iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090380

Ensembl Protein ID

ENSOARP00000011201.1

UniProt Accession

W5PL78; W5PL78_SHEEP

Genbank Protein ID

ENSOARP00000011201

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01032945

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010441.1	ENSOART00000011361.1	ENSOARP00000011201.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.37	0.00e+00	1957.00	IUUC-Hsa-045964
E3 activity/RING/RING	87.92	0.00e+00	1892.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MAVSLPPTLG LSSAPDEIQH PHIKFSEWKF KLFRVRSFEK APENAQAEKQ DSSEGKPPLE 60
QSPAALDKAG GPKPALTQPP LKPHPKFLKK SHDDGKARDK AIHQANLRHL CRICGNSLKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTCT CTCTGCCACC CACCCTGGGA CTCAGTTCTG CCCCAGATGA AATCCAGCAT 60
CCACATATTA AATTTTCAGA ATGGAAATTT AAGCTGTTCA GGGTGAGATC CTTTGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

KEGG

oas:101107384

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	91.75	0.00e+00	1949.00
IUUC-Apl-003271	Anas platyrhynchos	76.89	0.00e+00	1680.00
IUUC-Aca-004400	Anolis carolinensis	74.64	0.00e+00	1638.00
IUUC-Ame-011295	Astyanax mexicanus	59.38	0.00e+00	1226.00
IUUC-Bta-012421	Bos taurus	98.14	0.00e+00	2055.00
IUUC-Cja-019891	Callithrix jacchus	90.51	0.00e+00	1901.00
IUUC-Cfa-020740	Canis familiaris	84.28	0.00e+00	1828.00
IUUC-Cpo-021800	Cavia porcellus	89.21	0.00e+00	1830.00
IUUC-Csa-024203	Chlorocebus sabaeus	90.29	0.00e+00	1713.00
IUUC-Dre-028416	Danio rerio	58.80	0.00e+00	1214.00
IUUC-Dno-029101	Dasypus novemcinctus	89.74	0.00e+00	1882.00
IUUC-Dse-031478	Dothistroma septosporum	28.67	2.00e-09	57.40
IUUC-Eca-033385	Equus caballus	92.43	0.00e+00	1957.00
IUUC-Fca-036545	Felis catus	90.89	0.00e+00	1935.00
IUUC-Fal-037208	Ficedula albicollis	75.58	0.00e+00	1664.00
IUUC-Gmo-039622	Gadus morhua	55.26	0.00e+00	1177.00
IUUC-Gga-041182	Gallus gallus	75.91	0.00e+00	1621.00
IUUC-Gac-041682	Gasterosteus aculeatus	57.46	0.00e+00	1211.00
IUUC-Ggo-044510	Gorilla gorilla	91.18	0.00e+00	1939.00
IUUC-Hsa-045964	Homo sapiens	91.37	0.00e+00	1942.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	91.37	0.00e+00	1931.00
IUUC-Lch-050041	Latimeria chalumnae	70.07	0.00e+00	1496.00
IUUC-Loc-052464	Lepisosteus oculatus	63.95	0.00e+00	1374.00
IUUC-Laf-053544	Loxodonta africana	89.93	0.00e+00	1914.00
IUUC-Mcc-054867	Macaca mulatta	90.80	0.00e+00	1930.00
IUUC-Meu-055986	Macropus eugenii	81.20	0.00e+00	1598.00
IUUC-Mga-059262	Meleagris gallopavo	76.64	0.00e+00	1637.00
IUUC-Mdo-062686	Monodelphis domestica	80.42	0.00e+00	1779.00
IUUC-Mmu-064297	Mus musculus	88.21	0.00e+00	1910.00
IUUC-Mpu-066027	Mustela putorius furo	91.18	0.00e+00	1920.00
IUUC-Mlu-067885	Myotis lucifugus	92.04	0.00e+00	1961.00
IUUC-Nle-070073	Nomascus leucogenys	90.99	0.00e+00	1934.00
IUUC-Ont-071400	Oreochromis niloticus	61.25	0.00e+00	1273.00
IUUC-Oan-072920	Ornithorhynchus anatinus	94.16	0.00e+00	780.00
IUUC-Ocu-074616	Oryctolagus cuniculus	90.51	0.00e+00	1906.00
IUUC-Ola-086828	Oryzias latipes	59.43	0.00e+00	1239.00
IUUC-Oga-088675	Otolemur garnettii	93.73	3.00e-154	536.00
IUUC-Ptr-090648	Pan troglodytes	91.47	0.00e+00	1947.00
IUUC-Pan-092036	Papio anubis	90.70	0.00e+00	1926.00
IUUC-Psi-093130	Pelodiscus sinensis	79.92	0.00e+00	1756.00
IUUC-Pfo-097273	Poecilia formosa	59.18	0.00e+00	1228.00
IUUC-Pca-100134	Procavia capensis	83.62	0.00e+00	1771.00
IUUC-Rno-105632	Rattus norvegicus	88.78	0.00e+00	1925.00
IUUC-Sha-107238	Sarcophilus harrisii	80.80	0.00e+00	1785.00
IUUC-Sar-113591	Sorex araneus	78.35	0.00e+00	1620.00
IUUC-Ssc-115720	Sus scrofa	92.33	0.00e+00	1961.00
IUUC-Tgu-117030	Taeniopygia guttata	76.18	0.00e+00	1644.00
IUUC-Tru-117669	Takifugu rubripes	57.03	0.00e+00	1149.00
IUUC-Tsy-119578	Tarsius syrichta	85.62	0.00e+00	1837.00
IUUC-Tni-120073	Tetraodon nigroviridis	57.44	0.00e+00	1187.00
IUUC-Tbe-128029	Tupaia belangeri	84.71	0.00e+00	970.00
IUUC-Ttr-128677	Tursiops truncatus	94.70	0.00e+00	818.00
IUUC-Vpa-130346	Vicugna pacos	95.94	0.00e+00	894.00
IUUC-Xtr-132442	Xenopus tropicalis	86.60	1.00e-100	358.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence