iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062493

Ensembl Protein ID

ENSMODP00000011695.3

UniProt Accession

F7G015; F7G015_MONDO

Protein Name

Uncharacterized protein

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000009352.4	ENSMODT00000011916.3	ENSMODP00000011695.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-22	77.9	614	652

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 614  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 652
           8***********999*********************998 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCCGC AAAGCCGGCA CCCGGTAAGG AACGGCTGGG CCCTGGGCCC CTGGGCGTAT 60
GCTTGAGGGT GCGACGGGGT GGGGGAGTAT GGGGGGGGGA GGTTAGGTGA ATGTTTTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

KEGG

mdo:100021846

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	94.45	0.00e+00	1259.00
IUUC-Apl-003594	Anas platyrhynchos	95.62	0.00e+00	1256.00
IUUC-Aca-005053	Anolis carolinensis	95.00	0.00e+00	1297.00
IUUC-Bta-013380	Bos taurus	90.40	0.00e+00	1157.00
IUUC-Cja-019135	Callithrix jacchus	98.83	0.00e+00	1310.00
IUUC-Cfa-020611	Canis familiaris	98.74	0.00e+00	1192.00
IUUC-Cpo-022495	Cavia porcellus	98.05	0.00e+00	1303.00
IUUC-Csa-024056	Chlorocebus sabaeus	98.70	0.00e+00	1327.00
IUUC-Csv-026174	Ciona savignyi	57.45	4.00e-162	565.00
IUUC-Dno-029011	Dasypus novemcinctus	98.44	0.00e+00	1308.00
IUUC-Ete-032533	Echinops telfairi	86.36	0.00e+00	1191.00
IUUC-Eca-033351	Equus caballus	99.09	0.00e+00	1313.00
IUUC-Eeu-034666	Erinaceus europaeus	99.31	0.00e+00	1079.00
IUUC-Fca-036429	Felis catus	91.75	0.00e+00	1275.00
IUUC-Fal-036696	Ficedula albicollis	98.74	0.00e+00	1268.00
IUUC-Gmo-038805	Gadus morhua	80.99	0.00e+00	1175.00
IUUC-Gga-041113	Gallus gallus	98.70	0.00e+00	1367.00
IUUC-Gac-041999	Gasterosteus aculeatus	80.74	0.00e+00	1181.00
IUUC-Ggo-045164	Gorilla gorilla	98.83	0.00e+00	1328.00
IUUC-Hsa-047011	Homo sapiens	98.83	0.00e+00	1328.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	93.54	0.00e+00	1263.00
IUUC-Lch-050437	Latimeria chalumnae	95.57	0.00e+00	1132.00
IUUC-Loc-052819	Lepisosteus oculatus	91.17	0.00e+00	1241.00
IUUC-Laf-053862	Loxodonta africana	95.77	0.00e+00	1276.00
IUUC-Mcc-055735	Macaca mulatta	94.65	0.00e+00	1310.00
IUUC-Mmr-061207	Microcebus murinus	95.26	0.00e+00	1262.00
IUUC-Mmu-063795	Mus musculus	93.22	0.00e+00	1268.00
IUUC-Mpu-065819	Mustela putorius furo	98.57	0.00e+00	1336.00
IUUC-Mlu-067047	Myotis lucifugus	98.96	0.00e+00	1297.00
IUUC-Nle-069684	Nomascus leucogenys	98.57	0.00e+00	1320.00
IUUC-Opr-071172	Ochotona princeps	97.66	0.00e+00	1287.00
IUUC-Ont-072102	Oreochromis niloticus	81.20	0.00e+00	1191.00
IUUC-Ocu-074592	Oryctolagus cuniculus	95.06	0.00e+00	1314.00
IUUC-Ola-087267	Oryzias latipes	79.34	0.00e+00	1109.00
IUUC-Oga-088629	Otolemur garnettii	95.77	0.00e+00	1267.00
IUUC-Oar-089551	Ovis aries	97.67	0.00e+00	1288.00
IUUC-Ptr-091207	Pan troglodytes	98.44	0.00e+00	1322.00
IUUC-Pan-091822	Papio anubis	94.65	0.00e+00	1310.00
IUUC-Psi-093594	Pelodiscus sinensis	95.87	0.00e+00	1290.00
IUUC-Pfo-096239	Poecilia formosa	80.89	0.00e+00	1184.00
IUUC-Pab-097687	Pongo abelii	98.82	0.00e+00	1312.00
IUUC-Pva-102355	Pteropus vampyrus	95.24	0.00e+00	1203.00
IUUC-Rno-106027	Rattus norvegicus	96.37	0.00e+00	1318.00
IUUC-Sha-107419	Sarcophilus harrisii	95.01	0.00e+00	1295.00
IUUC-Sar-113585	Sorex araneus	86.51	0.00e+00	714.00
IUUC-Ssc-116151	Sus scrofa	98.83	0.00e+00	1310.00
IUUC-Tgu-117387	Taeniopygia guttata	98.05	0.00e+00	1340.00
IUUC-Tru-118051	Takifugu rubripes	76.88	0.00e+00	1131.00
IUUC-Tsy-119342	Tarsius syrichta	91.47	0.00e+00	1021.00
IUUC-Tbe-127881	Tupaia belangeri	95.97	0.00e+00	1296.00
IUUC-Ttr-129082	Tursiops truncatus	89.22	0.00e+00	1153.00
IUUC-Xtr-131792	Xenopus tropicalis	90.08	0.00e+00	1246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence