iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024134

Ensembl Protein ID

ENSCSAP00000000443.1

UniProt Accession

A0A0D9QVQ4; A0A0D9QVQ4_CHLSB

Genbank Protein ID

ENSCSAP00000000443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01134169

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004094.1	ENSCSAT00000002116.1	ENSCSAP00000000443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-28	98.0	337	367
UBD/Beta-Prp	1.30e-45	155.8	335	620

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f ++  ll++G+ D  i++W++
   Q: 337  HLSEVNAVRFgPNsSLLATGGADRLIHLWNV 367
           99*********7779***************7 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v    l   ++l+g  + +t+v+f+p+g   + +   +++++w +   +   tl+gh
   Q: 335  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLevNQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGH 423
           789999****************************9999888999****************888888889******************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 424  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGR 506
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iWd+++g+l + lq+++ +
   Q: 507  VTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSYDGALYIWDVDTGKLESRLQGPHCT 594
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 595  AVNAVAWCYSGSHVVSVDQGRKVVLW 620
           7777778************99**999 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAGPGVPGAP VARWKRHIVW QLRLRDRTQK ALFLELVPAY NHLLEKAELL DKFSKKLQPE 60
PNSVTPTTHQ GPWEESGLDS DQVPSLATLR VKWQEEEEGL RLVCGEMAYQ VVEKSVALGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGCCATG GCTGGGCCCG GCGTCCCCGG CGCCCCCGTA GCCCGATGGA AACGCCACAT 60
TGTGTGGCAG CTGCGTCTTC GGGACCGTAC GCAAAAGGCG CTCTTCCTGG AGCTGGTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	69.17	0.00e+00	762.00
IUUC-Ame-011152	Astyanax mexicanus	41.90	1.00e-114	406.00
IUUC-Bta-013118	Bos taurus	84.70	0.00e+00	937.00
IUUC-Cja-020002	Callithrix jacchus	89.39	0.00e+00	1005.00
IUUC-Cfa-020878	Canis familiaris	82.60	0.00e+00	925.00
IUUC-Cpo-022476	Cavia porcellus	82.52	0.00e+00	899.00
IUUC-Cho-024853	Choloepus hoffmanni	70.35	7.00e-177	613.00
IUUC-Dre-027949	Danio rerio	42.23	7.00e-126	444.00
IUUC-Dno-029683	Dasypus novemcinctus	84.37	0.00e+00	775.00
IUUC-Dor-030897	Dipodomys ordii	77.26	0.00e+00	926.00
IUUC-Ete-032957	Echinops telfairi	93.23	1.00e-131	463.00
IUUC-Eca-033303	Equus caballus	90.12	1.00e-163	568.00
IUUC-Eeu-035336	Erinaceus europaeus	74.19	6.00e-154	537.00
IUUC-Fca-036232	Felis catus	85.05	0.00e+00	1000.00
IUUC-Gmo-038880	Gadus morhua	50.35	2.00e-71	263.00
IUUC-Gac-042500	Gasterosteus aculeatus	40.68	3.00e-93	335.00
IUUC-Ggo-045130	Gorilla gorilla	96.77	0.00e+00	737.00
IUUC-Hsa-046359	Homo sapiens	95.07	0.00e+00	1004.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	85.62	0.00e+00	965.00
IUUC-Lch-050669	Latimeria chalumnae	54.52	3.00e-96	345.00
IUUC-Loc-052789	Lepisosteus oculatus	43.20	4.00e-111	395.00
IUUC-Laf-053699	Loxodonta africana	84.53	0.00e+00	934.00
IUUC-Mcc-055657	Macaca mulatta	91.79	0.00e+00	966.00
IUUC-Meu-056639	Macropus eugenii	47.86	2.00e-106	379.00
IUUC-Mmr-061314	Microcebus murinus	79.97	0.00e+00	856.00
IUUC-Mdo-061841	Monodelphis domestica	63.19	0.00e+00	686.00
IUUC-Mmu-064065	Mus musculus	82.10	0.00e+00	939.00
IUUC-Mpu-066742	Mustela putorius furo	82.93	0.00e+00	906.00
IUUC-Mlu-067019	Myotis lucifugus	88.34	0.00e+00	677.00
IUUC-Nle-069037	Nomascus leucogenys	95.07	0.00e+00	1057.00
IUUC-Opr-071039	Ochotona princeps	81.32	0.00e+00	899.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.91	6.00e-139	486.00
IUUC-Ocu-074772	Oryctolagus cuniculus	83.45	0.00e+00	835.00
IUUC-Ola-086964	Oryzias latipes	52.96	1.00e-83	302.00
IUUC-Oga-088188	Otolemur garnettii	86.15	0.00e+00	899.00
IUUC-Oar-090231	Ovis aries	78.80	0.00e+00	914.00
IUUC-Ptr-091434	Pan troglodytes	92.62	0.00e+00	961.00
IUUC-Pan-091868	Papio anubis	98.07	0.00e+00	1061.00
IUUC-Psi-093652	Pelodiscus sinensis	66.09	1.00e-163	569.00
IUUC-Pfo-096960	Poecilia formosa	42.83	7.00e-102	364.00
IUUC-Pab-097776	Pongo abelii	93.92	0.00e+00	964.00
IUUC-Pca-100220	Procavia capensis	64.90	2.00e-179	622.00
IUUC-Pva-103135	Pteropus vampyrus	86.06	0.00e+00	878.00
IUUC-Rno-105529	Rattus norvegicus	80.80	0.00e+00	969.00
IUUC-Sha-107062	Sarcophilus harrisii	62.66	0.00e+00	716.00
IUUC-Sar-113109	Sorex araneus	66.83	4.00e-133	468.00
IUUC-Ssc-115271	Sus scrofa	85.71	0.00e+00	922.00
IUUC-Ttr-128267	Tursiops truncatus	81.16	0.00e+00	877.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence