iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035826

Ensembl Protein ID

ENSFCAP00000013114.3

UniProt Accession

M3WK51; M3WK51_FELCA

Genbank Protein ID

ENSFCAP00000013114

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02178626

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000014138.3	ENSFCAT00000014143.3	ENSFCAP00000013114.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-27	94.0	153	190
UBD/Beta-Prp	6.80e-64	215.9	494	749

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsvl 98
           +++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s++
   Q: 494  RVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSIT 582
           6799*******************************************99888899***************997888999********** PP
   S: 99   slsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtlt 176
           +++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +
   Q: 583  AIKFAGNRdIQMISCGADKSIYF---RSAQQASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQ 668
           ******885789*******9976...333333334445332122222333456777788****************98888888888889 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dl 251
           g +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++
   Q: 669  G-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNC 749
           8.999999999**************************************************************554444433 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLPS VTVGVPTRRN QCSPPPAPQL CLRRRTRLSA APEDTVHNRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGGCCCGG AGGCTACGCG CGGAACGATG CAGTCGAGAA GCTGCCATCC 60
GTCACGGTGG GAGTTCCGAC GCGGAGGAAC CAGTGCTCTC CGCCTCCCGC TCCCCAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	87.77	0.00e+00	2526.00
IUUC-Atr-003165	Amborella trichopoda	34.01	3.00e-125	443.00
IUUC-Aca-004935	Anolis carolinensis	70.25	0.00e+00	989.00
IUUC-Ath-007624	Arabidopsis thaliana	30.46	1.00e-93	338.00
IUUC-Afu-008757	Aspergillus fumigatus	22.08	5.00e-30	126.00
IUUC-Ang-009797	Aspergillus niger	20.49	3.00e-20	94.00
IUUC-Ate-010425	Aspergillus terreus	23.29	5.00e-26	113.00
IUUC-Bta-013336	Bos taurus	82.50	0.00e+00	2322.00
IUUC-Cel-018592	Caenorhabditis elegans	28.61	4.00e-74	273.00
IUUC-Cja-019094	Callithrix jacchus	79.45	0.00e+00	2237.00
IUUC-Cfa-020529	Canis familiaris	88.10	0.00e+00	2557.00
IUUC-Cpo-021970	Cavia porcellus	86.16	0.00e+00	1633.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	27.70	2.00e-13	70.90
IUUC-Csa-024161	Chlorocebus sabaeus	80.03	0.00e+00	2239.00
IUUC-Cho-024310	Choloepus hoffmanni	84.68	0.00e+00	1151.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.19	8.00e-26	112.00
IUUC-Dre-028678	Danio rerio	55.96	0.00e+00	1001.00
IUUC-Dno-029933	Dasypus novemcinctus	78.03	0.00e+00	2177.00
IUUC-Dor-031147	Dipodomys ordii	78.20	0.00e+00	2144.00
IUUC-Dse-031501	Dothistroma septosporum	26.32	7.00e-25	109.00
IUUC-Eca-033675	Equus caballus	83.97	0.00e+00	2368.00
IUUC-Eeu-034798	Erinaceus europaeus	87.04	0.00e+00	870.00
IUUC-Fso-038440	Fusarium solani	22.97	1.00e-34	142.00
IUUC-Gma-043644	Glycine max	31.56	4.00e-103	369.00
IUUC-Ggo-045152	Gorilla gorilla	81.59	0.00e+00	2235.00
IUUC-Hsa-045891	Homo sapiens	81.78	0.00e+00	2258.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.81	0.00e+00	1529.00
IUUC-Lch-049669	Latimeria chalumnae	57.13	0.00e+00	1006.00
IUUC-Loc-052488	Lepisosteus oculatus	60.17	0.00e+00	1021.00
IUUC-Laf-053992	Loxodonta africana	80.05	0.00e+00	2278.00
IUUC-Mcc-054994	Macaca mulatta	81.46	0.00e+00	2229.00
IUUC-Meu-056815	Macropus eugenii	80.32	0.00e+00	1401.00
IUUC-Mtr-058383	Medicago truncatula	30.53	3.00e-50	192.00
IUUC-Mmr-060693	Microcebus murinus	79.14	0.00e+00	2214.00
IUUC-Mdo-063007	Monodelphis domestica	63.34	0.00e+00	1792.00
IUUC-Mmu-064067	Mus musculus	75.32	0.00e+00	2125.00
IUUC-Mpu-066532	Mustela putorius furo	88.95	0.00e+00	2619.00
IUUC-Mlu-066982	Myotis lucifugus	80.94	0.00e+00	2254.00
IUUC-Ncr-068758	Neurospora crassa	22.21	3.00e-30	127.00
IUUC-Nle-070042	Nomascus leucogenys	83.57	0.00e+00	1881.00
IUUC-Opr-070397	Ochotona princeps	77.88	0.00e+00	2260.00
IUUC-Oan-073119	Ornithorhynchus anatinus	67.35	0.00e+00	873.00
IUUC-Ocu-074274	Oryctolagus cuniculus	80.26	0.00e+00	2210.00
IUUC-Oga-088577	Otolemur garnettii	81.21	0.00e+00	2335.00
IUUC-Oar-090117	Ovis aries	80.45	0.00e+00	2266.00
IUUC-Ptr-090553	Pan troglodytes	81.85	0.00e+00	2283.00
IUUC-Pan-092559	Papio anubis	73.23	0.00e+00	1087.00
IUUC-Psi-093710	Pelodiscus sinensis	64.63	0.00e+00	1385.00
IUUC-Pab-098510	Pongo abelii	80.94	0.00e+00	2196.00
IUUC-Pop-099155	Populus trichocarpa	31.91	2.00e-98	354.00
IUUC-Pca-100323	Procavia capensis	71.39	0.00e+00	1326.00
IUUC-Pva-102895	Pteropus vampyrus	85.16	0.00e+00	2447.00
IUUC-Rno-105598	Rattus norvegicus	75.89	0.00e+00	2177.00
IUUC-Sha-107013	Sarcophilus harrisii	65.90	0.00e+00	1806.00
IUUC-Smo-109134	Selaginella moellendorffii	36.99	6.00e-134	472.00
IUUC-Sly-110969	Solanum lycopersicum	30.24	4.00e-94	339.00
IUUC-Sar-113261	Sorex araneus	74.81	0.00e+00	2120.00
IUUC-Ssc-115317	Sus scrofa	84.36	0.00e+00	2323.00
IUUC-Tsy-118799	Tarsius syrichta	89.28	0.00e+00	829.00
IUUC-Tni-120316	Tetraodon nigroviridis	55.96	0.00e+00	781.00
IUUC-Tre-122008	Trichoderma reesei	22.83	2.00e-31	130.00
IUUC-Tvi-122281	Trichoderma virens	24.07	2.00e-32	134.00
IUUC-Tme-127128	Tuber melanosporum	23.82	9.00e-31	129.00
IUUC-Tbe-127555	Tupaia belangeri	91.59	0.00e+00	989.00
IUUC-Ttr-128722	Tursiops truncatus	82.65	0.00e+00	2353.00
IUUC-Vda-129957	Verticillium dahliae	23.80	5.00e-32	133.00
IUUC-Vpa-130392	Vicugna pacos	69.84	3.00e-105	376.00
IUUC-Vvi-131035	Vitis vinifera	33.75	2.00e-107	384.00
IUUC-Xtr-131789	Xenopus tropicalis	59.39	0.00e+00	976.00
IUUC-Yli-134437	Yarrowia lipolytica	26.44	6.00e-17	83.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence