iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033382

UUCD1 version

UUC-EqC-00425

Ensembl Protein ID

ENSECAP00000021646.1

UniProt Accession

F6WZY3; F6WZY3_HORSE

Protein Name

Uncharacterized protein

Gene Name

LONRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024139.1	ENSECAT00000025985.1	ENSECAP00000021646.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-08	34.1	465	503
E3 activity/RING/U-box	2.30e-11	43.8	462	529

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f + p+++pCgH+f+++Cl++          +++CPlC+
   Q: 465  CSLCMRLFYE-PVTTPCGHTFCLKCLERC------LDHNAKCPLCK 503
           ****999977.***************999......9*********7 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpl....teedlvPnltlrrliqawc 69
           ++ C++ + l+ +Pv++p+G+t+  +++e++l+++ k cP+++  l    ++++   n  + +li +++
   Q: 462  DLECSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNAK-CPLCKDGLsqclASRKYSKNVIMEELIAKFL 529
           678*********************************9.****876633336777788888888887776 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDSFQAGQML SLPAELGSNL ELAEPAASAA RVDTGPHPEA ATEGPALLPT QEPEQGQPPR 60
ASTPECKVLL TQADALASGG RLREALEVYR QLSERQQLVA EQLEQLVRCL AENVPQGEAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCCTTTTC TCCGCGCGTG TCCCTCTCCC TATGGATTCA TTTCAGGCTG GACAGATGCT 60
GAGCTTGCCC GCCGAGCTCG GCAGCAACTT AGAGCTGGCG GAGCCGGCGG CATCAGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50005--TPR
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

ecb:100053629

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000755	Aegilops tauschii	28.42	9.00e-11	61.20
IUUC-Aml-001774	Ailuropoda melanoleuca	78.62	0.00e+00	1020.00
IUUC-Apl-003916	Anas platyrhynchos	62.43	0.00e+00	644.00
IUUC-Aca-004822	Anolis carolinensis	48.09	5.00e-169	587.00
IUUC-Ani-009473	Aspergillus nidulans	31.56	2.00e-42	166.00
IUUC-Ame-010750	Astyanax mexicanus	44.12	1.00e-164	573.00
IUUC-Bta-012872	Bos taurus	91.83	0.00e+00	1198.00
IUUC-Cel-018356	Caenorhabditis elegans	30.12	6.00e-10	56.60
IUUC-Cja-018747	Callithrix jacchus	81.50	0.00e+00	1052.00
IUUC-Cfa-020101	Canis familiaris	87.34	0.00e+00	1146.00
IUUC-Cpo-022041	Cavia porcellus	78.80	0.00e+00	1021.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	32.00	2.00e-09	55.80
IUUC-Csa-024034	Chlorocebus sabaeus	88.41	0.00e+00	1207.00
IUUC-Cin-025668	Ciona intestinalis	34.10	3.00e-99	355.00
IUUC-Csv-026364	Ciona savignyi	45.87	2.00e-79	289.00
IUUC-Dre-028400	Danio rerio	50.72	3.00e-142	498.00
IUUC-Dno-029518	Dasypus novemcinctus	80.80	0.00e+00	1049.00
IUUC-Dor-031132	Dipodomys ordii	71.13	0.00e+00	983.00
IUUC-Dse-031331	Dothistroma septosporum	31.62	4.00e-39	155.00
IUUC-Fca-035777	Felis catus	79.13	0.00e+00	744.00
IUUC-Fal-036730	Ficedula albicollis	62.64	0.00e+00	664.00
IUUC-Gmo-039110	Gadus morhua	48.99	4.00e-176	611.00
IUUC-Gga-041187	Gallus gallus	58.19	0.00e+00	833.00
IUUC-Gac-042201	Gasterosteus aculeatus	49.72	0.00e+00	657.00
IUUC-Ggo-045111	Gorilla gorilla	88.54	0.00e+00	1206.00
IUUC-Hsa-045695	Homo sapiens	88.54	0.00e+00	1204.00
IUUC-Hvu-047145	Hordeum vulgare	42.28	2.00e-23	103.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	47.94	2.00e-128	452.00
IUUC-Lch-050429	Latimeria chalumnae	52.40	0.00e+00	741.00
IUUC-Loc-051823	Lepisosteus oculatus	53.37	0.00e+00	664.00
IUUC-Lma-053145	Leptosphaeria maculans	32.24	2.00e-41	163.00
IUUC-Laf-053434	Loxodonta africana	87.94	0.00e+00	897.00
IUUC-Mcc-055249	Macaca mulatta	80.72	0.00e+00	766.00
IUUC-Meu-055901	Macropus eugenii	52.71	2.00e-100	360.00
IUUC-Mga-060131	Meleagris gallopavo	63.13	1.00e-180	625.00
IUUC-Mmr-060749	Microcebus murinus	90.96	0.00e+00	1256.00
IUUC-Mdo-062261	Monodelphis domestica	56.35	0.00e+00	754.00
IUUC-Mmu-063219	Mus musculus	81.81	0.00e+00	1102.00
IUUC-Mpu-066222	Mustela putorius furo	77.98	0.00e+00	1017.00
IUUC-Mlu-067769	Myotis lucifugus	86.03	0.00e+00	1162.00
IUUC-Nle-069738	Nomascus leucogenys	90.58	0.00e+00	972.00
IUUC-Ont-072029	Oreochromis niloticus	56.26	4.00e-172	598.00
IUUC-Oan-073179	Ornithorhynchus anatinus	81.10	2.00e-171	595.00
IUUC-Ocu-074884	Oryctolagus cuniculus	84.67	0.00e+00	1101.00
IUUC-Ogl-077658	Oryza glaberrima	32.98	1.00e-11	63.50
IUUC-Ome-081482	Oryza meridionalis	32.35	3.00e-11	62.80
IUUC-Osa-085978	Oryza sativa	32.98	2.00e-11	63.50
IUUC-Ola-086534	Oryzias latipes	42.70	5.00e-158	551.00
IUUC-Oga-089109	Otolemur garnettii	86.51	0.00e+00	1152.00
IUUC-Oar-089903	Ovis aries	91.44	0.00e+00	1199.00
IUUC-Ptr-091238	Pan troglodytes	87.98	0.00e+00	1191.00
IUUC-Pan-092379	Papio anubis	82.74	0.00e+00	1186.00
IUUC-Psi-093418	Pelodiscus sinensis	61.69	0.00e+00	726.00
IUUC-Pma-094231	Petromyzon marinus	62.87	7.00e-109	386.00
IUUC-Pno-094889	Phaeosphaeria nodorum	39.62	4.00e-42	165.00
IUUC-Pfo-097284	Poecilia formosa	49.64	5.00e-178	617.00
IUUC-Pab-098343	Pongo abelii	82.49	0.00e+00	1176.00
IUUC-Pca-100905	Procavia capensis	83.71	0.00e+00	1002.00
IUUC-Ppe-101621	Prunus persica	39.59	6.00e-35	141.00
IUUC-Pva-102242	Pteropus vampyrus	85.53	0.00e+00	1138.00
IUUC-Pgr-103289	Puccinia graminis	25.69	3.00e-25	110.00
IUUC-Ptt-103898	Puccinia triticina	27.15	3.00e-30	126.00
IUUC-Pte-104214	Pyrenophora teres	31.87	2.00e-39	157.00
IUUC-Pyt-104565	Pyrenophora triticirepentis	32.16	1.00e-39	157.00
IUUC-Rno-105899	Rattus norvegicus	77.57	0.00e+00	1098.00
IUUC-Sha-107565	Sarcophilus harrisii	51.54	0.00e+00	682.00
IUUC-Sja-107742	Schizosaccharomyces japonicus	36.89	8.00e-31	128.00
IUUC-Spo-108344	Schizosaccharomyces pombe	34.01	2.00e-24	106.00
IUUC-Sar-112999	Sorex araneus	63.42	0.00e+00	659.00
IUUC-Sre-114977	Sporisorium reilianum	33.33	9.00e-37	149.00
IUUC-Ssc-115705	Sus scrofa	92.76	0.00e+00	1250.00
IUUC-Tgu-116978	Taeniopygia guttata	65.90	0.00e+00	809.00
IUUC-Tru-118016	Takifugu rubripes	43.66	6.00e-154	537.00
IUUC-Tsy-118988	Tarsius syrichta	92.40	0.00e+00	934.00
IUUC-Tni-119913	Tetraodon nigroviridis	47.00	2.00e-161	562.00
IUUC-Tbe-127563	Tupaia belangeri	71.43	8.00e-144	503.00
IUUC-Ttr-128875	Tursiops truncatus	91.16	0.00e+00	1129.00
IUUC-Uma-129541	Ustilago maydis	46.40	6.00e-30	126.00
IUUC-Vpa-130779	Vicugna pacos	97.21	2.00e-161	561.00
IUUC-Xtr-132508	Xenopus tropicalis	52.57	0.00e+00	724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence