iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093417

Ensembl Protein ID

ENSPSIP00000014425.1

UniProt Accession

K7G2B4; K7G2B4_PELSI

Genbank Protein ID

ENSPSIP00000014425

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01143195

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000012536.1	ENSPSIT00000014493.1	ENSPSIP00000014425.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-58	189.9	40	77
UBD/Beta-Prp	2.80e-124	414.1	661	876

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvl 35
           Ht ++ claf  d  +lvs + D  +ti vWD+r+g+ 
   Q: 40   HTHGIACLAFdLDgQRLVSVGLDskNTICVWDWRKGKM 77
           99*********66699*****9999*********9986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd+++ +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++++g
   Q: 661  HDDDILCLAIHPLKDYVATGqvGRDSSVHIWDTETIKPLSVLkGYHQYGVCAVDFSADGKRLASVGIDdnHTIVLWDWKKGEKLSAFRG 749
           4555566************96669******************5559******************9999999****************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
            +d++  ++++p+  dkl++++  +  + w    g  +         g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t +
   Q: 750  SKDKIFVVKINPYIpDKLITAG-IKHMKFWRRAGGGLIGRkgciGAMGRTDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDLFLIKTVK 835
           ************9978888887.9999***87777777668887899******************************..889******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
             h+++v s+   +  k +v+g++dg v lwd   ++c++t+  
   Q: 836  A-HDGPVFSMHALE--KGFVTGGKDGVVALWDDTFERCLKTYAI 876
           8.********9888..67**********************9965 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

SLALHPHAAL PCILQVGKEP YICVWDSYTV QTISILKDVH THGIACLAFD LDGQRLVSVG 60
LDSKNTICVW DWRKGKMLSM APGHTDRIFD ISWDLYQPNK LVSCGVKHIK FWSLCGNSLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTTGCCC TGCATCCTCA TAGCATGTGC TGTGAGTATC ATTGTGGCCC TTGGGGCTTC 60
CAAAGTTGAG TAGCTCTGGC CTAGATCATC CCTGACAGGA TTTTTGTTTA AGGAATTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR003143--Cyt_cd1_C
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	90.39	0.00e+00	3565.00
IUUC-Apl-003360	Anas platyrhynchos	95.62	0.00e+00	3678.00
IUUC-Ame-011681	Astyanax mexicanus	86.62	0.00e+00	3441.00
IUUC-Bta-012838	Bos taurus	89.93	0.00e+00	3545.00
IUUC-Cja-019068	Callithrix jacchus	90.34	0.00e+00	3538.00
IUUC-Cfa-020531	Canis familiaris	90.18	0.00e+00	3578.00
IUUC-Cpo-022304	Cavia porcellus	86.99	0.00e+00	3444.00
IUUC-Csa-023621	Chlorocebus sabaeus	90.05	0.00e+00	3358.00
IUUC-Cho-024944	Choloepus hoffmanni	71.77	0.00e+00	1418.00
IUUC-Dre-028772	Danio rerio	86.01	0.00e+00	3433.00
IUUC-Dno-030063	Dasypus novemcinctus	89.53	0.00e+00	3507.00
IUUC-Dor-030980	Dipodomys ordii	82.35	0.00e+00	1524.00
IUUC-Ete-032554	Echinops telfairi	90.34	0.00e+00	1027.00
IUUC-Eca-033909	Equus caballus	90.97	0.00e+00	3415.00
IUUC-Eeu-035180	Erinaceus europaeus	74.42	0.00e+00	1396.00
IUUC-Fal-037219	Ficedula albicollis	95.57	0.00e+00	3683.00
IUUC-Gmo-039146	Gadus morhua	81.84	0.00e+00	3243.00
IUUC-Gga-041095	Gallus gallus	95.15	0.00e+00	2607.00
IUUC-Gac-041341	Gasterosteus aculeatus	84.35	0.00e+00	3330.00
IUUC-Hsa-045997	Homo sapiens	90.76	0.00e+00	3551.00
IUUC-Lch-050306	Latimeria chalumnae	86.93	0.00e+00	3263.00
IUUC-Loc-052215	Lepisosteus oculatus	87.43	0.00e+00	3503.00
IUUC-Laf-054044	Loxodonta africana	89.42	0.00e+00	3518.00
IUUC-Mcc-054733	Macaca mulatta	90.55	0.00e+00	3540.00
IUUC-Meu-055977	Macropus eugenii	78.92	0.00e+00	922.00
IUUC-Mga-059666	Meleagris gallopavo	94.32	0.00e+00	3629.00
IUUC-Mmr-060995	Microcebus murinus	90.55	0.00e+00	3535.00
IUUC-Mdo-062482	Monodelphis domestica	91.59	0.00e+00	3598.00
IUUC-Mmu-063533	Mus musculus	89.50	0.00e+00	3492.00
IUUC-Mpu-066704	Mustela putorius furo	90.18	0.00e+00	3557.00
IUUC-Mlu-067592	Myotis lucifugus	89.71	0.00e+00	3525.00
IUUC-Nle-069911	Nomascus leucogenys	90.39	0.00e+00	3538.00
IUUC-Ont-071966	Oreochromis niloticus	86.14	0.00e+00	3444.00
IUUC-Ola-086738	Oryzias latipes	85.48	0.00e+00	3388.00
IUUC-Oga-088436	Otolemur garnettii	87.88	0.00e+00	3452.00
IUUC-Oar-090153	Ovis aries	90.09	0.00e+00	3545.00
IUUC-Ptr-091008	Pan troglodytes	90.45	0.00e+00	3528.00
IUUC-Pan-092404	Papio anubis	90.23	0.00e+00	3528.00
IUUC-Pfo-096073	Poecilia formosa	86.42	0.00e+00	3446.00
IUUC-Pab-097900	Pongo abelii	90.08	0.00e+00	3524.00
IUUC-Pca-100107	Procavia capensis	75.77	0.00e+00	2406.00
IUUC-Pva-102880	Pteropus vampyrus	86.63	0.00e+00	3341.00
IUUC-Rno-106084	Rattus norvegicus	89.61	0.00e+00	3549.00
IUUC-Sha-106974	Sarcophilus harrisii	91.60	0.00e+00	3592.00
IUUC-Sar-113401	Sorex araneus	79.25	0.00e+00	1733.00
IUUC-Ssc-116057	Sus scrofa	90.10	0.00e+00	3587.00
IUUC-Tru-118444	Takifugu rubripes	85.21	0.00e+00	3366.00
IUUC-Tsy-118941	Tarsius syrichta	79.34	0.00e+00	2693.00
IUUC-Tni-120683	Tetraodon nigroviridis	84.76	0.00e+00	3338.00
IUUC-Tbe-127467	Tupaia belangeri	82.27	0.00e+00	1748.00
IUUC-Ttr-129138	Tursiops truncatus	86.42	0.00e+00	3365.00
IUUC-Vpa-130083	Vicugna pacos	84.59	0.00e+00	3268.00
IUUC-Xtr-131835	Xenopus tropicalis	89.99	0.00e+00	3565.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence