iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049669

Ensembl Protein ID

ENSLACP00000002382.1

UniProt Accession

H2ZYB1; H2ZYB1_LATCH

Genbank Protein ID

ENSLACP00000002382

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01252193

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002129.1	ENSLACT00000002402.1	ENSLACP00000002382.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-32	110.1	589	623
UBD/Beta-Prp	2.60e-64	217.5	364	629

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH++ vt+++f +d ++l++ s+D  i vW+l+++
   Q: 589  GHSELVTGMKFtNDcRYLITVSGDSCIFVWRLDSQ 623
           8***********999****************9876 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcv.htlk 91
           +++ks i+++k+spd+++la+g r+g ++++d++    + +++ h+aev ++++ + ++   +l+++s+Dr+i++ ++++g  + +tl 
   Q: 364  TDMKSGIRVMKISPDGQHLASGDRRGNLRIHDLHVLHEILKVEAHDAEVLCLEYFKLDPgltLLASASRDRLIHILNVDNGYSLeQTLD 452
           679999*****************************999*************97644444455*****************8766537999 PP
   S: 92   ghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee...tlsghdgvvnc.....vvvhpdgnllvsGslDrtvrlWdlktgk 170
            h++s++++++ +  +  +++s ++d+ i     +t q++ +   + s +++vv       + ++++ ++ + G+ Dr +r++++ +gk
   Q: 453  DHSSSITAVKIVAsdDEMRMISCGADKSIY---FRTAQKSVDgiqF-SRTHHVVGKttlydMDIDSTHKYAAVGCQDRNIRVYNVISGK 537
           *************644489********985...5777777777753.333333332111126789999*****************8888 PP
   S: 171  llrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgd 255
             r ++g++ ++ + l+  +d++g+ l++  +d+ + ++d+ tgecv t+ gh++ v+ ++f+++  +l+++s D  i++W  d++  d
   Q: 538  EKRCFKGAQGEDGTLLKvqMDPSGTLLATSCTDKNISIFDFYTGECVGTMFGHSELVTGMKFTNDCRYLITVSGDSCIFVWrlDSQMTD 626
           88888777777777666559999**********************************************************99988888 PP
   S: 256  llk 258
           +++
   Q: 627  CMR 629
           876 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

SGHLPAVRVW DVEEKVQLAE TQCHKYGVSC VAFSPNMRYI VSVGYQHDMI VNVWEWKKDS 60
TIASNKVSSK VTAVSFSEDS SYFVTVGNRH VKFWYLDASK ERRINATVPL IGRSGLLGEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGCTGAA GTGGTTCAAG AGGCCATTTA TTGCTATGCT TTATTTTGTA GAGCGGACAC 60
TTGCCTGCTG TTCGAGTTTG GGATGTTGAG GAAAAGGTCC AACTAGCAGA AACACAGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	58.86	0.00e+00	994.00
IUUC-Aly-006434	Arabidopsis lyrata	30.92	1.00e-56	215.00
IUUC-Bgr-012083	Blumeria graminis	22.79	9.00e-30	125.00
IUUC-Bta-013336	Bos taurus	48.99	0.00e+00	1045.00
IUUC-Cja-019094	Callithrix jacchus	58.03	0.00e+00	985.00
IUUC-Cfa-020529	Canis familiaris	59.23	0.00e+00	1006.00
IUUC-Cpo-021970	Cavia porcellus	58.14	0.00e+00	956.00
IUUC-Csa-024161	Chlorocebus sabaeus	60.71	0.00e+00	966.00
IUUC-Cho-024310	Choloepus hoffmanni	52.22	0.00e+00	707.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	25.75	3.00e-15	77.80
IUUC-Dre-028678	Danio rerio	59.07	0.00e+00	956.00
IUUC-Dor-031147	Dipodomys ordii	57.60	0.00e+00	996.00
IUUC-Eca-033675	Equus caballus	57.89	0.00e+00	981.00
IUUC-Fca-035826	Felis catus	57.81	0.00e+00	1001.00
IUUC-Ggo-045152	Gorilla gorilla	56.78	0.00e+00	984.00
IUUC-Hsa-045891	Homo sapiens	56.44	0.00e+00	974.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	64.27	0.00e+00	959.00
IUUC-Loc-052488	Lepisosteus oculatus	56.69	0.00e+00	1065.00
IUUC-Laf-053992	Loxodonta africana	59.30	0.00e+00	987.00
IUUC-Mcc-054994	Macaca mulatta	61.76	0.00e+00	984.00
IUUC-Meu-056815	Macropus eugenii	58.51	0.00e+00	952.00
IUUC-Mmr-060693	Microcebus murinus	58.42	0.00e+00	1009.00
IUUC-Mdo-063007	Monodelphis domestica	50.00	0.00e+00	1114.00
IUUC-Mmu-064067	Mus musculus	47.78	0.00e+00	1041.00
IUUC-Mpu-066532	Mustela putorius furo	59.30	0.00e+00	1008.00
IUUC-Mlu-066982	Myotis lucifugus	59.64	0.00e+00	978.00
IUUC-Nle-070042	Nomascus leucogenys	58.38	0.00e+00	978.00
IUUC-Opr-070397	Ochotona princeps	47.35	0.00e+00	1023.00
IUUC-Ocu-074274	Oryctolagus cuniculus	57.19	0.00e+00	988.00
IUUC-Oga-088577	Otolemur garnettii	58.70	0.00e+00	977.00
IUUC-Ptr-090553	Pan troglodytes	56.56	0.00e+00	979.00
IUUC-Psi-093710	Pelodiscus sinensis	56.20	0.00e+00	1107.00
IUUC-Pab-098510	Pongo abelii	60.89	0.00e+00	991.00
IUUC-Pca-100323	Procavia capensis	58.07	0.00e+00	785.00
IUUC-Pva-102895	Pteropus vampyrus	54.19	0.00e+00	1058.00
IUUC-Rno-105598	Rattus norvegicus	59.85	0.00e+00	997.00
IUUC-Sha-107013	Sarcophilus harrisii	59.65	0.00e+00	1031.00
IUUC-Sar-113261	Sorex araneus	61.01	0.00e+00	986.00
IUUC-Ssc-115317	Sus scrofa	60.34	0.00e+00	996.00
IUUC-Tsy-118799	Tarsius syrichta	64.54	4.00e-157	549.00
IUUC-Ttr-128722	Tursiops truncatus	47.35	0.00e+00	992.00
IUUC-Vda-129957	Verticillium dahliae	27.94	1.00e-19	92.40
IUUC-Vpa-130392	Vicugna pacos	66.88	9.00e-64	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence