iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001745

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01177221

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000002251.1	ENSAMET00000002484.1	ENSAMEP00000002383.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.53	0.00e+00	889.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.60	5.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

TCVSLVAPPQ NMVMSFRVSD LQMLLGFVGR SKSGLKHELV TRALQLVQFD CSPELFKKIK 60
ELYETRYAKK SSEPVPQAHR PLDPLTMHST YDRAGTVPRT PLSGPNIDYP VLYGKYLNGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATGTGTAT CTCTTGTTGC TCCTCCCCAG AACATGGTGA TGAGTTTCCG AGTCTCCGAT 60
CTTCAGATGC TTCTGGGTTT TGTTGGCCGG AGTAAGAGTG GGCTTAAACA CGAACTTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003765	Anas platyrhynchos	80.86	0.00e+00	811.00
IUUC-Ame-010763	Astyanax mexicanus	58.18	4.00e-140	491.00
IUUC-Bta-012369	Bos taurus	95.09	0.00e+00	892.00
IUUC-Cja-019450	Callithrix jacchus	91.55	0.00e+00	877.00
IUUC-Cfa-020933	Canis familiaris	94.31	0.00e+00	891.00
IUUC-Cpo-022112	Cavia porcellus	92.11	0.00e+00	837.00
IUUC-Csa-023913	Chlorocebus sabaeus	79.30	0.00e+00	705.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.12	5.00e-32	132.00
IUUC-Dre-027609	Danio rerio	58.80	5.00e-136	477.00
IUUC-Dno-029664	Dasypus novemcinctus	74.70	2.00e-150	526.00
IUUC-Ete-032988	Echinops telfairi	90.94	2.00e-165	575.00
IUUC-Eca-034430	Equus caballus	90.31	0.00e+00	877.00
IUUC-Fca-035968	Felis catus	98.63	4.00e-171	593.00
IUUC-Fal-037449	Ficedula albicollis	81.60	0.00e+00	795.00
IUUC-Fso-038103	Fusarium solani	36.07	1.00e-26	114.00
IUUC-Gmo-038925	Gadus morhua	60.70	1.00e-133	469.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.49	2.00e-29	123.00
IUUC-Gga-040362	Gallus gallus	83.33	0.00e+00	825.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.03	1.00e-127	449.00
IUUC-Ggo-044810	Gorilla gorilla	90.57	0.00e+00	838.00
IUUC-Hsa-045784	Homo sapiens	92.53	0.00e+00	887.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	90.66	0.00e+00	865.00
IUUC-Lch-049727	Latimeria chalumnae	69.95	2.00e-150	524.00
IUUC-Loc-052354	Lepisosteus oculatus	52.19	8.00e-115	407.00
IUUC-Laf-054261	Loxodonta africana	91.96	0.00e+00	885.00
IUUC-Mcc-054931	Macaca mulatta	91.75	0.00e+00	871.00
IUUC-Meu-056468	Macropus eugenii	85.69	0.00e+00	847.00
IUUC-Mpo-057405	Magnaporthe poae	33.61	6.00e-29	122.00
IUUC-Mga-059981	Meleagris gallopavo	86.79	0.00e+00	691.00
IUUC-Mvi-060421	Microbotryum violaceum	28.61	1.00e-25	111.00
IUUC-Mmr-061181	Microcebus murinus	90.55	0.00e+00	844.00
IUUC-Mdo-062345	Monodelphis domestica	85.29	0.00e+00	845.00
IUUC-Mmu-063197	Mus musculus	85.69	0.00e+00	816.00
IUUC-Mpu-066275	Mustela putorius furo	95.87	0.00e+00	903.00
IUUC-Mlu-067194	Myotis lucifugus	93.74	0.00e+00	889.00
IUUC-Ncr-068929	Neurospora crassa	28.09	4.00e-27	115.00
IUUC-Ont-072227	Oreochromis niloticus	58.56	4.00e-133	468.00
IUUC-Ola-086865	Oryzias latipes	59.02	2.00e-131	462.00
IUUC-Oga-088945	Otolemur garnettii	92.14	0.00e+00	885.00
IUUC-Oar-089412	Ovis aries	92.16	0.00e+00	877.00
IUUC-Ptr-091550	Pan troglodytes	83.38	0.00e+00	627.00
IUUC-Pan-092183	Papio anubis	91.55	0.00e+00	884.00
IUUC-Psi-093003	Pelodiscus sinensis	82.94	0.00e+00	821.00
IUUC-Pfo-096704	Poecilia formosa	58.76	3.00e-135	475.00
IUUC-Pab-097923	Pongo abelii	95.48	0.00e+00	739.00
IUUC-Pca-100249	Procavia capensis	76.78	3.00e-141	494.00
IUUC-Pva-102562	Pteropus vampyrus	88.78	0.00e+00	836.00
IUUC-Rno-105762	Rattus norvegicus	86.08	0.00e+00	818.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.09	8.00e-28	118.00
IUUC-Sha-107253	Sarcophilus harrisii	85.49	0.00e+00	846.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.65	2.00e-28	121.00
IUUC-Sar-113149	Sorex araneus	84.62	2.00e-122	432.00
IUUC-Ssc-115241	Sus scrofa	95.28	0.00e+00	899.00
IUUC-Tgu-116884	Taeniopygia guttata	81.80	0.00e+00	789.00
IUUC-Tru-118031	Takifugu rubripes	59.03	4.00e-139	488.00
IUUC-Tni-119766	Tetraodon nigroviridis	59.03	3.00e-134	471.00
IUUC-Ttr-128556	Tursiops truncatus	83.70	0.00e+00	733.00
IUUC-Xtr-131866	Xenopus tropicalis	75.44	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence