iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053936

UUCD1 version

UUC-LoA-00563

Ensembl Protein ID

ENSLAFP00000013583.4

UniProt Accession

G3TGH7; G3TGH7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016179.4	ENSLAFT00000034296.1	ENSLAFP00000026933.1
ENSLAFG00000016179.4	ENSLAFT00000031035.1	ENSLAFP00000020789.1
ENSLAFG00000016179.4	ENSLAFT00000016183.4	ENSLAFP00000013583.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-30	103.9	423	462
UBD/Beta-Prp	4.90e-62	210.2	333	622

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 423  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 462
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v+  k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 333  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCefKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTL 421
           7899************************************9999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++   
   Q: 422  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSETIVREME--L 504
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++v+ l+++++++el+s+s+d  +k+ dl+++ + +++ +      +  ++  fsp++ ++  gs++gs+++W + +g++ k+l++++
   Q: 505  LGKVTALDLNPDRTELLSCSRDDLLKIIDLRKNAVRQSFSAPGfkcsSDWTRAVFSPDGSFVTAGSAEGSLYVWSVLTGKVEKVLSKQH 593
           9******************************9999888777666666555668899********************************* PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss+i   ++s++++++v++++ sk+ +w+
   Q: 594  SSSINAVAWSPSGSHVVSVDKGSKAVLWS 622
           **************************996 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSSGLRAADF PRWKRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAHKLQAEK 60
HDVANRHEIS PGHDGTWNDG QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTCGG GCCTCCGCGC CGCCGATTTC CCCCGTTGGA AGCGCCACAT CTCCGAGGAG 60
CTGCGGCGCC GGGACCGGCT GCAGAGGCAG GCGTTTGAGG AGATCATCCT GCAGTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.67	4.00e-32	132.00
IUUC-Aml-002242	Ailuropoda melanoleuca	82.83	0.00e+00	1013.00
IUUC-Atr-003073	Amborella trichopoda	27.85	3.00e-27	116.00
IUUC-Apl-003384	Anas platyrhynchos	83.50	0.00e+00	1028.00
IUUC-Aca-004962	Anolis carolinensis	84.94	0.00e+00	1043.00
IUUC-Aly-005435	Arabidopsis lyrata	33.33	3.00e-44	172.00
IUUC-Ath-006948	Arabidopsis thaliana	33.67	5.00e-45	175.00
IUUC-Ame-010915	Astyanax mexicanus	79.14	3.00e-153	534.00
IUUC-Bta-012388	Bos taurus	92.47	0.00e+00	1155.00
IUUC-Bdi-014231	Brachypodium distachyon	29.15	5.00e-35	142.00
IUUC-Bol-016174	Brassica oleracea	33.33	2.00e-44	173.00
IUUC-Bra-017165	Brassica rapa	33.33	5.00e-44	172.00
IUUC-Cel-018234	Caenorhabditis elegans	36.30	1.00e-52	200.00
IUUC-Cja-018898	Callithrix jacchus	82.06	0.00e+00	958.00
IUUC-Cfa-020484	Canis familiaris	91.99	0.00e+00	1134.00
IUUC-Cpo-022156	Cavia porcellus	89.69	0.00e+00	1085.00
IUUC-Csa-024019	Chlorocebus sabaeus	88.30	0.00e+00	1074.00
IUUC-Cho-024311	Choloepus hoffmanni	78.21	0.00e+00	944.00
IUUC-Cin-025260	Ciona intestinalis	37.41	4.00e-100	358.00
IUUC-Csv-025836	Ciona savignyi	45.41	3.00e-48	184.00
IUUC-Dre-027702	Danio rerio	74.55	0.00e+00	892.00
IUUC-Dno-029728	Dasypus novemcinctus	91.99	0.00e+00	1167.00
IUUC-Dor-030587	Dipodomys ordii	82.78	2.00e-123	436.00
IUUC-Dme-031595	Drosophila melanogaster	38.43	6.00e-110	391.00
IUUC-Ete-032969	Echinops telfairi	75.53	0.00e+00	779.00
IUUC-Eca-034214	Equus caballus	90.96	0.00e+00	924.00
IUUC-Eeu-034537	Erinaceus europaeus	84.26	0.00e+00	873.00
IUUC-Fca-036005	Felis catus	92.57	0.00e+00	1083.00
IUUC-Fal-037593	Ficedula albicollis	85.61	0.00e+00	1007.00
IUUC-Gmo-039042	Gadus morhua	62.97	0.00e+00	671.00
IUUC-Gga-040986	Gallus gallus	85.26	0.00e+00	1071.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.10	0.00e+00	894.00
IUUC-Gma-043452	Glycine max	33.33	1.00e-45	177.00
IUUC-Ggo-045427	Gorilla gorilla	93.43	0.00e+00	1134.00
IUUC-Hsa-046632	Homo sapiens	90.54	0.00e+00	1115.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	87.34	0.00e+00	1060.00
IUUC-Lch-049439	Latimeria chalumnae	49.92	3.00e-144	504.00
IUUC-Lpe-051254	Leersia perrieri	29.72	2.00e-36	147.00
IUUC-Loc-052610	Lepisosteus oculatus	76.37	0.00e+00	931.00
IUUC-Mcc-055504	Macaca mulatta	90.60	0.00e+00	1147.00
IUUC-Meu-056516	Macropus eugenii	83.65	0.00e+00	1001.00
IUUC-Mtr-058062	Medicago truncatula	31.67	8.00e-42	164.00
IUUC-Mga-059777	Meleagris gallopavo	81.20	0.00e+00	1019.00
IUUC-Mmr-061298	Microcebus murinus	93.11	0.00e+00	1137.00
IUUC-Mdo-062969	Monodelphis domestica	88.30	0.00e+00	1083.00
IUUC-Mmu-064076	Mus musculus	91.48	0.00e+00	1098.00
IUUC-Mac-065022	Musa acuminata	32.11	9.00e-41	160.00
IUUC-Mpu-066196	Mustela putorius furo	93.59	0.00e+00	1142.00
IUUC-Mlu-067651	Myotis lucifugus	90.56	0.00e+00	1109.00
IUUC-Nle-069853	Nomascus leucogenys	89.26	0.00e+00	1095.00
IUUC-Opr-070350	Ochotona princeps	92.31	9.00e-117	414.00
IUUC-Ont-072489	Oreochromis niloticus	73.04	0.00e+00	889.00
IUUC-Oan-072703	Ornithorhynchus anatinus	83.33	0.00e+00	979.00
IUUC-Ocu-074205	Oryctolagus cuniculus	92.12	0.00e+00	1133.00
IUUC-Oba-075619	Oryza barthii	30.14	3.00e-35	142.00
IUUC-Obr-076632	Oryza brachyantha	29.51	5.00e-36	145.00
IUUC-Ogl-077671	Oryza glaberrima	30.14	3.00e-35	143.00
IUUC-Ogu-078052	Oryza glumaepatula	30.14	3.00e-35	142.00
IUUC-Oin-079611	Oryza indica	29.79	3.00e-33	135.00
IUUC-Olo-080408	Oryza longistaminata	30.14	4.00e-35	142.00
IUUC-Ome-081560	Oryza meridionalis	30.14	2.00e-35	143.00
IUUC-Oni-082145	Oryza nivara	30.14	3.00e-35	142.00
IUUC-Opu-083918	Oryza punctata	29.79	1.00e-34	141.00
IUUC-Oru-084858	Oryza rufipogon	29.79	6.00e-33	135.00
IUUC-Osa-086277	Oryza sativa	29.79	4.00e-33	135.00
IUUC-Ola-086816	Oryzias latipes	69.85	1.00e-99	355.00
IUUC-Olu-087622	Ostreococcus lucimarinus	31.77	2.00e-41	162.00
IUUC-Oga-088765	Otolemur garnettii	86.56	0.00e+00	1023.00
IUUC-Oar-090196	Ovis aries	88.87	0.00e+00	1002.00
IUUC-Ptr-091676	Pan troglodytes	90.71	0.00e+00	1117.00
IUUC-Pan-092068	Papio anubis	94.23	0.00e+00	1138.00
IUUC-Psi-093367	Pelodiscus sinensis	83.33	0.00e+00	1014.00
IUUC-Ppa-095699	Physcomitrella patens	33.44	9.00e-41	160.00
IUUC-Pfo-096067	Poecilia formosa	70.92	0.00e+00	860.00
IUUC-Pab-098111	Pongo abelii	93.27	0.00e+00	1131.00
IUUC-Pop-099116	Populus trichocarpa	31.00	1.00e-41	164.00
IUUC-Pca-100680	Procavia capensis	88.53	0.00e+00	986.00
IUUC-Pva-102871	Pteropus vampyrus	92.32	0.00e+00	1061.00
IUUC-Rno-106088	Rattus norvegicus	91.80	0.00e+00	1103.00
IUUC-Sha-106984	Sarcophilus harrisii	85.86	0.00e+00	1046.00
IUUC-Smo-109404	Selaginella moellendorffii	29.39	1.00e-39	157.00
IUUC-Sit-110828	Setaria italica	31.19	5.00e-39	155.00
IUUC-Sly-111009	Solanum lycopersicum	31.33	2.00e-44	173.00
IUUC-Stu-112370	Solanum tuberosum	31.33	3.00e-45	176.00
IUUC-Sar-113659	Sorex araneus	58.47	2.00e-86	311.00
IUUC-Ssc-116241	Sus scrofa	88.58	0.00e+00	1080.00
IUUC-Tgu-116576	Taeniopygia guttata	83.65	0.00e+00	1058.00
IUUC-Tru-118336	Takifugu rubripes	64.38	0.00e+00	737.00
IUUC-Tsy-119006	Tarsius syrichta	89.26	0.00e+00	1074.00
IUUC-Tni-120300	Tetraodon nigroviridis	72.27	0.00e+00	859.00
IUUC-Tca-121002	Theobroma cacao	32.77	2.00e-44	173.00
IUUC-Tae-124868	Triticum aestivum	30.07	2.00e-33	137.00
IUUC-Tur-126463	Triticum urartu	28.67	1.00e-32	134.00
IUUC-Tbe-127631	Tupaia belangeri	90.28	0.00e+00	893.00
IUUC-Ttr-129005	Tursiops truncatus	82.04	2.00e-158	552.00
IUUC-Vpa-130246	Vicugna pacos	84.71	0.00e+00	847.00
IUUC-Vvi-130878	Vitis vinifera	32.69	8.00e-43	168.00
IUUC-Xtr-132798	Xenopus tropicalis	72.13	0.00e+00	860.00
IUUC-Xma-133264	Xiphophorus maculatus	70.59	0.00e+00	858.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence