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Tag Content
iUUCD ID IUUC-Bta-012522
Ensembl Protein ID ENSBTAP00000010497.4
UniProt Accession F1MMY4; F1MMY4_BOVIN
Genbank Protein ID ENSBTAP00000010497
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID DAAA02018575
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000007986.5 ENSBTAT00000010497.4 ENSBTAP00000010497.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 4.10e-14 52.6 836 876
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 836  WCFVCSKGGS----LLCCESCPAAFHPDCLSIE----MPDGS-WFCNDCR 876
           8*********....*******************....9***8.******8 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
LFLTLQCSET EAPRLMKCVK MKQAPEVLGS ANGKTPSCDV SRECSVFLSK AQLSAGLQDG 60
VVQKFNGHDA LPFIPAERLK DLTSRVFNGE PGAHDAKLRF ESQEVKGLGT PPHTTPVKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012522|E3,PHD|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTTTTCTAA CGCTGCAGTG TTCTGAGACG GAGGCACCTA GGCTGAATGG AATTCAGCGT 60
CAGGAAAAGC CCTCTTTCTG CTCCAAAGGT GGTGAAGTGC GTGAAGATGA AGCAGGCCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012522|E3,PHD|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 87.66 0.00e+00 2325.00
IUUC-Apl-003677 Anas platyrhynchos 77.00 0.00e+00 2034.00
IUUC-Aca-004278 Anolis carolinensis 74.86 0.00e+00 1379.00
IUUC-Ame-011932 Astyanax mexicanus 70.81 0.00e+00 1025.00
IUUC-Cja-018908 Callithrix jacchus 85.72 0.00e+00 2226.00
IUUC-Cfa-020894 Canis familiaris 86.57 0.00e+00 2363.00
IUUC-Cpo-021982 Cavia porcellus 84.11 0.00e+00 2237.00
IUUC-Csa-023807 Chlorocebus sabaeus 86.33 0.00e+00 2259.00
IUUC-Cho-024405 Choloepus hoffmanni 72.55 0.00e+00 718.00
IUUC-Csv-026298 Ciona savignyi 38.93 4.00e-57 215.00
IUUC-Dre-027492 Danio rerio 71.04 0.00e+00 1064.00
IUUC-Dno-030020 Dasypus novemcinctus 84.74 0.00e+00 1991.00
IUUC-Dor-031103 Dipodomys ordii 79.09 0.00e+00 2023.00
IUUC-Ete-032488 Echinops telfairi 78.77 0.00e+00 2023.00
IUUC-Eca-034066 Equus caballus 87.16 0.00e+00 2353.00
IUUC-Eeu-035199 Erinaceus europaeus 70.40 0.00e+00 741.00
IUUC-Fca-035434 Felis catus 85.01 0.00e+00 1958.00
IUUC-Fal-037113 Ficedula albicollis 75.59 0.00e+00 2043.00
IUUC-Gmo-039686 Gadus morhua 69.07 0.00e+00 1011.00
IUUC-Gga-040273 Gallus gallus 75.28 0.00e+00 2009.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.30 0.00e+00 1222.00
IUUC-Ggo-044643 Gorilla gorilla 86.30 0.00e+00 2280.00
IUUC-Hsa-046380 Homo sapiens 86.23 0.00e+00 2248.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 88.64 0.00e+00 1395.00
IUUC-Lch-050217 Latimeria chalumnae 65.29 0.00e+00 1704.00
IUUC-Lpe-051661 Leersia perrieri 29.70 2.00e-12 68.60
IUUC-Loc-052766 Lepisosteus oculatus 59.02 0.00e+00 1276.00
IUUC-Laf-053780 Loxodonta africana 84.96 0.00e+00 2300.00
IUUC-Mcc-054928 Macaca mulatta 86.33 0.00e+00 2284.00
IUUC-Meu-056184 Macropus eugenii 73.01 0.00e+00 769.00
IUUC-Mga-059576 Meleagris gallopavo 76.01 0.00e+00 2006.00
IUUC-Mmr-061045 Microcebus murinus 85.31 0.00e+00 2294.00
IUUC-Mdo-062576 Monodelphis domestica 79.96 0.00e+00 2127.00
IUUC-Mmu-063640 Mus musculus 84.52 0.00e+00 2219.00
IUUC-Mac-065303 Musa acuminata 29.22 4.00e-11 63.20
IUUC-Mpu-066512 Mustela putorius furo 86.87 0.00e+00 2315.00
IUUC-Mlu-067280 Myotis lucifugus 79.54 0.00e+00 1077.00
IUUC-Nle-069896 Nomascus leucogenys 86.52 0.00e+00 2173.00
IUUC-Ont-072197 Oreochromis niloticus 72.70 0.00e+00 1025.00
IUUC-Oan-072724 Ornithorhynchus anatinus 77.58 0.00e+00 1342.00
IUUC-Ocu-074758 Oryctolagus cuniculus 81.86 0.00e+00 2161.00
IUUC-Ogl-077641 Oryza glaberrima 27.12 3.00e-10 59.30
IUUC-Oin-079557 Oryza indica 27.75 5.00e-10 58.50
IUUC-Olo-080702 Oryza longistaminata 42.66 2.00e-44 174.00
IUUC-Opu-083371 Oryza punctata 41.88 2.00e-46 181.00
IUUC-Osa-085353 Oryza sativa 27.12 3.00e-10 59.30
IUUC-Oga-088702 Otolemur garnettii 85.58 0.00e+00 1976.00
IUUC-Oar-089736 Ovis aries 87.69 0.00e+00 2092.00
IUUC-Ptr-091055 Pan troglodytes 86.23 0.00e+00 2245.00
IUUC-Pan-092752 Papio anubis 91.72 0.00e+00 1379.00
IUUC-Psi-093620 Pelodiscus sinensis 78.03 0.00e+00 2060.00
IUUC-Pfo-097464 Poecilia formosa 51.24 0.00e+00 1205.00
IUUC-Pab-098051 Pongo abelii 86.78 0.00e+00 2270.00
IUUC-Pop-099927 Populus trichocarpa 30.96 9.00e-13 69.30
IUUC-Pca-100273 Procavia capensis 84.68 0.00e+00 2251.00
IUUC-Ppe-101635 Prunus persica 28.87 2.00e-11 64.30
IUUC-Pva-102473 Pteropus vampyrus 78.15 0.00e+00 1908.00
IUUC-Rno-105056 Rattus norvegicus 84.68 0.00e+00 2250.00
IUUC-Sha-107494 Sarcophilus harrisii 80.45 0.00e+00 2120.00
IUUC-Sar-113310 Sorex araneus 87.17 0.00e+00 1814.00
IUUC-Ssc-116344 Sus scrofa 87.01 0.00e+00 2304.00
IUUC-Tgu-116786 Taeniopygia guttata 77.05 0.00e+00 2042.00
IUUC-Tru-117638 Takifugu rubripes 50.22 0.00e+00 1230.00
IUUC-Tsy-118937 Tarsius syrichta 89.13 0.00e+00 1466.00
IUUC-Tni-120452 Tetraodon nigroviridis 52.91 0.00e+00 1160.00
IUUC-Tae-125237 Triticum aestivum 29.45 2.00e-07 49.30
IUUC-Tbe-127291 Tupaia belangeri 82.61 0.00e+00 1459.00
IUUC-Ttr-129017 Tursiops truncatus 85.46 0.00e+00 1792.00
IUUC-Xtr-132673 Xenopus tropicalis 66.11 0.00e+00 1744.00
IUUC-Xma-133695 Xiphophorus maculatus 73.00 0.00e+00 1005.00
Created Date 25-Jun-2017

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