iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107926

Ensembl Protein ID

EEB08780

UniProt Accession

B6K5H6; B6K5H6_SCHJY

Genbank Protein ID

EEB08780.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

KE651167

Gene Name

SJAG_03950

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_03950	EEB08780	EEB08780

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.80e-71	239.5	8	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitele 101
           YDRQ+rlw + +q k+++a+ +l+ +  +GcE lKnL+l G+g+i+++D++ v++s    +F++++ed  ksK+e+ ae l +lnpdv +e+ + ++ ++ 
   Q: 8    YDRQLRLWEAAGQSKIENASCCLLYVNNVGCECLKNLILPGIGKICILDDRLVDKSVDAPNFFLDEEDHNKSKVECLAENLSRLNPDVCIESKKANPLDII 108
           ****************************************************************************************************9 PP
   S: 102  eeiv.FfkkfdvVvlaldnrearr.kvnrlclnarvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpn......aaehtiewa.. 190
            ++  Ff  f+vV+la++  + ++ k+ + ++n ++ ++  ++ G+ G +rv+++  t+ + ++d   ++++++P+ +lke+         ++++   +  
   Q: 109  SSDIdFFHSFNVVILADMLPKIQLiKLTNYLWNKQIAFLQLRSIGFNGSIRVCLPDCTILQTQNDasLDLRLNMPWAELKEYSKqlfereSKDRHGDIPfv 209
           99999***********9877766449***************************************999**************6666666666666665533 PP
   S: 191  vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv................ 274
           +++ +  ++ +  +++++ ++++++++ + k+  ++  +deenfeea ++  + f++t+i+s  k+++++++c+++++++s+fw+                
   Q: 210  AILVHGCSQLETGNKGNPSSQRKDILRNWIKT--QMLYADEENFEEALSNCWRPFQSTNISSaLKTIFDDINCQNLNEQSSSFWIimnaickfvecyhcip 308
           66666666666666666666666666666665..9999*************************************************************** PP
   S: 275  .........................................................sfcsnaealq..........vpekvekdeevvkasap....lyl 304
                                                                    +fc+na++++              +    + ++++++    +y+
   Q: 309  vsgilpdmkagssefvslqrvyqqkakedalkvknyvqknlkllsrpidsitddeifQFCKNASQARyikyrkieeeL---NSPLLTDLASDNEslvpWYF 406
           *******************************************************************87777753322...33333333333336779*** PP
   S: 305  llralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep.kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           ++r  +  +++++++p + s+  +        +++a+  ++slg +p +   ++ +ei++++ ++i++++a++g++aaqE+iK ++ ++ pl+n+ l+da
   Q: 407  AFRCFDIYKERYNSSP-DASLTSSIH----KYEEIACEFMKSLGQSPtQSVCNACREISRSAGAEIHSVSAFIGAIAAQEAIKFLTRQYIPLNNTCLVDA 501
           ****************.333333333....3455555556899999989999********************************************9987 PP

Organism

Schizosaccharomyces japonicus

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MSFHQNKYDR QLRLWEAAGQ SKIENASCCL LYVNNVGCEC LKNLILPGIG KICILDDRLV 60
DKSVDAPNFF LDEEDHNKSK VECLAENLSR LNPDVCIESK KANPLDIISS DIDFFHSFNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGTATGA AAATGCCTTT CCAGGCCAAC TTCATACACC GATTTTTTGA ACCGACTTCA 60
GGACATTAAA ATATATCAAT TCCGTGTGAT TTTTTTGCAA AAATGAGTTT TCATCAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	33.40	8.00e-76	275.00
IUUC-Aml-002333	Ailuropoda melanoleuca	33.21	1.00e-78	285.00
IUUC-Atr-002644	Amborella trichopoda	31.86	4.00e-72	263.00
IUUC-Apl-003446	Anas platyrhynchos	32.57	7.00e-67	246.00
IUUC-Aca-004450	Anolis carolinensis	31.83	6.00e-76	276.00
IUUC-Aly-005466	Arabidopsis lyrata	32.17	3.00e-76	277.00
IUUC-Ath-007600	Arabidopsis thaliana	33.33	7.00e-79	285.00
IUUC-Ago-007900	Ashbya gossypii	23.70	8.00e-29	119.00
IUUC-Acl-008333	Aspergillus clavatus	31.49	4.00e-73	266.00
IUUC-Afl-008529	Aspergillus flavus	30.97	1.00e-70	258.00
IUUC-Afu-009071	Aspergillus fumigatus	31.68	5.00e-70	256.00
IUUC-Ani-009443	Aspergillus nidulans	31.57	2.00e-66	244.00
IUUC-Ang-009669	Aspergillus niger	30.52	9.00e-69	252.00
IUUC-Aor-009914	Aspergillus oryzae	30.87	3.00e-69	253.00
IUUC-Ate-010450	Aspergillus terreus	31.08	2.00e-70	258.00
IUUC-Ame-011183	Astyanax mexicanus	32.34	2.00e-75	274.00
IUUC-Bgr-012111	Blumeria graminis	31.77	2.00e-61	228.00
IUUC-Bta-012583	Bos taurus	32.58	2.00e-77	281.00
IUUC-Bci-013892	Botrytis cinerea	32.18	2.00e-62	231.00
IUUC-Bdi-014592	Brachypodium distachyon	33.33	2.00e-77	280.00
IUUC-Bol-016399	Brassica oleracea	32.05	1.00e-76	278.00
IUUC-Bra-017506	Brassica rapa	30.84	7.00e-75	272.00
IUUC-Cel-018456	Caenorhabditis elegans	28.75	1.00e-57	215.00
IUUC-Cja-020007	Callithrix jacchus	32.52	3.00e-77	280.00
IUUC-Cfa-020324	Canis familiaris	33.46	9.00e-80	288.00
IUUC-Cpo-022248	Cavia porcellus	32.29	2.00e-43	167.00
IUUC-Csa-023149	Chlorocebus sabaeus	31.58	4.00e-60	223.00
IUUC-Cho-024537	Choloepus hoffmanni	27.86	3.00e-47	180.00
IUUC-Cin-025763	Ciona intestinalis	30.94	2.00e-67	248.00
IUUC-Csv-026113	Ciona savignyi	31.21	5.00e-66	243.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	31.65	5.00e-62	229.00
IUUC-Cne-026884	Cryptococcus neoformans	27.32	3.00e-54	204.00
IUUC-Dre-028140	Danio rerio	33.90	2.00e-75	274.00
IUUC-Dno-030033	Dasypus novemcinctus	34.12	1.00e-67	248.00
IUUC-Dor-030513	Dipodomys ordii	42.55	2.00e-15	74.70
IUUC-Dse-031536	Dothistroma septosporum	29.50	9.00e-66	242.00
IUUC-Dme-031683	Drosophila melanogaster	34.42	1.00e-71	261.00
IUUC-Ete-032420	Echinops telfairi	28.32	1.00e-55	208.00
IUUC-Eca-033992	Equus caballus	31.32	1.00e-58	218.00
IUUC-Eeu-034713	Erinaceus europaeus	24.51	9.00e-18	82.80
IUUC-Fca-036548	Felis catus	33.14	9.00e-78	282.00
IUUC-Fal-037600	Ficedula albicollis	32.31	1.00e-65	241.00
IUUC-Fox-038037	Fusarium oxysporum	31.58	1.00e-65	241.00
IUUC-Fso-038387	Fusarium solani	32.59	6.00e-67	246.00
IUUC-Gmo-038562	Gadus morhua	31.21	2.00e-71	261.00
IUUC-Ggr-040005	Gaeumannomyces graminis	30.78	7.00e-63	232.00
IUUC-Gga-041129	Gallus gallus	33.33	3.00e-70	257.00
IUUC-Gac-042558	Gasterosteus aculeatus	33.46	1.00e-73	268.00
IUUC-Gma-043610	Glycine max	31.62	1.00e-74	271.00
IUUC-Ggo-045611	Gorilla gorilla	32.96	3.00e-77	280.00
IUUC-Hsa-046563	Homo sapiens	33.14	3.00e-78	283.00
IUUC-Hvu-047790	Hordeum vulgare	31.85	9.00e-51	192.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	32.77	1.00e-77	281.00
IUUC-Kpa-049309	Komagataella pastoris	31.41	7.00e-66	242.00
IUUC-Lch-050038	Latimeria chalumnae	32.07	7.00e-72	262.00
IUUC-Lpe-051535	Leersia perrieri	33.33	2.00e-67	248.00
IUUC-Loc-051917	Lepisosteus oculatus	31.73	5.00e-66	243.00
IUUC-Lma-053112	Leptosphaeria maculans	30.31	4.00e-67	247.00
IUUC-Laf-053690	Loxodonta africana	32.77	4.00e-78	283.00
IUUC-Mcc-055117	Macaca mulatta	33.40	2.00e-76	278.00
IUUC-Meu-056761	Macropus eugenii	27.92	2.00e-56	211.00
IUUC-Mor-057230	Magnaporthe oryzae	31.84	4.00e-68	249.00
IUUC-Mpo-057514	Magnaporthe poae	31.90	2.00e-59	221.00
IUUC-Mtr-058551	Medicago truncatula	30.67	2.00e-68	251.00
IUUC-Mla-059183	Melampsora laricipopulina	30.97	2.00e-77	281.00
IUUC-Mga-060144	Meleagris gallopavo	32.64	2.00e-67	248.00
IUUC-Mvi-060221	Microbotryum violaceum	28.76	1.00e-59	222.00
IUUC-Mmr-061325	Microcebus murinus	32.65	6.00e-74	269.00
IUUC-Mdo-062532	Monodelphis domestica	33.14	3.00e-78	283.00
IUUC-Mmu-063956	Mus musculus	32.77	1.00e-78	285.00
IUUC-Mac-064521	Musa acuminata	35.14	3.00e-78	283.00
IUUC-Mpu-066716	Mustela putorius furo	32.86	1.00e-71	261.00
IUUC-Mlu-067459	Myotis lucifugus	33.02	2.00e-80	291.00
IUUC-Nfi-068245	Neosartorya fischeri	31.68	5.00e-68	249.00
IUUC-Ncr-068910	Neurospora crassa	32.17	8.00e-68	249.00
IUUC-Nle-070034	Nomascus leucogenys	31.77	1.00e-71	261.00
IUUC-Opr-070552	Ochotona princeps	29.96	3.00e-54	204.00
IUUC-Ont-071426	Oreochromis niloticus	34.17	3.00e-80	290.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.54	1.00e-51	195.00
IUUC-Ocu-074911	Oryctolagus cuniculus	32.51	4.00e-77	280.00
IUUC-Oba-075437	Oryza barthii	32.95	9.00e-70	255.00
IUUC-Obr-076684	Oryza brachyantha	32.50	2.00e-60	224.00
IUUC-Ogl-077170	Oryza glaberrima	32.95	9.00e-70	255.00
IUUC-Ogu-078844	Oryza glumaepatula	33.60	7.00e-66	242.00
IUUC-Oin-079105	Oryza indica	32.95	1.00e-69	255.00
IUUC-Olo-080943	Oryza longistaminata	31.87	4.00e-61	226.00
IUUC-Oni-082891	Oryza nivara	31.23	4.00e-65	239.00
IUUC-Opu-083457	Oryza punctata	32.76	1.00e-68	251.00
IUUC-Oru-084960	Oryza rufipogon	31.87	4.00e-61	226.00
IUUC-Osa-085358	Oryza sativa	32.95	1.00e-69	255.00
IUUC-Ola-086420	Oryzias latipes	31.12	8.00e-45	172.00
IUUC-Olu-087625	Ostreococcus lucimarinus	26.87	1.00e-43	169.00
IUUC-Oga-088810	Otolemur garnettii	33.27	2.00e-79	287.00
IUUC-Oar-089196	Ovis aries	32.39	9.00e-76	275.00
IUUC-Ptr-090617	Pan troglodytes	32.95	4.00e-78	283.00
IUUC-Pan-092761	Papio anubis	33.33	1.00e-79	288.00
IUUC-Psi-093191	Pelodiscus sinensis	32.38	6.00e-69	253.00
IUUC-Pma-094380	Petromyzon marinus	31.64	8.00e-63	232.00
IUUC-Pno-095084	Phaeosphaeria nodorum	28.57	1.00e-53	203.00
IUUC-Ppa-095798	Physcomitrella patens	28.84	3.00e-64	237.00
IUUC-Pfo-096467	Poecilia formosa	32.20	2.00e-75	274.00
IUUC-Pab-098255	Pongo abelii	34.40	6.00e-68	249.00
IUUC-Pop-099871	Populus trichocarpa	32.25	8.00e-76	275.00
IUUC-Pca-100807	Procavia capensis	35.52	3.00e-27	114.00
IUUC-Ppe-101280	Prunus persica	32.76	1.00e-78	285.00
IUUC-Pva-102333	Pteropus vampyrus	31.20	2.00e-67	248.00
IUUC-Pgr-103401	Puccinia graminis	27.74	2.00e-59	221.00
IUUC-Ptt-103889	Puccinia triticina	23.91	3.00e-44	171.00
IUUC-Pte-104355	Pyrenophora teres	29.48	2.00e-62	231.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	29.66	5.00e-62	229.00
IUUC-Rno-105810	Rattus norvegicus	32.95	4.00e-77	280.00
IUUC-Sce-106397	Saccharomyces cerevisiae	22.75	2.00e-18	84.70
IUUC-Sha-106770	Sarcophilus harrisii	35.04	8.00e-39	151.00
IUUC-Spo-108276	Schizosaccharomyces pombe	37.38	2.00e-101	360.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	31.20	4.00e-59	220.00
IUUC-Smo-109213	Selaginella moellendorffii	32.25	4.00e-71	259.00
IUUC-Sit-110157	Setaria italica	34.94	6.00e-84	302.00
IUUC-Sly-111105	Solanum lycopersicum	31.95	7.00e-75	272.00
IUUC-Stu-112469	Solanum tuberosum	31.95	8.00e-75	272.00
IUUC-Sar-113083	Sorex araneus	28.40	1.00e-25	109.00
IUUC-Sbi-113813	Sorghum bicolor	33.40	8.00e-81	292.00
IUUC-Sre-115058	Sporisorium reilianum	33.17	1.00e-58	219.00
IUUC-Tgu-116772	Taeniopygia guttata	31.95	1.00e-65	241.00
IUUC-Tru-118686	Takifugu rubripes	32.08	8.00e-76	275.00
IUUC-Tsy-119111	Tarsius syrichta	32.85	1.00e-32	132.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.21	1.00e-59	222.00
IUUC-Tca-121491	Theobroma cacao	31.81	1.00e-70	258.00
IUUC-Tre-122103	Trichoderma reesei	32.22	3.00e-64	237.00
IUUC-Tvi-122672	Trichoderma virens	33.71	1.00e-65	241.00
IUUC-Tae-125316	Triticum aestivum	33.33	3.00e-77	280.00
IUUC-Tur-126487	Triticum urartu	32.50	3.00e-71	260.00
IUUC-Tme-127097	Tuber melanosporum	32.97	1.00e-75	275.00
IUUC-Ttr-128465	Tursiops truncatus	30.90	4.00e-68	249.00
IUUC-Uma-129645	Ustilago maydis	28.23	6.00e-61	226.00
IUUC-Vda-129989	Verticillium dahliae	29.26	9.00e-55	205.00
IUUC-Vpa-130529	Vicugna pacos	31.27	3.00e-71	260.00
IUUC-Vvi-131059	Vitis vinifera	32.57	5.00e-76	276.00
IUUC-Xtr-132002	Xenopus tropicalis	34.72	5.00e-80	289.00
IUUC-Xma-133930	Xiphophorus maculatus	32.65	2.00e-74	270.00
IUUC-Yli-134505	Yarrowia lipolytica	28.80	5.00e-70	256.00
IUUC-Zma-135619	Zea mays	33.20	1.00e-71	261.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence