iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004628

Ensembl Protein ID

ENSACAP00000014580.3

UniProt Accession

H9GLK6; H9GLK6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

VAV2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000014720.3	ENSACAT00000014875.3	ENSACAP00000014580.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.40e-11	42.5	702	753

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 702  ARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKG--ETNGRIGWFPSTYVEE 753
           67**********************************..9*************86 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSQVISAVSR LSYHTIAQNK GIRPFPSEET TQNDDDVYRS LEELADEHDL GEDIYDCVPC 60
EDEGDDIYED IIKVEVQQPM KMGMTEDDKR NCCLLEIQET EAKYYKTLEE IEKNYMNPLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGT GGCGGCAGTG CGGGCGCTGG CTCATCGACT GCAAGGTGCT GCCGGCCAAC 60
CACCGGGTGG TGTGGCCCTC GGCCGTGGTC TTCGAGCTGG CCCAGGCCCT CCGCGACGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0030032--P:lamellipodium assembly
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0030193--P:regulation of blood coagulation
GO:0008361--P:regulation of cell size
GO:0010468--P:regulation of gene expression
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003262	Anas platyrhynchos	68.08	0.00e+00	934.00
IUUC-Ath-007352	Arabidopsis thaliana	41.18	1.00e-03	38.50
IUUC-Bta-013147	Bos taurus	64.85	0.00e+00	838.00
IUUC-Cja-018877	Callithrix jacchus	63.71	0.00e+00	864.00
IUUC-Cfa-020315	Canis familiaris	64.10	0.00e+00	800.00
IUUC-Cpo-021543	Cavia porcellus	88.15	0.00e+00	760.00
IUUC-Csa-024204	Chlorocebus sabaeus	64.44	0.00e+00	904.00
IUUC-Dno-029584	Dasypus novemcinctus	61.30	0.00e+00	753.00
IUUC-Dor-031014	Dipodomys ordii	74.42	0.00e+00	694.00
IUUC-Eeu-035182	Erinaceus europaeus	77.53	1.00e-164	573.00
IUUC-Fca-035460	Felis catus	69.90	0.00e+00	761.00
IUUC-Fal-036684	Ficedula albicollis	65.92	0.00e+00	910.00
IUUC-Gmo-038816	Gadus morhua	60.13	0.00e+00	772.00
IUUC-Gga-040999	Gallus gallus	68.66	0.00e+00	941.00
IUUC-Gac-041353	Gasterosteus aculeatus	62.23	0.00e+00	838.00
IUUC-Ggo-044558	Gorilla gorilla	65.65	0.00e+00	912.00
IUUC-Hsa-046208	Homo sapiens	65.78	0.00e+00	913.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	61.64	0.00e+00	780.00
IUUC-Mcc-055054	Macaca mulatta	65.78	0.00e+00	912.00
IUUC-Mga-060106	Meleagris gallopavo	68.08	0.00e+00	929.00
IUUC-Mmr-061118	Microcebus murinus	65.59	0.00e+00	899.00
IUUC-Mdo-062380	Monodelphis domestica	67.10	0.00e+00	892.00
IUUC-Mmu-063135	Mus musculus	66.71	0.00e+00	920.00
IUUC-Mpu-066135	Mustela putorius furo	66.62	0.00e+00	917.00
IUUC-Oan-073384	Ornithorhynchus anatinus	67.21	0.00e+00	861.00
IUUC-Oga-088444	Otolemur garnettii	66.18	0.00e+00	885.00
IUUC-Oar-089576	Ovis aries	61.83	0.00e+00	778.00
IUUC-Ptr-090507	Pan troglodytes	66.50	0.00e+00	918.00
IUUC-Pan-092325	Papio anubis	66.49	0.00e+00	918.00
IUUC-Psi-094021	Pelodiscus sinensis	68.15	0.00e+00	923.00
IUUC-Pca-100295	Procavia capensis	65.22	0.00e+00	904.00
IUUC-Rno-105332	Rattus norvegicus	66.24	0.00e+00	907.00
IUUC-Sha-106529	Sarcophilus harrisii	65.72	0.00e+00	816.00
IUUC-Ssc-116176	Sus scrofa	65.01	0.00e+00	899.00
IUUC-Tgu-116917	Taeniopygia guttata	91.52	0.00e+00	813.00
IUUC-Tru-118398	Takifugu rubripes	56.74	0.00e+00	632.00
IUUC-Tni-120819	Tetraodon nigroviridis	61.44	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence