iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088889

Ensembl Protein ID

ENSOGAP00000014297.2

UniProt Accession

H0XED0; H0XED0_OTOGA

Genbank Protein ID

ENSOGAP00000014297

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03171181

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015967.2	ENSOGAT00000015971.2	ENSOGAP00000014297.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.30e-08	34.5	11	54
E3 activity/RING/U-box	7.30e-07	29.2	6	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIVERY 75
           689***************************9888455444444*******************99999887 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN IVERYSAFPL DAILNARRAA RPCQAHDKVK LFCLTDRALL CFFCDEPALH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGCA GCCTCAAGGA CGAGCTGCTG TGCTCCATCT GCCTGAGCAT CTACCAAGAC 60
CCGGTGAGCC TGGGCTGCGA ACACTACTTC TGCCGCCGCT GCATCACCGA GCACTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	99.37	0.00e+00	952.00
IUUC-Apl-003767	Anas platyrhynchos	88.26	0.00e+00	801.00
IUUC-Aca-004412	Anolis carolinensis	84.10	0.00e+00	817.00
IUUC-Ame-010927	Astyanax mexicanus	82.74	0.00e+00	848.00
IUUC-Bta-012927	Bos taurus	99.16	0.00e+00	951.00
IUUC-Cja-019317	Callithrix jacchus	93.05	0.00e+00	864.00
IUUC-Cfa-020292	Canis familiaris	98.82	0.00e+00	696.00
IUUC-Cpo-022274	Cavia porcellus	98.83	0.00e+00	701.00
IUUC-Csa-023042	Chlorocebus sabaeus	99.37	0.00e+00	952.00
IUUC-Dre-028493	Danio rerio	81.68	0.00e+00	841.00
IUUC-Dno-030029	Dasypus novemcinctus	94.74	0.00e+00	892.00
IUUC-Dor-031051	Dipodomys ordii	96.92	0.00e+00	905.00
IUUC-Ete-032752	Echinops telfairi	97.80	2.00e-108	385.00
IUUC-Eca-033898	Equus caballus	78.77	0.00e+00	822.00
IUUC-Eeu-034659	Erinaceus europaeus	98.72	1.00e-83	302.00
IUUC-Fca-035492	Felis catus	90.57	0.00e+00	883.00
IUUC-Fal-036867	Ficedula albicollis	88.36	0.00e+00	854.00
IUUC-Gmo-038916	Gadus morhua	82.32	0.00e+00	818.00
IUUC-Gga-040360	Gallus gallus	90.53	0.00e+00	876.00
IUUC-Gac-041871	Gasterosteus aculeatus	82.95	0.00e+00	851.00
IUUC-Ggo-044411	Gorilla gorilla	92.45	0.00e+00	876.00
IUUC-Hsa-047025	Homo sapiens	98.74	0.00e+00	979.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	99.37	0.00e+00	952.00
IUUC-Loc-052114	Lepisosteus oculatus	84.21	0.00e+00	862.00
IUUC-Laf-054359	Loxodonta africana	93.37	0.00e+00	672.00
IUUC-Mcc-055563	Macaca mulatta	99.37	0.00e+00	952.00
IUUC-Meu-056027	Macropus eugenii	75.37	0.00e+00	722.00
IUUC-Mga-060146	Meleagris gallopavo	84.88	5.00e-75	273.00
IUUC-Mmr-060822	Microcebus murinus	99.16	0.00e+00	950.00
IUUC-Mdo-062117	Monodelphis domestica	78.47	0.00e+00	642.00
IUUC-Mmu-064086	Mus musculus	99.16	0.00e+00	951.00
IUUC-Mpu-066378	Mustela putorius furo	99.37	0.00e+00	952.00
IUUC-Mlu-067155	Myotis lucifugus	98.30	0.00e+00	963.00
IUUC-Nle-069464	Nomascus leucogenys	99.37	0.00e+00	953.00
IUUC-Opr-071058	Ochotona princeps	98.19	4.00e-133	468.00
IUUC-Ont-071253	Oreochromis niloticus	74.27	0.00e+00	728.00
IUUC-Oan-073614	Ornithorhynchus anatinus	93.04	2.00e-94	337.00
IUUC-Ola-086794	Oryzias latipes	83.16	0.00e+00	845.00
IUUC-Oar-089203	Ovis aries	95.32	0.00e+00	840.00
IUUC-Ptr-090795	Pan troglodytes	98.95	0.00e+00	980.00
IUUC-Pfo-096942	Poecilia formosa	82.53	0.00e+00	841.00
IUUC-Pab-097936	Pongo abelii	85.83	0.00e+00	631.00
IUUC-Pca-100397	Procavia capensis	97.89	0.00e+00	941.00
IUUC-Ppe-101916	Prunus persica	30.97	3.00e-10	60.80
IUUC-Pva-102293	Pteropus vampyrus	98.53	0.00e+00	684.00
IUUC-Rno-105551	Rattus norvegicus	98.95	0.00e+00	948.00
IUUC-Ssc-115983	Sus scrofa	99.37	0.00e+00	952.00
IUUC-Tgu-117279	Taeniopygia guttata	75.06	0.00e+00	654.00
IUUC-Tru-118238	Takifugu rubripes	82.74	0.00e+00	845.00
IUUC-Tni-119788	Tetraodon nigroviridis	61.09	5.00e-158	550.00
IUUC-Uma-129518	Ustilago maydis	45.83	4.00e-07	50.40
IUUC-Xtr-132768	Xenopus tropicalis	74.85	0.00e+00	729.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence