iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003960

Ensembl Protein ID

ENSAPLP00000011270.1

UniProt Accession

R0JLG7; R0JLG7_ANAPL

Genbank Protein ID

EOA98190.1

Protein Name

Rho guanine nucleotide exchange factor 6

Genbank Nucleotide ID

ADON01100106

Gene Name

ARHGEF6; Anapl_05269

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011391.1	ENSAPLT00000011994.1	ENSAPLP00000011270.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.30e-15	55.1	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL+ +kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVKARFNFKQTNEDELSVNKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 219
           68999*********************7..999*******..8**************997 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MNPEEQIVTW LISLGVLNSP KKIVDDPEEF LKTSLKDGTV LCRLINRLLP GSAEKYCLEP 60
KNEADCISNI QEFLKGCALL KVELFDPHDL YTGEQFSKVL STLTAVNKAT EDQPSKGPCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAGCAAAT TGTAACGTGG CTTATTTCCC TAGGAGTTCT GAATTCCCCT 60
AAGAAAATAG TAGATGATCC AGAGGAGTTC CTGAAAACTT CTCTGAAAGA TGGAACCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

apla:101805138

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	66.20	0.00e+00	1041.00
IUUC-Aca-004988	Anolis carolinensis	80.05	0.00e+00	1188.00
IUUC-Aly-005591	Arabidopsis lyrata	39.39	1.00e-09	57.00
IUUC-Ame-011546	Astyanax mexicanus	66.71	0.00e+00	963.00
IUUC-Bta-013527	Bos taurus	75.39	0.00e+00	1128.00
IUUC-Bdi-014394	Brachypodium distachyon	35.29	2.00e-08	52.80
IUUC-Cja-018935	Callithrix jacchus	75.39	0.00e+00	1115.00
IUUC-Cfa-021269	Canis familiaris	74.74	0.00e+00	1119.00
IUUC-Cpo-021620	Cavia porcellus	71.57	0.00e+00	1072.00
IUUC-Csa-023415	Chlorocebus sabaeus	75.39	0.00e+00	1123.00
IUUC-Cho-024736	Choloepus hoffmanni	72.22	2.00e-59	223.00
IUUC-Cin-025535	Ciona intestinalis	42.50	7.00e-82	297.00
IUUC-Cne-026866	Cryptococcus neoformans	52.94	1.00e-12	69.30
IUUC-Dre-028580	Danio rerio	66.06	0.00e+00	993.00
IUUC-Dno-029201	Dasypus novemcinctus	71.83	0.00e+00	1100.00
IUUC-Dor-030868	Dipodomys ordii	62.11	0.00e+00	841.00
IUUC-Dme-032219	Drosophila melanogaster	44.09	1.00e-94	341.00
IUUC-Ete-032236	Echinops telfairi	54.32	7.00e-144	503.00
IUUC-Eca-033500	Equus caballus	75.90	0.00e+00	1124.00
IUUC-Eeu-035269	Erinaceus europaeus	66.76	5.00e-132	464.00
IUUC-Fca-035683	Felis catus	74.48	0.00e+00	1101.00
IUUC-Fal-037611	Ficedula albicollis	94.05	0.00e+00	1411.00
IUUC-Gmo-038980	Gadus morhua	63.47	0.00e+00	927.00
IUUC-Gga-040940	Gallus gallus	95.60	0.00e+00	1445.00
IUUC-Gac-042203	Gasterosteus aculeatus	63.93	0.00e+00	965.00
IUUC-Ggo-044755	Gorilla gorilla	75.26	0.00e+00	1118.00
IUUC-Hsa-046210	Homo sapiens	75.00	0.00e+00	1116.00
IUUC-Hvu-047839	Hordeum vulgare	36.63	1.00e-08	52.00
IUUC-Lch-049517	Latimeria chalumnae	74.07	0.00e+00	1099.00
IUUC-Loc-052393	Lepisosteus oculatus	66.92	0.00e+00	1024.00
IUUC-Laf-054196	Loxodonta africana	75.48	0.00e+00	1098.00
IUUC-Mcc-055716	Macaca mulatta	75.26	0.00e+00	1120.00
IUUC-Meu-056285	Macropus eugenii	69.98	0.00e+00	638.00
IUUC-Mtr-058576	Medicago truncatula	43.42	1.00e-12	66.60
IUUC-Mga-060029	Meleagris gallopavo	96.25	0.00e+00	1462.00
IUUC-Mmr-060803	Microcebus murinus	75.52	0.00e+00	1121.00
IUUC-Mdo-062654	Monodelphis domestica	78.02	0.00e+00	1152.00
IUUC-Mmu-063479	Mus musculus	73.71	0.00e+00	1086.00
IUUC-Mpu-066065	Mustela putorius furo	74.74	0.00e+00	1095.00
IUUC-Mlu-068222	Myotis lucifugus	74.00	0.00e+00	1084.00
IUUC-Nle-069379	Nomascus leucogenys	75.26	0.00e+00	1118.00
IUUC-Opr-070687	Ochotona princeps	58.55	0.00e+00	648.00
IUUC-Ont-072240	Oreochromis niloticus	60.02	0.00e+00	921.00
IUUC-Oan-073067	Ornithorhynchus anatinus	81.83	0.00e+00	1238.00
IUUC-Ocu-074852	Oryctolagus cuniculus	74.10	0.00e+00	1097.00
IUUC-Oba-075543	Oryza barthii	34.29	1.70e+00	27.30
IUUC-Ogu-078135	Oryza glumaepatula	34.29	1.70e+00	27.30
IUUC-Oni-082520	Oryza nivara	34.29	6.10e-01	28.10
IUUC-Opu-083443	Oryza punctata	34.29	1.10e+00	27.30
IUUC-Oru-085261	Oryza rufipogon	34.29	1.60e+00	27.30
IUUC-Osa-085322	Oryza sativa	34.29	1.70e+00	27.30
IUUC-Ola-086663	Oryzias latipes	58.12	0.00e+00	660.00
IUUC-Oga-089048	Otolemur garnettii	69.22	0.00e+00	942.00
IUUC-Oar-089339	Ovis aries	75.39	0.00e+00	1127.00
IUUC-Ptr-091162	Pan troglodytes	58.15	0.00e+00	712.00
IUUC-Pan-092666	Papio anubis	73.52	0.00e+00	1074.00
IUUC-Psi-093116	Pelodiscus sinensis	87.31	0.00e+00	1334.00
IUUC-Pma-094701	Petromyzon marinus	56.86	5.00e-115	407.00
IUUC-Pfo-097394	Poecilia formosa	64.36	0.00e+00	963.00
IUUC-Pab-098567	Pongo abelii	75.26	0.00e+00	1118.00
IUUC-Pca-100997	Procavia capensis	65.81	0.00e+00	904.00
IUUC-Pva-102500	Pteropus vampyrus	73.84	0.00e+00	1070.00
IUUC-Rno-104974	Rattus norvegicus	73.52	0.00e+00	1061.00
IUUC-Sha-106845	Sarcophilus harrisii	61.64	0.00e+00	807.00
IUUC-Sly-111123	Solanum lycopersicum	38.10	2.00e-09	55.80
IUUC-Sar-113420	Sorex araneus	73.45	0.00e+00	1058.00
IUUC-Ssc-115679	Sus scrofa	75.29	0.00e+00	981.00
IUUC-Tgu-117069	Taeniopygia guttata	93.55	0.00e+00	1409.00
IUUC-Tru-118488	Takifugu rubripes	58.43	0.00e+00	840.00
IUUC-Tsy-119243	Tarsius syrichta	68.54	0.00e+00	768.00
IUUC-Tni-120584	Tetraodon nigroviridis	62.50	0.00e+00	922.00
IUUC-Tbe-127994	Tupaia belangeri	61.60	0.00e+00	895.00
IUUC-Ttr-128839	Tursiops truncatus	74.23	0.00e+00	1084.00
IUUC-Vpa-130144	Vicugna pacos	70.42	0.00e+00	988.00
IUUC-Xtr-132624	Xenopus tropicalis	72.14	0.00e+00	1105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence