iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060202

Ensembl Protein ID

ENSMGAP00000005601.2

UniProt Accession

G1N1Z9; G1N1Z9_MELGA

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005618.2	ENSMGAT00000006341.2	ENSMGAP00000005601.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-30	102.7	529	566
UBD/Beta-Prp	2.60e-52	177.6	430	608

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt++vt+l++  +  ++lvs+++Dgt +vWD+ +  +
   Q: 529  GHTAKVTSLSWspHHeGRLVSACYDGTAQVWDVMKEEP 566
           8***********733699**************977665 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.......ilvtgseDrtikvwdls........... 82
             t + ++pd++lla g +dg+i+++++ + kll ++++h + ++a++++++         ++++gs  ++i+v +l+           
   Q: 430  ARTEISWKPDGKLLALGNEDGSIEIFQAPSLKLLCTIQQHHKLINAIRWHHEHGsdpelsyLIASGSVNAIIYVHNLKsviestsespl 518
           5678999********************************************988899***9**************99999999999999 PP
   S: 83   .tgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlkt 168
              ++++tl gh+++v+sls+sp    +lvs+  d t++vwd+ +++ l    +gh+g   cv+++p + + + +G++D  v  W ++ 
   Q: 519  tITEPFRTLVGHTAKVTSLSWSPhHEGRLVSACYDGTAQVWDVMKEEPLC-NYRGHQGRLLCVQWSPVDsDSVYTGADDFSVHKWLISK 606
           889999*****************555***********************9.9*****************9***************9954 PP
   S: 169  gk 170
           ++
   Q: 607  QE 608
           43 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QNAITALHWS PLVKDLIVSG DEKGVIVCYW HSRSDSQQFF PEPRTIFCLT CSPHHENLVA 60
IGYKDGMVVI IDISRKKEVL HRLRGHDDEI HCLAWCPVPG EGRLPAWQDE LQEEGDVPNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAATGCAA TCACAGCGTT ACACTGGTCA CCCCTTGTGA AAGATCTGAT TGTATCTGGT 60
GATGAAAAAG GGGTAATTGT TTGTTACTGG CATAGCAGAA GTGACAGCCA GCAATTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	62.45	0.00e+00	1679.00
IUUC-Apl-003586	Anas platyrhynchos	87.04	0.00e+00	2357.00
IUUC-Aca-004956	Anolis carolinensis	65.02	0.00e+00	1814.00
IUUC-Ame-010753	Astyanax mexicanus	64.26	0.00e+00	877.00
IUUC-Bta-012315	Bos taurus	62.55	0.00e+00	1675.00
IUUC-Cja-019334	Callithrix jacchus	62.09	0.00e+00	1665.00
IUUC-Cfa-021254	Canis familiaris	61.98	0.00e+00	1706.00
IUUC-Cpo-021984	Cavia porcellus	59.85	0.00e+00	1585.00
IUUC-Csa-023650	Chlorocebus sabaeus	62.87	0.00e+00	1657.00
IUUC-Cho-024860	Choloepus hoffmanni	58.77	0.00e+00	1494.00
IUUC-Cin-025778	Ciona intestinalis	42.28	2.00e-138	486.00
IUUC-Csv-026313	Ciona savignyi	40.98	6.00e-142	497.00
IUUC-Dre-028096	Danio rerio	64.38	0.00e+00	862.00
IUUC-Dno-029799	Dasypus novemcinctus	66.87	0.00e+00	1507.00
IUUC-Dor-030885	Dipodomys ordii	58.26	2.00e-128	453.00
IUUC-Ete-032918	Echinops telfairi	59.62	0.00e+00	1583.00
IUUC-Eca-034144	Equus caballus	62.57	0.00e+00	1678.00
IUUC-Eeu-034843	Erinaceus europaeus	61.16	0.00e+00	1336.00
IUUC-Fca-035948	Felis catus	62.30	0.00e+00	1670.00
IUUC-Fal-037303	Ficedula albicollis	82.09	0.00e+00	2315.00
IUUC-Gmo-039591	Gadus morhua	53.27	0.00e+00	702.00
IUUC-Gga-040570	Gallus gallus	91.64	0.00e+00	2461.00
IUUC-Gac-042646	Gasterosteus aculeatus	47.62	0.00e+00	1207.00
IUUC-Ggo-045605	Gorilla gorilla	60.78	0.00e+00	1231.00
IUUC-Hsa-046122	Homo sapiens	63.51	0.00e+00	1665.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	66.92	0.00e+00	1526.00
IUUC-Lch-050489	Latimeria chalumnae	46.17	0.00e+00	782.00
IUUC-Loc-052259	Lepisosteus oculatus	62.48	0.00e+00	823.00
IUUC-Laf-053338	Loxodonta africana	63.32	0.00e+00	1668.00
IUUC-Mcc-055442	Macaca mulatta	62.90	0.00e+00	1658.00
IUUC-Meu-056245	Macropus eugenii	58.37	0.00e+00	666.00
IUUC-Mmr-061730	Microcebus murinus	61.69	0.00e+00	1640.00
IUUC-Mdo-062880	Monodelphis domestica	64.73	0.00e+00	1771.00
IUUC-Mmu-063930	Mus musculus	61.79	0.00e+00	1608.00
IUUC-Mpu-066605	Mustela putorius furo	61.74	0.00e+00	1662.00
IUUC-Mlu-067765	Myotis lucifugus	62.51	0.00e+00	1709.00
IUUC-Nle-069183	Nomascus leucogenys	62.13	0.00e+00	1618.00
IUUC-Opr-070659	Ochotona princeps	52.50	0.00e+00	743.00
IUUC-Ont-072356	Oreochromis niloticus	62.84	0.00e+00	855.00
IUUC-Oan-073056	Ornithorhynchus anatinus	65.21	0.00e+00	1750.00
IUUC-Ocu-073881	Oryctolagus cuniculus	62.25	0.00e+00	1726.00
IUUC-Ola-087120	Oryzias latipes	67.31	2.00e-41	161.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.19	2.00e-28	121.00
IUUC-Oga-088343	Otolemur garnettii	63.20	0.00e+00	1681.00
IUUC-Oar-089257	Ovis aries	63.30	0.00e+00	1710.00
IUUC-Ptr-090497	Pan troglodytes	63.22	0.00e+00	1656.00
IUUC-Pan-092638	Papio anubis	62.68	0.00e+00	1649.00
IUUC-Psi-093096	Pelodiscus sinensis	71.49	0.00e+00	1833.00
IUUC-Pma-094571	Petromyzon marinus	52.85	9.00e-65	240.00
IUUC-Pfo-096742	Poecilia formosa	48.11	0.00e+00	1236.00
IUUC-Pab-098153	Pongo abelii	62.26	0.00e+00	1665.00
IUUC-Pca-100957	Procavia capensis	60.04	0.00e+00	1552.00
IUUC-Pva-102439	Pteropus vampyrus	62.54	0.00e+00	1712.00
IUUC-Rno-105891	Rattus norvegicus	62.02	0.00e+00	1578.00
IUUC-Sha-107181	Sarcophilus harrisii	65.62	0.00e+00	1756.00
IUUC-Ssc-115413	Sus scrofa	62.08	0.00e+00	1697.00
IUUC-Tgu-117082	Taeniopygia guttata	83.49	0.00e+00	2251.00
IUUC-Tru-118491	Takifugu rubripes	60.19	0.00e+00	791.00
IUUC-Tsy-119629	Tarsius syrichta	68.28	4.00e-115	409.00
IUUC-Tni-120240	Tetraodon nigroviridis	61.48	0.00e+00	822.00
IUUC-Tbe-127673	Tupaia belangeri	55.31	0.00e+00	1355.00
IUUC-Ttr-128562	Tursiops truncatus	59.59	0.00e+00	1582.00
IUUC-Vpa-130596	Vicugna pacos	65.02	0.00e+00	1254.00
IUUC-Xtr-132469	Xenopus tropicalis	55.97	0.00e+00	1492.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence