iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-066953

Ensembl Protein ID

ENSMLUP00000011369.2

UniProt Accession

G1PKN2; G1PKN2_MYOLU

Genbank Protein ID

ENSMLUP00000011369

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02043930

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012490.2	ENSMLUT00000012491.2	ENSMLUP00000011369.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.46	0.00e+00	681.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

DFIMWASCCN WFCVDGQPEE AAPPQGARAQ AYSNPGYSSF PSPTGSEPSC KACGAHFANM 60
ARKQTCLDCK KNFCMTCSSQ VGNGPRLCLL CQRFRATAFQ REELMKMKVK DLRDYLNLHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTTTATCA TGTGGGCAAG CTGTTGCAAC TGGTTCTGCG TGGATGGACA GCCTGAGGAG 60
GCCGCACCAC CCCAGGGAGC CAGGGCGCAG GCCTATTCCA ATCCTGGGTA CAGCTCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000777	Aegilops tauschii	31.82	5.00e-07	50.40
IUUC-Aml-001630	Ailuropoda melanoleuca	90.98	0.00e+00	652.00
IUUC-Apl-004124	Anas platyrhynchos	66.30	2.00e-123	435.00
IUUC-Ame-011616	Astyanax mexicanus	58.63	8.00e-106	376.00
IUUC-Bta-012374	Bos taurus	87.70	0.00e+00	649.00
IUUC-Cja-019780	Callithrix jacchus	89.29	0.00e+00	662.00
IUUC-Cfa-021252	Canis familiaris	93.44	0.00e+00	659.00
IUUC-Cpo-022047	Cavia porcellus	88.80	0.00e+00	652.00
IUUC-Csa-023161	Chlorocebus sabaeus	90.91	0.00e+00	699.00
IUUC-Cho-024316	Choloepus hoffmanni	90.43	1.00e-156	545.00
IUUC-Dre-028596	Danio rerio	55.65	7.00e-111	393.00
IUUC-Dno-029333	Dasypus novemcinctus	91.74	0.00e+00	665.00
IUUC-Ete-033163	Echinops telfairi	82.92	4.00e-165	573.00
IUUC-Eca-033994	Equus caballus	92.35	0.00e+00	683.00
IUUC-Eeu-035162	Erinaceus europaeus	87.00	5.00e-132	463.00
IUUC-Fca-036418	Felis catus	91.26	0.00e+00	703.00
IUUC-Fal-037427	Ficedula albicollis	67.58	3.00e-134	471.00
IUUC-Gga-041053	Gallus gallus	67.77	2.00e-132	465.00
IUUC-Ggo-045436	Gorilla gorilla	91.46	0.00e+00	702.00
IUUC-Hsa-045798	Homo sapiens	91.46	0.00e+00	702.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	88.25	0.00e+00	631.00
IUUC-Lch-050639	Latimeria chalumnae	61.43	8.00e-126	443.00
IUUC-Laf-053355	Loxodonta africana	86.68	2.00e-178	618.00
IUUC-Mcc-055222	Macaca mulatta	90.36	0.00e+00	652.00
IUUC-Meu-056692	Macropus eugenii	76.86	3.00e-156	544.00
IUUC-Mga-059298	Meleagris gallopavo	67.40	9.00e-133	466.00
IUUC-Mmr-061792	Microcebus murinus	88.71	0.00e+00	636.00
IUUC-Mdo-062986	Monodelphis domestica	79.73	5.00e-167	580.00
IUUC-Mmu-063356	Mus musculus	87.70	0.00e+00	645.00
IUUC-Mac-064492	Musa acuminata	36.36	6.00e-07	49.70
IUUC-Mpu-066273	Mustela putorius furo	92.90	0.00e+00	714.00
IUUC-Nle-070075	Nomascus leucogenys	90.71	0.00e+00	704.00
IUUC-Opr-070838	Ochotona princeps	88.71	0.00e+00	640.00
IUUC-Ont-071967	Oreochromis niloticus	74.13	6.00e-55	207.00
IUUC-Ocu-074807	Oryctolagus cuniculus	89.34	0.00e+00	685.00
IUUC-Ola-086903	Oryzias latipes	51.19	5.00e-91	327.00
IUUC-Oga-088536	Otolemur garnettii	87.88	2.00e-178	618.00
IUUC-Oar-089838	Ovis aries	86.61	0.00e+00	630.00
IUUC-Ptr-090962	Pan troglodytes	91.74	0.00e+00	702.00
IUUC-Pan-092853	Papio anubis	90.36	0.00e+00	695.00
IUUC-Psi-093164	Pelodiscus sinensis	69.04	7.00e-125	440.00
IUUC-Pma-094104	Petromyzon marinus	45.25	4.00e-55	208.00
IUUC-Pno-094968	Phaeosphaeria nodorum	38.78	1.00e-08	56.60
IUUC-Pab-098304	Pongo abelii	91.26	0.00e+00	706.00
IUUC-Pop-099791	Populus trichocarpa	35.06	7.00e-08	52.80
IUUC-Pca-100316	Procavia capensis	89.81	1.00e-179	622.00
IUUC-Ppe-101490	Prunus persica	36.59	2.00e-08	53.50
IUUC-Pva-102612	Pteropus vampyrus	78.79	1.00e-160	558.00
IUUC-Rno-105449	Rattus norvegicus	87.88	0.00e+00	635.00
IUUC-Sha-107578	Sarcophilus harrisii	78.63	8.00e-155	539.00
IUUC-Sit-110649	Setaria italica	37.14	1.00e-08	52.00
IUUC-Sar-113638	Sorex araneus	87.88	6.00e-179	619.00
IUUC-Ssc-116401	Sus scrofa	91.26	0.00e+00	700.00
IUUC-Tru-118765	Takifugu rubripes	50.55	2.00e-83	302.00
IUUC-Tsy-118850	Tarsius syrichta	88.78	5.00e-154	536.00
IUUC-Tae-124586	Triticum aestivum	40.00	3.00e-07	50.10
IUUC-Tbe-128086	Tupaia belangeri	82.64	3.00e-179	620.00
IUUC-Ttr-128249	Tursiops truncatus	70.52	3.00e-140	491.00
IUUC-Vpa-130816	Vicugna pacos	87.21	9.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence