iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067860

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02043780

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002253.2	ENSMLUT00000002252.2	ENSMLUP00000002049.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.90e-31	107.1	2	95

Active Site

Position(s)	Description	Evidence
35	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 49   leiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspalsvesvllsiqsllaepnpesplneeaaell 126
           ++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+           ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ ++
   Q: 2    ARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMY 90
           689***********************************999999999*9**************************************** PP
   S: 127  kknre 131
           +k++e
   Q: 91   RKWKE 95
           **998 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

QARLKFPIDY PYSPPAFRFL TKMWHPNIYE TGDVCISILH PPVDDPQSGE LPSERWNPTQ 60
NVRTILLSVI SLLNEPNTFS PANVDASVMY RKWKESKGKD REYTDIIRKQ VLGTKVDAER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCACGCC TCAAGTTTCC CATCGACTAC CCTTACTCCC CACCAGCCTT TCGGTTCCTG 60
ACCAAGATGT GGCACCCCAA CATCTATGAG GTGAGCCTGC CTCTCCCCAC TTACCCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Fca-035832	Felis catus	98.19	1.00e-93	335.00
IUUC-Fal-036936	Ficedula albicollis	98.62	3.00e-83	300.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	98.65	5.00e-85	306.00
IUUC-Meu-056360	Macropus eugenii	92.09	1.00e-86	311.00
IUUC-Oar-090180	Ovis aries	98.78	3.00e-86	310.00
IUUC-Psi-093039	Pelodiscus sinensis	90.45	3.00e-88	317.00
IUUC-Pca-100169	Procavia capensis	86.43	6.00e-66	243.00
IUUC-Pva-102875	Pteropus vampyrus	100.00	5.00e-85	306.00
IUUC-Sha-106475	Sarcophilus harrisii	99.32	6.00e-85	306.00
IUUC-Ssc-115699	Sus scrofa	92.00	6.00e-86	309.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence