iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015703.3	ENSFCAT00000026591.1	ENSFCAP00000017684.1
ENSFCAG00000015703.3	ENSFCAT00000015707.3	ENSFCAP00000014563.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-18	64.9	204	237

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 204  HEQEVNCVDCRGGIIVSGSRDRTAKVWPLASGRL 237
           99*******9669***************999875 PP

Organism

Felis catus

Protein Sequence
(Fasta)

AGAAGEAMAA ATEEEAAARE PAGRPAAGPA LLRLPEELLL LICSYLDMRA LGRLAQVCRW 60
LRRFFSFFFK WSKFSRSSLN LGYPSVEREK MANVPVKERV KVSQNWRLGR CREGILLKWR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGGGCGG CGGGGGAGGC CATGGCGGCG GCGACCGAGG AGGAGGCGGC GGCCCGGGAG 60
CCGGCCGGCC GCCCCGCTGC GGGGCCCGCG CTCTTGCGCC TGCCGGAGGA GCTGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	94.12	0.00e+00	721.00
IUUC-Apl-003837	Anas platyrhynchos	71.91	3.00e-143	500.00
IUUC-Aca-004776	Anolis carolinensis	65.23	3.00e-132	464.00
IUUC-Ame-010651	Astyanax mexicanus	61.04	5.00e-113	400.00
IUUC-Bta-013495	Bos taurus	91.98	0.00e+00	677.00
IUUC-Cja-018901	Callithrix jacchus	92.41	0.00e+00	671.00
IUUC-Cfa-021251	Canis familiaris	93.58	0.00e+00	718.00
IUUC-Cpo-021750	Cavia porcellus	93.85	0.00e+00	644.00
IUUC-Csa-024026	Chlorocebus sabaeus	92.14	0.00e+00	700.00
IUUC-Cho-024496	Choloepus hoffmanni	71.27	2.00e-145	508.00
IUUC-Cin-025142	Ciona intestinalis	29.75	3.00e-18	85.10
IUUC-Csv-025883	Ciona savignyi	37.83	2.00e-62	232.00
IUUC-Dre-027447	Danio rerio	56.57	4.00e-118	417.00
IUUC-Dno-029572	Dasypus novemcinctus	81.08	4.00e-169	587.00
IUUC-Dor-030982	Dipodomys ordii	83.74	7.00e-180	622.00
IUUC-Dme-031804	Drosophila melanogaster	22.35	3.00e-13	69.70
IUUC-Ete-032917	Echinops telfairi	95.69	0.00e+00	656.00
IUUC-Eca-033969	Equus caballus	92.35	0.00e+00	677.00
IUUC-Eeu-034850	Erinaceus europaeus	81.57	2.00e-175	608.00
IUUC-Fal-037391	Ficedula albicollis	66.93	3.00e-145	508.00
IUUC-Gmo-038632	Gadus morhua	56.30	1.00e-118	419.00
IUUC-Gga-040783	Gallus gallus	69.27	2.00e-152	531.00
IUUC-Gac-042314	Gasterosteus aculeatus	54.52	4.00e-99	354.00
IUUC-Ggo-044739	Gorilla gorilla	92.14	0.00e+00	699.00
IUUC-Hsa-046705	Homo sapiens	92.14	0.00e+00	670.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	98.27	5.00e-172	596.00
IUUC-Loc-052397	Lepisosteus oculatus	64.17	2.00e-129	455.00
IUUC-Laf-054544	Loxodonta africana	94.94	0.00e+00	663.00
IUUC-Meu-056363	Macropus eugenii	58.15	8.00e-102	363.00
IUUC-Mga-059275	Meleagris gallopavo	73.35	2.00e-144	504.00
IUUC-Mmr-060906	Microcebus murinus	92.14	0.00e+00	698.00
IUUC-Mdo-062400	Monodelphis domestica	72.99	4.00e-163	567.00
IUUC-Mmu-063556	Mus musculus	88.66	0.00e+00	674.00
IUUC-Mpu-066500	Mustela putorius furo	94.39	0.00e+00	724.00
IUUC-Mlu-068074	Myotis lucifugus	98.46	0.00e+00	671.00
IUUC-Nle-069601	Nomascus leucogenys	92.41	0.00e+00	701.00
IUUC-Opr-070904	Ochotona princeps	81.49	9.00e-133	466.00
IUUC-Ont-072679	Oreochromis niloticus	54.60	5.00e-112	397.00
IUUC-Oan-073434	Ornithorhynchus anatinus	66.82	3.00e-73	267.00
IUUC-Ocu-074649	Oryctolagus cuniculus	90.51	0.00e+00	682.00
IUUC-Ola-087336	Oryzias latipes	48.26	3.00e-93	335.00
IUUC-Oga-088590	Otolemur garnettii	89.95	0.00e+00	656.00
IUUC-Oar-090178	Ovis aries	90.93	0.00e+00	657.00
IUUC-Pan-092881	Papio anubis	92.41	0.00e+00	700.00
IUUC-Pfo-096176	Poecilia formosa	54.67	1.00e-102	366.00
IUUC-Pab-098285	Pongo abelii	92.41	0.00e+00	701.00
IUUC-Pca-100888	Procavia capensis	86.63	0.00e+00	649.00
IUUC-Pva-102184	Pteropus vampyrus	79.13	9.00e-166	576.00
IUUC-Rno-105668	Rattus norvegicus	88.66	0.00e+00	674.00
IUUC-Sha-106629	Sarcophilus harrisii	77.64	5.00e-155	540.00
IUUC-Ssc-116183	Sus scrofa	93.58	0.00e+00	719.00
IUUC-Tgu-116630	Taeniopygia guttata	68.19	3.00e-152	531.00
IUUC-Tru-118761	Takifugu rubripes	51.48	9.00e-109	386.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	6.00e-60	223.00
IUUC-Ttr-128582	Tursiops truncatus	91.18	0.00e+00	669.00
IUUC-Vpa-130431	Vicugna pacos	76.19	4.00e-98	350.00
IUUC-Xtr-132655	Xenopus tropicalis	63.96	5.00e-138	484.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence