iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074616

Ensembl Protein ID

ENSOCUP00000020586.1

UniProt Accession

G1TU62; G1TU62_RABIT

Genbank Protein ID

ENSOCUP00000020586

Protein Name

V(D)J recombination-activating protein 1

Genbank Nucleotide ID

AAGW02037653

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000006989.2	ENSOCUT00000006985.2	ENSOCUP00000020586.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.29	0.00e+00	1947.00	IUUC-Hsa-045964
E3 activity/RING/RING	89.16	0.00e+00	1886.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAVSLPPTLG LSSAPDEIQH PHIKFSEWKF KLFRVRSFEK TTEENQKEKN SSEGKPSLEQ 60
SPAVLDKASG QKPEVAPPAF KVHPKFSKKF HDDGKARDKA IHQANLRHLC RICGNSLKTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTGT CTTTGCCACC AACCCTGGGA CTCAGCTCTG CCCCAGATGA AATTCAGCAT 60
CCACATATTA AATTTTCAGA ATGGAAATTT AAGCTATTCA GGGTGCGATC TTTTGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	91.75	0.00e+00	1941.00
IUUC-Apl-003271	Anas platyrhynchos	76.01	0.00e+00	1652.00
IUUC-Aca-004400	Anolis carolinensis	73.57	0.00e+00	1613.00
IUUC-Ame-011295	Astyanax mexicanus	58.64	0.00e+00	1210.00
IUUC-Bta-012421	Bos taurus	91.67	0.00e+00	1934.00
IUUC-Cja-019891	Callithrix jacchus	92.14	0.00e+00	1922.00
IUUC-Cfa-020740	Canis familiaris	83.60	0.00e+00	1817.00
IUUC-Cpo-021800	Cavia porcellus	90.66	0.00e+00	1852.00
IUUC-Csa-024203	Chlorocebus sabaeus	92.32	0.00e+00	1731.00
IUUC-Dre-028416	Danio rerio	58.91	0.00e+00	1204.00
IUUC-Dno-029101	Dasypus novemcinctus	91.08	0.00e+00	1899.00
IUUC-Eca-033385	Equus caballus	92.99	0.00e+00	1962.00
IUUC-Fca-036545	Felis catus	91.66	0.00e+00	1944.00
IUUC-Fal-037208	Ficedula albicollis	74.95	0.00e+00	1644.00
IUUC-Gmo-039622	Gadus morhua	54.81	0.00e+00	1180.00
IUUC-Gga-041182	Gallus gallus	75.63	0.00e+00	1603.00
IUUC-Gac-041682	Gasterosteus aculeatus	57.16	0.00e+00	1205.00
IUUC-Ggo-044510	Gorilla gorilla	93.38	0.00e+00	1963.00
IUUC-Hsa-045964	Homo sapiens	93.29	0.00e+00	1962.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	92.14	0.00e+00	1933.00
IUUC-Lch-050041	Latimeria chalumnae	70.16	0.00e+00	1474.00
IUUC-Loc-052464	Lepisosteus oculatus	64.19	0.00e+00	1371.00
IUUC-Laf-053544	Loxodonta africana	91.37	0.00e+00	1939.00
IUUC-Mcc-054867	Macaca mulatta	93.00	0.00e+00	1956.00
IUUC-Meu-055986	Macropus eugenii	81.94	0.00e+00	1597.00
IUUC-Mga-059262	Meleagris gallopavo	75.92	0.00e+00	1613.00
IUUC-Mdo-062686	Monodelphis domestica	81.38	0.00e+00	1779.00
IUUC-Mmu-064297	Mus musculus	89.35	0.00e+00	1939.00
IUUC-Mpu-066027	Mustela putorius furo	91.66	0.00e+00	1924.00
IUUC-Mlu-067885	Myotis lucifugus	92.71	0.00e+00	1960.00
IUUC-Nle-070073	Nomascus leucogenys	93.29	0.00e+00	1964.00
IUUC-Ont-071400	Oreochromis niloticus	61.46	0.00e+00	1275.00
IUUC-Oan-072920	Ornithorhynchus anatinus	94.42	0.00e+00	780.00
IUUC-Ola-086828	Oryzias latipes	60.11	0.00e+00	1252.00
IUUC-Oga-088675	Otolemur garnettii	94.46	9.00e-155	538.00
IUUC-Oar-090380	Ovis aries	90.89	0.00e+00	1935.00
IUUC-Ptr-090648	Pan troglodytes	93.48	0.00e+00	1966.00
IUUC-Pan-092036	Papio anubis	92.91	0.00e+00	1952.00
IUUC-Psi-093130	Pelodiscus sinensis	80.02	0.00e+00	1741.00
IUUC-Pfo-097273	Poecilia formosa	59.74	0.00e+00	1219.00
IUUC-Pca-100134	Procavia capensis	84.48	0.00e+00	1774.00
IUUC-Rno-105632	Rattus norvegicus	89.73	0.00e+00	1946.00
IUUC-Sha-107238	Sarcophilus harrisii	81.66	0.00e+00	1785.00
IUUC-Sar-113591	Sorex araneus	77.59	0.00e+00	1609.00
IUUC-Ssc-115720	Sus scrofa	91.28	0.00e+00	1912.00
IUUC-Tgu-117030	Taeniopygia guttata	75.59	0.00e+00	1627.00
IUUC-Tru-117669	Takifugu rubripes	56.15	0.00e+00	1147.00
IUUC-Tsy-119578	Tarsius syrichta	87.73	0.00e+00	1850.00
IUUC-Tni-120073	Tetraodon nigroviridis	57.38	0.00e+00	1189.00
IUUC-Tbe-128029	Tupaia belangeri	85.97	0.00e+00	967.00
IUUC-Ttr-128677	Tursiops truncatus	93.49	0.00e+00	803.00
IUUC-Vpa-130346	Vicugna pacos	95.03	0.00e+00	884.00
IUUC-Xtr-132442	Xenopus tropicalis	86.60	9.00e-101	358.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence