iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045130

Ensembl Protein ID

ENSGGOP00000003418.2

UniProt Accession

G3QLQ6; G3QLQ6_GORGO

Protein Name

Uncharacterized protein

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003472.2	ENSGGOT00000003495.2	ENSGGOP00000003418.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-29	100.5	226	256
UBD/Beta-Prp	1.50e-46	159.3	224	510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f ++  ll++G+ D  i++W++
   Q: 226  HLSEVNAVRFgPNsSLLATGGADRLIHLWNV 256
           99*********7779***************7 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v    l   ++l+g  + +t+v+f+p+g   + +   +++++w +   +   tl+gh
   Q: 224  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLeaNQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGH 312
           6899999****************************99988899*****************888888889******************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 313  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGR 395
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs+Dg ++iWd+++g+l + lq+++  
   Q: 396  VTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCA 483
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniwk 293
            +   +++++++++v++++  kv +w+
   Q: 484  AVNAVAWCYSGSHMVSVDQGRKVVLWQ 510
           7777778****************9995 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAGPGVPGAP AARWKRHIVR QLRLRDRTQK ALFLELVPAY NHLLEKAELL DKFSKKLQPE 60
PNSVTPTTHQ GPWEESELDS DQVPSLVALR VKWQEEEEGL RLVCGEAKQA RVSQELKKAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGGC CGGGCGTCCC CGGTGCCCCC GCAGCGCGCT GGAAACGCCA CATCGTGCGG 60
CAGCTGCGGC TTCGGGACCG TACGCAAAAG GCGCTTTTCC TGGAGCTGGT GCCGGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	76.33	8.00e-170	590.00
IUUC-Atr-003073	Amborella trichopoda	31.76	9.00e-27	114.00
IUUC-Aca-004664	Anolis carolinensis	72.05	3.00e-98	350.00
IUUC-Ame-011152	Astyanax mexicanus	54.86	2.00e-100	359.00
IUUC-Bta-013118	Bos taurus	89.80	0.00e+00	706.00
IUUC-Cja-020002	Callithrix jacchus	93.10	0.00e+00	715.00
IUUC-Cfa-020878	Canis familiaris	86.43	0.00e+00	702.00
IUUC-Cpo-022476	Cavia porcellus	88.16	0.00e+00	704.00
IUUC-Csa-024134	Chlorocebus sabaeus	96.52	0.00e+00	767.00
IUUC-Cho-024853	Choloepus hoffmanni	71.53	5.00e-162	563.00
IUUC-Dno-029683	Dasypus novemcinctus	89.33	0.00e+00	711.00
IUUC-Dor-030897	Dipodomys ordii	85.61	0.00e+00	754.00
IUUC-Ete-032957	Echinops telfairi	93.23	2.00e-130	459.00
IUUC-Eca-033303	Equus caballus	90.12	2.00e-161	561.00
IUUC-Eeu-035336	Erinaceus europaeus	73.76	2.00e-152	532.00
IUUC-Fca-036232	Felis catus	89.30	0.00e+00	744.00
IUUC-Gmo-038880	Gadus morhua	50.35	6.00e-71	261.00
IUUC-Gac-042500	Gasterosteus aculeatus	44.94	3.00e-82	299.00
IUUC-Hsa-046359	Homo sapiens	99.50	0.00e+00	751.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	92.98	0.00e+00	732.00
IUUC-Lch-050669	Latimeria chalumnae	54.22	2.00e-94	338.00
IUUC-Laf-053699	Loxodonta africana	93.02	0.00e+00	733.00
IUUC-Mcc-055657	Macaca mulatta	91.54	0.00e+00	675.00
IUUC-Meu-056639	Macropus eugenii	49.75	8.00e-96	344.00
IUUC-Mmr-061314	Microcebus murinus	81.39	3.00e-172	598.00
IUUC-Mdo-061841	Monodelphis domestica	74.69	1.00e-174	606.00
IUUC-Mmu-064065	Mus musculus	89.25	0.00e+00	737.00
IUUC-Mpu-066742	Mustela putorius furo	86.32	0.00e+00	694.00
IUUC-Mlu-067019	Myotis lucifugus	88.34	0.00e+00	671.00
IUUC-Nle-069037	Nomascus leucogenys	98.51	0.00e+00	744.00
IUUC-Opr-071039	Ochotona princeps	88.56	0.00e+00	723.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.22	4.00e-138	484.00
IUUC-Ocu-074772	Oryctolagus cuniculus	90.20	0.00e+00	693.00
IUUC-Ola-086964	Oryzias latipes	52.61	2.00e-83	301.00
IUUC-Oga-088188	Otolemur garnettii	88.38	0.00e+00	683.00
IUUC-Oar-090231	Ovis aries	89.02	0.00e+00	705.00
IUUC-Ptr-091434	Pan troglodytes	99.25	0.00e+00	746.00
IUUC-Pan-091868	Papio anubis	97.02	0.00e+00	735.00
IUUC-Psi-093652	Pelodiscus sinensis	65.69	7.00e-163	566.00
IUUC-Pfo-096960	Poecilia formosa	48.14	4.00e-87	315.00
IUUC-Pab-097776	Pongo abelii	98.51	0.00e+00	780.00
IUUC-Pca-100220	Procavia capensis	65.84	4.00e-123	435.00
IUUC-Pva-103135	Pteropus vampyrus	91.32	0.00e+00	704.00
IUUC-Rno-105529	Rattus norvegicus	87.44	0.00e+00	730.00
IUUC-Sha-107062	Sarcophilus harrisii	71.13	2.00e-175	608.00
IUUC-Sar-113109	Sorex araneus	62.42	2.00e-138	485.00
IUUC-Ssc-115271	Sus scrofa	89.28	0.00e+00	684.00
IUUC-Tni-120373	Tetraodon nigroviridis	51.08	4.00e-84	304.00
IUUC-Ttr-128267	Tursiops truncatus	88.22	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence