iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074521

Ensembl Protein ID

ENSOCUP00000002485.2

UniProt Accession

G1SIH5; G1SIH5_RABIT

Genbank Protein ID

ENSOCUP00000002485

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02004348

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002863.2	ENSOCUT00000002862.2	ENSOCUP00000002485.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.70e-44	149.6	111	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           t++e  +ll++lq+++++ L+v+dvldk+++e ll+ e+++++ aae++gn++++++LLk++vqke+Wf++fl
   Q: 111  THDECFQLLNLLQPTLVDSLLVRDVLDKCVEEDLLTTEDRNRISAAENNGNESGVRELLKRIVQKENWFSTFL 183
           689********************************************************************96 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

KMSNGYSADK KFLYLLSCFR ARVKMYIQVE PVLDHLTFLP ADVREQIHRT ADTSGNVQAV 60
ELLLSTLEKQ IWPQGWAREF VEALKSAGSR LAARYLNPEL ADLPSPSFEN THDECFQLLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGTCGA ATGGTTATTC CGCAGACAAG AAGTTCCTCT ATCTCCTCTC ATGCTTCCGG 60
GCCAGAGTGA AAATGTACAT CCAGGTGGAG CCTGTCCTGG ACCACCTGAC CTTTCTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	82.02	0.00e+00	1604.00
IUUC-Apl-003900	Anas platyrhynchos	60.55	0.00e+00	1182.00
IUUC-Aca-005329	Anolis carolinensis	58.41	0.00e+00	1009.00
IUUC-Ame-011305	Astyanax mexicanus	47.31	0.00e+00	871.00
IUUC-Bta-012361	Bos taurus	81.02	0.00e+00	1532.00
IUUC-Cja-018760	Callithrix jacchus	84.34	0.00e+00	1596.00
IUUC-Cfa-020321	Canis familiaris	81.92	0.00e+00	1546.00
IUUC-Cpo-022450	Cavia porcellus	78.83	0.00e+00	1557.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	32.48	2.00e-12	68.20
IUUC-Csa-024194	Chlorocebus sabaeus	87.02	0.00e+00	1609.00
IUUC-Cho-024364	Choloepus hoffmanni	75.25	0.00e+00	1038.00
IUUC-Dre-028305	Danio rerio	54.38	0.00e+00	708.00
IUUC-Dno-029831	Dasypus novemcinctus	83.59	0.00e+00	1624.00
IUUC-Dor-030410	Dipodomys ordii	76.93	0.00e+00	1228.00
IUUC-Ete-032950	Echinops telfairi	74.60	0.00e+00	644.00
IUUC-Eca-034279	Equus caballus	84.75	0.00e+00	1601.00
IUUC-Eeu-034678	Erinaceus europaeus	77.73	0.00e+00	1510.00
IUUC-Fca-035618	Felis catus	84.89	0.00e+00	957.00
IUUC-Fal-037106	Ficedula albicollis	67.87	0.00e+00	972.00
IUUC-Fso-038398	Fusarium solani	25.58	8.00e-29	123.00
IUUC-Gmo-038598	Gadus morhua	49.58	0.00e+00	679.00
IUUC-Gga-040467	Gallus gallus	60.33	0.00e+00	1158.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.85	0.00e+00	822.00
IUUC-Ggo-045461	Gorilla gorilla	85.85	0.00e+00	1589.00
IUUC-Hsa-045771	Homo sapiens	85.85	0.00e+00	1587.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	82.15	0.00e+00	1556.00
IUUC-Lch-049913	Latimeria chalumnae	65.40	0.00e+00	907.00
IUUC-Loc-052768	Lepisosteus oculatus	52.91	0.00e+00	995.00
IUUC-Laf-053933	Loxodonta africana	82.63	0.00e+00	1571.00
IUUC-Mcc-054695	Macaca mulatta	87.12	0.00e+00	1615.00
IUUC-Meu-056829	Macropus eugenii	72.23	0.00e+00	1110.00
IUUC-Mga-059205	Meleagris gallopavo	60.72	0.00e+00	1156.00
IUUC-Mvi-060497	Microbotryum violaceum	31.52	3.00e-16	81.30
IUUC-Mmr-060703	Microcebus murinus	84.43	0.00e+00	1578.00
IUUC-Mdo-063079	Monodelphis domestica	70.34	0.00e+00	1418.00
IUUC-Mmu-064066	Mus musculus	77.88	0.00e+00	1582.00
IUUC-Mpu-066261	Mustela putorius furo	81.40	0.00e+00	1560.00
IUUC-Mlu-068196	Myotis lucifugus	81.15	0.00e+00	1525.00
IUUC-Nle-069479	Nomascus leucogenys	82.63	0.00e+00	1538.00
IUUC-Opr-070717	Ochotona princeps	78.51	0.00e+00	1222.00
IUUC-Ont-071702	Oreochromis niloticus	47.25	0.00e+00	854.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.21	0.00e+00	1191.00
IUUC-Ola-086351	Oryzias latipes	45.82	0.00e+00	786.00
IUUC-Oga-088539	Otolemur garnettii	82.32	0.00e+00	1546.00
IUUC-Oar-090186	Ovis aries	81.33	0.00e+00	1525.00
IUUC-Ptr-090575	Pan troglodytes	82.44	0.00e+00	1531.00
IUUC-Pan-092371	Papio anubis	87.02	0.00e+00	1611.00
IUUC-Psi-093072	Pelodiscus sinensis	62.74	0.00e+00	1231.00
IUUC-Pma-094345	Petromyzon marinus	44.07	1.00e-93	337.00
IUUC-Pfo-096401	Poecilia formosa	52.15	0.00e+00	675.00
IUUC-Pab-097623	Pongo abelii	85.27	0.00e+00	1596.00
IUUC-Pca-100993	Procavia capensis	76.63	0.00e+00	1297.00
IUUC-Pva-102227	Pteropus vampyrus	78.54	0.00e+00	1468.00
IUUC-Pgr-103529	Puccinia graminis	27.90	9.00e-30	126.00
IUUC-Rno-105198	Rattus norvegicus	77.28	0.00e+00	1562.00
IUUC-Sha-107622	Sarcophilus harrisii	71.86	0.00e+00	1404.00
IUUC-Sar-113625	Sorex araneus	68.20	0.00e+00	732.00
IUUC-Tgu-117486	Taeniopygia guttata	57.84	0.00e+00	1109.00
IUUC-Tru-118445	Takifugu rubripes	45.42	0.00e+00	808.00
IUUC-Tsy-119512	Tarsius syrichta	82.73	0.00e+00	1516.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.73	0.00e+00	828.00
IUUC-Tbe-127644	Tupaia belangeri	72.75	0.00e+00	1379.00
IUUC-Ttr-128989	Tursiops truncatus	77.81	0.00e+00	1537.00
IUUC-Vpa-130587	Vicugna pacos	77.12	0.00e+00	1221.00
IUUC-Xtr-132127	Xenopus tropicalis	53.07	0.00e+00	1014.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence