iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062312

UUCD1 version

UUC-MoD-00475

Ensembl Protein ID

ENSMODP00000019895.1

UniProt Accession

F6Z333; F6Z333_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015943.3	ENSMODT00000020251.1	ENSMODP00000019895.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-31	107.7	395	426
UBD/Beta-Prp	8.20e-49	166.5	393	671

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s  +ll sGs D+tikvWD+
   Q: 395  GHQGPVWCLCVySMgDLLFSGSSDKTIKVWDT 426
           8*********778889***************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+  v+ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++     l +gs D ti vwd+++ + v t+++
   Q: 393  FVGHQGPVW-CLCVYSMGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGC--KLYSGSADCTIIVWDIQNLQKVNTIRA 478
           556666555.59999*******************846678899***************99..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n+l sGs+ +t+++Wd+++ ++++ l+    
   Q: 479  HDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVASQ--NYLYSGSY-QTIKIWDIRNLECIHVLQT-SG 560
           *******99999..9******.9*******7368888888**************99..*******9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 561  GSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 647
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 648  TALAV---SRGRLFSGAVDSTVKVWTC 671
           ****9...*****************86 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSSSKSARYN RFSGGPANLP PSDSTNGTRM ETTFGPAFSA VTTITKVADG TSTYKQHRRT 60
PSSSSTLTYS QRDEEDSMPP INTPRRSDSA ISVRSLHSES SMSLRSTFSL HEEEEEPEPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTCAA GCAAGAGTGC ACGATATAAT CGTTTCTCTG GTGGCCCAGC AAACCTCCCT 60
CCCTCGGACA GCACAAACGG GGTAAGGGTG AGAGCAGGCA CTCCTCTGAG TTGCTCCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

mdo:100011568

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	95.10	0.00e+00	1237.00
IUUC-Apl-004098	Anas platyrhynchos	96.26	0.00e+00	1213.00
IUUC-Aca-004852	Anolis carolinensis	90.24	0.00e+00	994.00
IUUC-Ame-011275	Astyanax mexicanus	83.89	0.00e+00	944.00
IUUC-Bta-013153	Bos taurus	96.13	0.00e+00	1256.00
IUUC-Cja-019243	Callithrix jacchus	94.96	0.00e+00	1212.00
IUUC-Cfa-020036	Canis familiaris	96.13	0.00e+00	1266.00
IUUC-Cpo-022194	Cavia porcellus	95.66	0.00e+00	1253.00
IUUC-Csa-023363	Chlorocebus sabaeus	95.98	0.00e+00	1261.00
IUUC-Cin-025279	Ciona intestinalis	58.89	0.00e+00	797.00
IUUC-Csv-026163	Ciona savignyi	64.18	0.00e+00	769.00
IUUC-Dre-027998	Danio rerio	91.59	0.00e+00	1122.00
IUUC-Dno-029356	Dasypus novemcinctus	93.75	7.00e-129	452.00
IUUC-Dor-030750	Dipodomys ordii	93.44	0.00e+00	1213.00
IUUC-Eca-033671	Equus caballus	80.59	0.00e+00	971.00
IUUC-Eeu-034765	Erinaceus europaeus	96.38	1.00e-164	573.00
IUUC-Fca-035843	Felis catus	96.42	0.00e+00	1270.00
IUUC-Fal-037237	Ficedula albicollis	94.93	0.00e+00	1255.00
IUUC-Gmo-038779	Gadus morhua	82.01	0.00e+00	1015.00
IUUC-Gga-040579	Gallus gallus	94.49	0.00e+00	1247.00
IUUC-Gac-042233	Gasterosteus aculeatus	86.76	0.00e+00	1128.00
IUUC-Gma-042914	Glycine max	27.54	7.00e-19	88.20
IUUC-Ggo-045147	Gorilla gorilla	95.83	0.00e+00	1261.00
IUUC-Hsa-046117	Homo sapiens	95.98	0.00e+00	1263.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	96.27	0.00e+00	1271.00
IUUC-Lch-050593	Latimeria chalumnae	91.96	0.00e+00	1196.00
IUUC-Loc-052444	Lepisosteus oculatus	91.57	0.00e+00	1225.00
IUUC-Laf-053499	Loxodonta africana	89.91	0.00e+00	1162.00
IUUC-Mcc-055038	Macaca mulatta	96.13	0.00e+00	1264.00
IUUC-Meu-056610	Macropus eugenii	97.61	0.00e+00	967.00
IUUC-Mtr-057641	Medicago truncatula	27.73	6.00e-20	92.00
IUUC-Mga-060183	Meleagris gallopavo	94.35	0.00e+00	1244.00
IUUC-Mmr-061133	Microcebus murinus	94.45	0.00e+00	1189.00
IUUC-Mmu-063844	Mus musculus	95.83	0.00e+00	1231.00
IUUC-Mpu-066552	Mustela putorius furo	95.83	0.00e+00	1234.00
IUUC-Mlu-067719	Myotis lucifugus	95.83	0.00e+00	1229.00
IUUC-Nle-070045	Nomascus leucogenys	97.12	0.00e+00	1188.00
IUUC-Opr-070927	Ochotona princeps	93.00	0.00e+00	1201.00
IUUC-Ont-072680	Oreochromis niloticus	87.05	0.00e+00	1155.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.00	2.00e-52	196.00
IUUC-Ogu-077987	Oryza glumaepatula	25.43	1.00e-18	87.80
IUUC-Ola-087454	Oryzias latipes	90.09	0.00e+00	1189.00
IUUC-Oga-088380	Otolemur garnettii	96.13	0.00e+00	1263.00
IUUC-Oar-089558	Ovis aries	78.20	0.00e+00	987.00
IUUC-Ptr-091606	Pan troglodytes	95.83	0.00e+00	1261.00
IUUC-Pan-092227	Papio anubis	96.13	0.00e+00	1264.00
IUUC-Psi-093853	Pelodiscus sinensis	87.60	0.00e+00	1032.00
IUUC-Pma-094541	Petromyzon marinus	80.70	3.00e-154	537.00
IUUC-Pfo-096237	Poecilia formosa	86.58	0.00e+00	1145.00
IUUC-Pab-097589	Pongo abelii	95.98	0.00e+00	1263.00
IUUC-Pca-100375	Procavia capensis	92.50	0.00e+00	1166.00
IUUC-Ppe-101355	Prunus persica	27.00	4.00e-17	82.80
IUUC-Pva-102434	Pteropus vampyrus	95.83	0.00e+00	1258.00
IUUC-Rno-105443	Rattus norvegicus	96.27	0.00e+00	1238.00
IUUC-Sha-106517	Sarcophilus harrisii	99.70	0.00e+00	1313.00
IUUC-Sly-111122	Solanum lycopersicum	27.27	1.00e-17	84.30
IUUC-Ssc-115990	Sus scrofa	95.23	0.00e+00	1253.00
IUUC-Tgu-117222	Taeniopygia guttata	94.46	0.00e+00	1242.00
IUUC-Tru-118392	Takifugu rubripes	89.51	0.00e+00	1149.00
IUUC-Tni-120220	Tetraodon nigroviridis	88.70	0.00e+00	1146.00
IUUC-Tca-121793	Theobroma cacao	26.37	1.00e-19	90.50
IUUC-Tbe-128045	Tupaia belangeri	97.92	4.00e-160	558.00
IUUC-Ttr-128203	Tursiops truncatus	92.70	0.00e+00	1202.00
IUUC-Xtr-132043	Xenopus tropicalis	92.55	0.00e+00	1252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence