-010151	Aspergillus oryzae	48.04	4.00e-79	287.00
IUUC-Ate-010502	Aspergillus terreus	50.30	5.00e-82	297.00
IUUC-Ame-011837	Astyanax mexicanus	47.34	2.00e-79	288.00
IUUC-Bgr-012068	Blumeria graminis	50.90	1.00e-84	306.00
IUUC-Bta-013003	Bos taurus	48.82	2.00e-89	322.00
IUUC-Bci-013983	Botrytis cinerea	52.40	2.00e-84	305.00
IUUC-Bdi-014429	Brachypodium distachyon	94.41	0.00e+00	708.00
IUUC-Bol-015813	Brassica oleracea	77.42	4.00e-165	573.00
IUUC-Bra-018023	Brassica rapa	76.34	1.00e-162	565.00
IUUC-Cel-018684	Caenorhabditis elegans	48.97	2.00e-87	315.00
IUUC-Cja-019200	Callithrix jacchus	48.82	9.00e-87	313.00
IUUC-Cfa-021038	Canis familiaris	48.82	3.00e-89	321.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	58.02	2.00e-116	411.00
IUUC-Csa-024079	Chlorocebus sabaeus	48.52	3.00e-89	321.00
IUUC-Cho-025052	Choloepus hoffmanni	41.76	1.00e-70	259.00
IUUC-Cin-025113	Ciona intestinalis	48.82	7.00e-81	293.00
IUUC-Csv-026231	Ciona savignyi	48.24	3.00e-86	311.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	50.15	1.00e-83	302.00
IUUC-Cne-026850	Cryptococcus neoformans	46.55	5.00e-76	277.00
IUUC-Cme-027275	Cyanidioschyzon merolae	37.20	9.00e-62	229.00
IUUC-Dre-028751	Danio rerio	47.51	3.00e-79	288.00
IUUC-Dno-029571	Dasypus novemcinctus	48.52	5.00e-88	317.00
IUUC-Dor-030395	Dipodomys ordii	49.70	1.00e-89	323.00
IUUC-Dse-031329	Dothistroma septosporum	45.00	7.00e-77	280.00
IUUC-Dme-031776	Drosophila melanogaster	47.93	3.00e-82	298.00
IUUC-Ete-032894	Echinops telfairi	44.70	8.00e-27	114.00
IUUC-Eca-034389	Equus caballus	48.82	2.00e-89	321.00
IUUC-Eeu-035152	Erinaceus europaeus	42.69	2.00e-67	249.00
IUUC-Fca-036032	Felis catus	48.82	3.00e-89	321.00
IUUC-Fal-037506	Ficedula albicollis	49.11	4.00e-90	324.00
IUUC-Fox-037871	Fusarium oxysporum	50.75	4.00e-83	300.00
IUUC-Fso-038350	Fusarium solani	50.75	6.00e-83	300.00
IUUC-Gmo-039647	Gadus morhua	47.65	2.00e-80	292.00
IUUC-Ggr-039859	Gaeumannomyces graminis	49.55	2.00e-81	295.00
IUUC-Gga-040843	Gallus gallus	47.63	3.00e-83	301.00
IUUC-Gac-042601	Gasterosteus aculeatus	48.07	6.00e-80	290.00
IUUC-Gma-042744	Glycine max	75.27	7.00e-163	565.00
IUUC-Ggo-044788	Gorilla gorilla	48.67	5.00e-88	317.00
IUUC-Hsa-045849	Homo sapiens	48.82	2.00e-89	322.00
IUUC-Hvu-047819	Hordeum vulgare	98.58	1.00e-157	548.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	48.82	9.00e-89	320.00
IUUC-Kpa-049393	Komagataella pastoris	51.50	2.00e-71	261.00
IUUC-Lch-049471	Latimeria chalumnae	46.72	9.00e-81	293.00
IUUC-Lpe-051297	Leersia perrieri	90.13	0.00e+00	715.00
IUUC-Loc-052910	Lepisosteus oculatus	48.22	3.00e-80	291.00
IUUC-Lma-053181	Leptosphaeria maculans	48.97	3.00e-83	301.00
IUUC-Laf-054314	Loxodonta africana	46.78	4.00e-87	314.00
IUUC-Mcc-054870	Macaca mulatta	48.82	2.00e-89	322.00
IUUC-Meu-056574	Macropus eugenii	39.64	1.00e-42	166.00
IUUC-Mor-056919	Magnaporthe oryzae	46.99	1.00e-82	299.00
IUUC-Mpo-057614	Magnaporthe poae	48.95	8.00e-76	276.00
IUUC-Mtr-058110	Medicago truncatula	76.34	3.00e-166	577.00
IUUC-Mla-058949	Melampsora laricipopulina	44.71	5.00e-73	267.00
IUUC-Mga-059455	Meleagris gallopavo	49.11	3.00e-89	321.00
IUUC-Mvi-060270	Microbotryum violaceum	45.01	6.00e-80	290.00
IUUC-Mmr-061155	Microcebus murinus	49.41	5.00e-90	323.00
IUUC-Mdo-062037	Monodelphis domestica	48.22	9.00e-88	316.00
IUUC-Mmu-063670	Mus musculus	48.82	3.00e-89	321.00
IUUC-Mac-064711	Musa acuminata	79.55	3.00e-164	570.00
IUUC-Mpu-066734	Mustela putorius furo	48.82	2.00e-89	322.00
IUUC-Mlu-067068	Myotis lucifugus	49.11	1.00e-89	323.00
IUUC-Nfi-068349	Neosartorya fischeri	49.70	9.00e-85	306.00
IUUC-Ncr-068626	Neurospora crassa	50.46	4.00e-79	287.00
IUUC-Nle-069366	Nomascus leucogenys	50.52	3.00e-82	298.00
IUUC-Ont-072196	Oreochromis niloticus	47.35	4.00e-78	284.00
IUUC-Oan-073511	Ornithorhynchus anatinus	48.07	1.00e-87	316.00
IUUC-Ocu-073773	Oryctolagus cuniculus	49.11	2.00e-89	322.00
IUUC-Oba-075726	Oryza barthii	80.05	0.00e+00	639.00
IUUC-Obr-076286	Oryza brachyantha	88.74	0.00e+00	702.00
IUUC-Ogu-078473	Oryza glumaepatula	80.05	0.00e+00	640.00
IUUC-Oin-079393	Oryza indica	89.01	0.00e+00	707.00
IUUC-Olo-080446	Oryza longistaminata	84.18	0.00e+00	652.00
IUUC-Ome-081737	Oryza meridionalis	84.37	0.00e+00	651.00
IUUC-Oni-082853	Oryza nivara	80.05	0.00e+00	639.00
IUUC-Opu-083590	Oryza punctata	88.20	0.00e+00	701.00
IUUC-Oru-084184	Oryza rufipogon	80.05	0.00e+00	639.00
IUUC-Osa-085402	Oryza sativa	89.01	0.00e+00	707.00
IUUC-Ola-086615	Oryzias latipes	48.82	1.00e-79	289.00
IUUC-Olu-087738	Ostreococcus lucimarinus	56.99	1.00e-111	395.00
IUUC-Oga-088101	Otolemur garnettii	48.82	2.00e-89	322.00
IUUC-Oar-090293	Ovis aries	48.10	2.00e-87	315.00
IUUC-Ptr-090503	Pan troglodytes	48.82	2.00e-89	322.00
IUUC-Pan-092477	Papio anubis	47.90	9.00e-85	306.00
IUUC-Psi-093442	Pelodiscus sinensis	49.70	2.00e-91	328.00
IUUC-Pma-094247	Petromyzon marinus	48.69	3.00e-79	288.00
IUUC-Pno-094780	Phaeosphaeria nodorum	48.38	1.00e-90	325.00
IUUC-Ppa-095961	Physcomitrella patens	62.10	1.00e-134	472.00
IUUC-Pfo-096846	Poecilia formosa	49.10	3.00e-81	295.00
IUUC-Pab-098060	Pongo abelii	48.52	6.00e-81	294.00
IUUC-Pop-099914	Populus trichocarpa	78.71	1.00e-168	585.00
IUUC-Pca-100500	Procavia capensis	42.51	2.00e-70	259.00
IUUC-Ppe-102008	Prunus persica	78.49	6.00e-170	589.00
IUUC-Pva-103095	Pteropus vampyrus	59.85	4.00e-42	164.00
IUUC-Pgr-103666	Puccinia graminis	45.18	2.00e-78	285.00
IUUC-Ptt-103901	Puccinia triticina	45.18	3.00e-77	281.00
IUUC-Pte-104198	Pyrenophora teres	48.38	3.00e-82	298.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.08	9.00e-81	293.00
IUUC-Rno-105446	Rattus norvegicus	48.82	3.00e-89	321.00
IUUC-Sce-106355	Saccharomyces cerevisiae	36.53	4.00e-46	177.00
IUUC-Sha-106664	Sarcophilus harrisii	47.34	4.00e-86	311.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	39.77	2.00e-71	262.00
IUUC-Spo-108345	Schizosaccharomyces pombe	38.24	7.00e-70	257.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	49.10	3.00e-72	265.00
IUUC-Smo-109098	Selaginella moellendorffii	60.11	1.00e-135	475.00
IUUC-Sit-109724	Setaria italica	92.82	0.00e+00	693.00
IUUC-Sly-110916	Solanum lycopersicum	76.82	2.00e-165	574.00
IUUC-Stu-112236	Solanum tuberosum	77.09	8.00e-166	575.00
IUUC-Sar-113044	Sorex araneus	48.22	8.00e-88	316.00
IUUC-Sbi-114276	Sorghum bicolor	91.22	0.00e+00	691.00
IUUC-Sre-114963	Sporisorium reilianum	47.29	2.00e-80	292.00
IUUC-Ssc-116301	Sus scrofa	48.10	3.00e-87	314.00
IUUC-Tgu-117265	Taeniopygia guttata	49.11	6.00e-90	323.00
IUUC-Tru-117526	Takifugu rubripes	48.97	2.00e-80	292.00
IUUC-Tsy-119483	Tarsius syrichta	48.82	3.00e-89	321.00
IUUC-Tni-120363	Tetraodon nigroviridis	49.12	2.00e-82	298.00
IUUC-Tca-121731	Theobroma cacao	77.09	4.00e-170	590.00
IUUC-Tre-122221	Trichoderma reesei	50.45	7.00e-83	300.00
IUUC-Tvi-122352	Trichoderma virens	49.55	8.00e-82	296.00
IUUC-Tae-123864	Triticum aestivum	100.00	0.00e+00	748.00
IUUC-Tur-126070	Triticum urartu	98.89	0.00e+00	711.00
IUUC-Tme-127199	Tuber melanosporum	51.06	1.00e-87	316.00
IUUC-Tbe-128076	Tupaia belangeri	48.52	1.00e-88	319.00
IUUC-Uma-129638	Ustilago maydis	47.88	5.00e-79	287.00
IUUC-Vda-129963	Verticillium dahliae	48.93	1.00e-77	283.00
IUUC-Vpa-130637	Vicugna pacos	41.72	8.00e-67	246.00
IUUC-Vvi-131613	Vitis vinifera	78.76	7.00e-172	595.00
IUUC-Xtr-132924	Xenopus tropicalis	47.73	6.00e-78	283.00
IUUC-Xma-134209	Xiphophorus maculatus	48.82	9.00e-82	296.00
IUUC-Yli-134365	Yarrowia lipolytica	49.85	1.00e-81	296.00
IUUC-Zma-135941	Zea mays	81.34	0.00e+00	658.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence