iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117995

UUCD1 version

UUC-TaR-01136

Ensembl Protein ID

ENSTRUP00000033448.1

UniProt Accession

H2U932; H2U932_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013149.1	ENSTRUT00000033574.1	ENSTRUP00000033448.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-93	314.4	9	637

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgye 88
           GlkN+gNtC+mN+v+QcLsn+  l+e+l     e+     p+   ge++++l++l+++lw  +++ +     ++ ++++k+a++f+g++
   Q: 9    GLKNHGNTCFMNAVVQCLSNTDLLAEYLGL---EQY---RPDAARGEVTEHLASLVRALWtlEYTPQLSVEFKFRSTVAKYASQFRGNS 91
           9**************************988...333...3456789**************9988888999999**************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           q+Da Efl +lld+++e++++ +++  +++ +++ ++++    ++ ++++  +s++++ Fq q++s+++c++c ++s++++pfl +slp
   Q: 92   QHDALEFLLWLLDRVHEDVNEISSNAPNSTPQKAWISSQIFtsSSTSQPRDRHSFVQEHFQAQYRSSLTCPHCLKQSNTFDPFLCISLP 180
           *******************9988888887777776666655446777888888************************************ PP
   S: 176  vpgkeetkke............................................................................... 185
           +p ++++++                                                                                
   Q: 181  IPLRQTRSMCvtlvfntkgqrylrvglavplfgsvsnlrsmvaeegsissnqvilaelyssgfqrsfsdeddltaigdsdvvyafqapp 269
           *****887669****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 270  lhshgssasshsgkllsdcstaspegqrlppsgtlssdylnqggsskvlllicntagggqqavrfgppflmhedrnisweqlqqsilsk 358
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 359  lyylmlngsqaqnagklfrirvvggsaaysylspqdsrplhhpavdralklcgtggpphtklviewenktkeclfgniqeevvkdaesv 447
           ***************************************************************************************** PP
   S: 186  .............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
                        +l++c++ +tkee+l  +++++c++ck++q+   k++l++lP++LilhLkRf  ++ +++r+k+++ v fp   Ld
   Q: 448  rnqqqqhlqqhscTLDECFQLYTKEEQLAPDDAWKCPHCKQLQQGMVKMSLWTLPDILILHLKRF--RQVGERRNKLSTPVRFPMAgLD 534
           *****************************************************************..9999****************** PP
   S: 261  lspfctspeekqke...........................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeee 321
           ++p+++++++++k+                           ++ Y+L+av++H+G++++GHY+ay++n  +g+W+ +dDs+V  ++eee
   Q: 535  MAPHVVKRSQSVKNvntgawppswkqssgkqqqpadlilprDYLYDLYAVCNHHGGMHGGHYTAYCRNsVDGQWYSYDDSSVDLIPEEE 623
           *******888888899999999999999999*************************************55777**************** PP
   S: 322  vleetgstaYvlfYkrr 338
           v++   + aY+lfY+rr
   Q: 624  VCT---RGAYILFYERR 637
           ***...********996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

GDKTPGVLGL KNHGNTCFMN AVVQCLSNTD LLAEYLGLEQ YRPDAARGEV TEHLASLVRA 60
LWTLEYTPQL SVEFKFRSTV AKYASQFRGN SQHDALEFLL WLLDRVHEDV NEISSNAPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGACAAAA CTCCCGGGGT GCTGGGACTA AAGAACCACG GCAACACCTG CTTCATGAAC 60
GCCGTGGTCC AGTGCCTGAG CAACACGGAC CTGCTCGCGG AGTACCTCGG TCTGGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	48.83	0.00e+00	759.00
IUUC-Aca-004436	Anolis carolinensis	53.30	0.00e+00	795.00
IUUC-Ame-011153	Astyanax mexicanus	58.17	0.00e+00	1071.00
IUUC-Bta-013560	Bos taurus	63.49	0.00e+00	898.00
IUUC-Cja-018737	Callithrix jacchus	52.35	0.00e+00	884.00
IUUC-Cfa-020347	Canis familiaris	50.28	0.00e+00	835.00
IUUC-Csa-023656	Chlorocebus sabaeus	53.41	0.00e+00	918.00
IUUC-Cho-024864	Choloepus hoffmanni	50.29	4.00e-155	541.00
IUUC-Dre-028066	Danio rerio	60.11	0.00e+00	1169.00
IUUC-Dno-028855	Dasypus novemcinctus	58.96	0.00e+00	802.00
IUUC-Dor-030475	Dipodomys ordii	64.41	3.00e-136	479.00
IUUC-Eca-034147	Equus caballus	62.18	0.00e+00	872.00
IUUC-Fca-036550	Felis catus	48.10	0.00e+00	673.00
IUUC-Gmo-038903	Gadus morhua	58.33	0.00e+00	797.00
IUUC-Gac-042087	Gasterosteus aculeatus	71.67	0.00e+00	1334.00
IUUC-Ggo-045171	Gorilla gorilla	53.23	0.00e+00	918.00
IUUC-Hsa-045961	Homo sapiens	53.22	0.00e+00	921.00
IUUC-Loc-052852	Lepisosteus oculatus	74.50	0.00e+00	1138.00
IUUC-Laf-054033	Loxodonta africana	50.23	0.00e+00	833.00
IUUC-Mcc-055431	Macaca mulatta	52.99	0.00e+00	917.00
IUUC-Mmr-061035	Microcebus murinus	52.49	0.00e+00	880.00
IUUC-Mdo-062172	Monodelphis domestica	57.91	0.00e+00	780.00
IUUC-Mmu-063966	Mus musculus	59.51	0.00e+00	847.00
IUUC-Mpu-066307	Mustela putorius furo	58.14	0.00e+00	786.00
IUUC-Nle-070172	Nomascus leucogenys	63.41	0.00e+00	902.00
IUUC-Opr-070499	Ochotona princeps	62.46	0.00e+00	754.00
IUUC-Ont-071920	Oreochromis niloticus	72.25	0.00e+00	1400.00
IUUC-Ocu-074014	Oryctolagus cuniculus	60.41	0.00e+00	760.00
IUUC-Ola-086360	Oryzias latipes	67.57	0.00e+00	1285.00
IUUC-Oga-088202	Otolemur garnettii	51.59	0.00e+00	874.00
IUUC-Oar-089819	Ovis aries	63.16	0.00e+00	833.00
IUUC-Ptr-091076	Pan troglodytes	53.13	0.00e+00	920.00
IUUC-Pan-092248	Papio anubis	52.89	0.00e+00	910.00
IUUC-Pfo-096534	Poecilia formosa	68.31	0.00e+00	1228.00
IUUC-Pab-098453	Pongo abelii	52.73	0.00e+00	880.00
IUUC-Pca-100290	Procavia capensis	48.93	2.00e-90	327.00
IUUC-Pva-102317	Pteropus vampyrus	53.19	0.00e+00	712.00
IUUC-Rno-104948	Rattus norvegicus	59.77	0.00e+00	764.00
IUUC-Sha-106558	Sarcophilus harrisii	59.26	0.00e+00	852.00
IUUC-Sar-113105	Sorex araneus	53.15	4.00e-180	625.00
IUUC-Ssc-115312	Sus scrofa	51.71	0.00e+00	886.00
IUUC-Tni-120517	Tetraodon nigroviridis	76.18	0.00e+00	1408.00
IUUC-Tbe-127439	Tupaia belangeri	53.14	3.00e-44	173.00
IUUC-Vpa-130306	Vicugna pacos	54.79	5.00e-112	399.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence