iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071562

Ensembl Protein ID

ENSONIP00000004023.1

UniProt Accession

I3J583; I3J583_ORENI

Genbank Protein ID

ENSONIP00000004023

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01013896

Gene Name

cul4a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000003207.1	ENSONIT00000004024.1	ENSONIP00000004023.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.80e-212	707.8	62	657

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkif 87
           klr+av +i++++s+k+++eely+av+nlc++kv+  lYk+l++v+e+++ +q+++ +ees d+  +Lk +nr+W+++++q  ++r+if
   Q: 62   KLRDAVGAIQNSTSIKYNLEELYQAVENLCSYKVSPTLYKQLRQVCEDHVqAQIHQFREESLDNLsFLKRMNRCWQDHCRQTIMIRSIF 150
           5899**********************************************99************99*********************** PP
   S: 88   ayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfle 174
           ++ldrtyv +++ + ++++ +l+l+r++iv+d  ++kr++e +l+ ie eR+ge+vdr+ll+++  +l++L     ++yk+sFE++fl+
   Q: 151  LFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDsaVQKRTVEGILEQIELERNGETVDRSLLRSLLGMLSDL-----QVYKDSFEERFLT 234
           **********9999*****************************************************9998.....9************ PP
   S: 175  atqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLl 262
           +t+++y+ae ++++qe++v eYl++v  rl+ee++r+  yl++st+++L+++vek+l+ +h++++l ++l  ll++++  +l+++y+L+
   Q: 235  ETNRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRIVSYLDQSTQKPLISCVEKQLLGEHMTAILqKGLSTLLDENRVTELTLLYQLF 323
           ****************************************************************9989********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.E 350
           s+v+ gl +ll+ ++ +ik+ g +++  +ek+kd   +V++ll++k+k++++ +++F  ++ F++a+++afetf+nk+     +++p E
   Q: 324  SKVKGGLPTLLQFWRDYIKSFGGEIVCTPEKDKD---MVQDLLDFKDKMDNVAQSCFARNESFINAMKEAFETFINKR-----PNKPaE 404
           **********************************...*****************************************.....66666* PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           l+A+y+D++Lr+++k++teeele++ldk++++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+
   Q: 405  LIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFK 493
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkk 528
           d+++S+d+++qFk+  +n++e  ++el+v++L++g+Wp ++ +e v+LP+e+ k++e f+ fYl khsgRkLqWq tlg+a lkae+k+
   Q: 494  DMELSKDIMIQFKQYIQNQSEPSNIELTVNILTMGYWPSYTPME-VHLPTEMVKLQEVFKLFYLGKHSGRKLQWQPTLGHAVLKAEFKE 581
           ****************************************9999.******************************************** PP
   S: 529  gkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           gk+elqVs fQ++vLL+fn+ e++s+ee+++at+++e eL+rtlqsL+++k++vl+k+p +k++e++d f +N++f
   Q: 582  GKKELQVSLFQTLVLLMFNEGEEFSMEEIRAATGIEEGELKRTLQSLACGKARVLNKNPRGKDVEDGDRFNFNNDF 657
           **************************************************************************98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAEDTRQDKR ASFSITEHSA NGMARTSAVA SGKTGTSKKL VIKNFKDRPK LAENYTEDTW 60
LKLRDAVGAI QNSTSIKYNL EELYQAVENL CSYKVSPTLY KQLRQVCEDH VQAQIHQFRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTTCCTC CGTAGAGTTC TTATTATGAC TAAAGCTTCT TAATTTAATG ACTAATGCAA 60
AAAAAAAGTT GCTGTCCTTT TGATGGCAAA CTGATTTATT GTTACTGATA TTTAAGTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0035118--P:embryonic pectoral fin morphogenesis
GO:0007507--P:heart development
GO:0071600--P:otic vesicle morphogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000285	Aegilops tauschii	55.07	0.00e+00	817.00
IUUC-Aml-002062	Ailuropoda melanoleuca	81.70	0.00e+00	1257.00
IUUC-Atr-002727	Amborella trichopoda	56.80	0.00e+00	799.00
IUUC-Apl-004157	Anas platyrhynchos	81.88	0.00e+00	1258.00
IUUC-Aca-004430	Anolis carolinensis	81.26	0.00e+00	1248.00
IUUC-Aly-006547	Arabidopsis lyrata	56.02	0.00e+00	804.00
IUUC-Ath-006748	Arabidopsis thaliana	56.00	0.00e+00	801.00
IUUC-Acl-008359	Aspergillus clavatus	36.01	1.00e-123	437.00
IUUC-Afl-008567	Aspergillus flavus	38.76	3.00e-135	476.00
IUUC-Afu-008833	Aspergillus fumigatus	37.32	3.00e-134	473.00
IUUC-Ani-009373	Aspergillus nidulans	37.55	2.00e-136	480.00
IUUC-Ang-009622	Aspergillus niger	38.35	2.00e-133	469.00
IUUC-Aor-010241	Aspergillus oryzae	38.71	3.00e-133	469.00
IUUC-Ate-010251	Aspergillus terreus	39.22	3.00e-139	489.00
IUUC-Ame-010809	Astyanax mexicanus	92.24	0.00e+00	1407.00
IUUC-Bgr-012219	Blumeria graminis	35.45	4.00e-112	399.00
IUUC-Bta-013244	Bos taurus	81.83	0.00e+00	1256.00
IUUC-Bci-013744	Botrytis cinerea	38.22	3.00e-125	442.00
IUUC-Bdi-014223	Brachypodium distachyon	54.33	0.00e+00	815.00
IUUC-Bol-016036	Brassica oleracea	56.33	0.00e+00	828.00
IUUC-Bra-017794	Brassica rapa	56.56	0.00e+00	828.00
IUUC-Cja-019180	Callithrix jacchus	81.83	0.00e+00	1261.00
IUUC-Cfa-021189	Canis familiaris	81.83	0.00e+00	1261.00
IUUC-Cpo-021928	Cavia porcellus	81.94	0.00e+00	1261.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	47.97	6.00e-179	621.00
IUUC-Csa-023831	Chlorocebus sabaeus	81.83	0.00e+00	1261.00
IUUC-Cho-024899	Choloepus hoffmanni	85.52	0.00e+00	907.00
IUUC-Cin-025727	Ciona intestinalis	61.73	0.00e+00	760.00
IUUC-Csv-026117	Ciona savignyi	52.95	0.00e+00	860.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	37.84	7.00e-123	435.00
IUUC-Cme-027355	Cyanidioschyzon merolae	32.98	4.00e-110	392.00
IUUC-Dre-027916	Danio rerio	79.60	0.00e+00	1211.00
IUUC-Dno-028879	Dasypus novemcinctus	75.42	0.00e+00	1172.00
IUUC-Dor-030698	Dipodomys ordii	82.78	0.00e+00	1204.00
IUUC-Dse-031159	Dothistroma septosporum	36.23	3.00e-125	442.00
IUUC-Dme-031652	Drosophila melanogaster	64.64	0.00e+00	944.00
IUUC-Ete-033101	Echinops telfairi	78.51	0.00e+00	1115.00
IUUC-Eca-033952	Equus caballus	81.23	0.00e+00	1249.00
IUUC-Eeu-034767	Erinaceus europaeus	77.02	0.00e+00	1159.00
IUUC-Fca-036211	Felis catus	80.81	0.00e+00	1235.00
IUUC-Fal-037248	Ficedula albicollis	81.99	0.00e+00	1263.00
IUUC-Fox-037854	Fusarium oxysporum	37.68	2.00e-121	430.00
IUUC-Fso-038138	Fusarium solani	38.03	1.00e-128	454.00
IUUC-Gmo-038754	Gadus morhua	78.07	0.00e+00	1214.00
IUUC-Ggr-040003	Gaeumannomyces graminis	35.89	2.00e-97	350.00
IUUC-Gga-041002	Gallus gallus	82.10	0.00e+00	1263.00
IUUC-Gac-041555	Gasterosteus aculeatus	80.19	0.00e+00	1224.00
IUUC-Gma-043960	Glycine max	57.97	0.00e+00	837.00
IUUC-Ggo-045468	Gorilla gorilla	81.60	0.00e+00	1202.00
IUUC-Hsa-046848	Homo sapiens	81.83	0.00e+00	1261.00
IUUC-Itr-048365	Ictidomys tridecemlineatus	81.43	0.00e+00	1252.00
IUUC-Lch-050417	Latimeria chalumnae	82.94	0.00e+00	1285.00
IUUC-Lpe-051446	Leersia perrieri	53.79	0.00e+00	811.00
IUUC-Loc-051804	Lepisosteus oculatus	85.98	0.00e+00	1335.00
IUUC-Lma-053080	Leptosphaeria maculans	36.02	4.00e-130	459.00
IUUC-Laf-053701	Loxodonta africana	80.78	0.00e+00	1240.00
IUUC-Mcc-055538	Macaca mulatta	80.08	0.00e+00	1223.00
IUUC-Meu-056492	Macropus eugenii	61.52	1.00e-142	500.00
IUUC-Mor-057102	Magnaporthe oryzae	35.69	4.00e-117	416.00
IUUC-Mpo-057342	Magnaporthe poae	37.01	6.00e-101	361.00
IUUC-Mtr-058660	Medicago truncatula	56.37	0.00e+00	820.00
IUUC-Mla-058936	Melampsora laricipopulina	39.94	3.00e-117	416.00
IUUC-Mga-059754	Meleagris gallopavo	81.88	0.00e+00	1259.00
IUUC-Mvi-060455	Microbotryum violaceum	42.01	2.00e-144	506.00
IUUC-Mmr-060870	Microcebus murinus	80.89	0.00e+00	1238.00
IUUC-Mdo-062215	Monodelphis domestica	80.31	0.00e+00	1249.00
IUUC-Mmu-063751	Mus musculus	81.43	0.00e+00	1258.00
IUUC-Mac-064443	Musa acuminata	53.64	0.00e+00	825.00
IUUC-Mpu-065903	Mustela putorius furo	81.97	0.00e+00	1261.00
IUUC-Mlu-068213	Myotis lucifugus	81.97	0.00e+00	1261.00
IUUC-Nfi-068363	Neosartorya fischeri	37.89	2.00e-135	477.00
IUUC-Ncr-068950	Neurospora crassa	36.20	1.00e-117	417.00
IUUC-Nle-069480	Nomascus leucogenys	81.83	0.00e+00	1261.00
IUUC-Opr-070671	Ochotona princeps	63.52	1.00e-105	377.00
IUUC-Oan-073607	Ornithorhynchus anatinus	82.23	0.00e+00	1264.00
IUUC-Ocu-074446	Oryctolagus cuniculus	81.94	0.00e+00	1260.00
IUUC-Oba-075198	Oryza barthii	54.43	0.00e+00	813.00
IUUC-Obr-076095	Oryza brachyantha	54.30	0.00e+00	814.00
IUUC-Ogl-077032	Oryza glaberrima	54.21	0.00e+00	815.00
IUUC-Ogu-078051	Oryza glumaepatula	54.57	0.00e+00	816.00
IUUC-Oin-079399	Oryza indica	58.38	0.00e+00	716.00
IUUC-Olo-080988	Oryza longistaminata	53.64	0.00e+00	804.00
IUUC-Ome-081600	Oryza meridionalis	53.64	0.00e+00	806.00
IUUC-Oni-082623	Oryza nivara	53.77	0.00e+00	806.00
IUUC-Opu-083762	Oryza punctata	53.54	0.00e+00	805.00
IUUC-Oru-084499	Oryza rufipogon	54.43	0.00e+00	813.00
IUUC-Ola-087101	Oryzias latipes	96.57	0.00e+00	1482.00
IUUC-Olu-087650	Ostreococcus lucimarinus	48.43	0.00e+00	632.00
IUUC-Oga-088416	Otolemur garnettii	80.48	0.00e+00	1218.00
IUUC-Oar-090230	Ovis aries	81.83	0.00e+00	1256.00
IUUC-Ptr-091153	Pan troglodytes	81.83	0.00e+00	1260.00
IUUC-Pan-091729	Papio anubis	81.83	0.00e+00	1261.00
IUUC-Psi-093773	Pelodiscus sinensis	81.44	0.00e+00	1258.00
IUUC-Pma-094678	Petromyzon marinus	77.80	0.00e+00	972.00
IUUC-Pno-094946	Phaeosphaeria nodorum	34.92	2.00e-106	380.00
IUUC-Ppa-095688	Physcomitrella patens	59.75	0.00e+00	881.00
IUUC-Pfo-097037	Poecilia formosa	96.83	0.00e+00	1484.00
IUUC-Pab-097622	Pongo abelii	82.40	0.00e+00	1206.00
IUUC-Pca-100391	Procavia capensis	75.54	0.00e+00	896.00
IUUC-Ppe-101142	Prunus persica	55.50	0.00e+00	825.00
IUUC-Pva-102974	Pteropus vampyrus	78.23	0.00e+00	930.00
IUUC-Pgr-103334	Puccinia graminis	38.05	4.00e-110	392.00
IUUC-Ptt-103903	Puccinia triticina	41.05	2.00e-96	347.00
IUUC-Pte-104167	Pyrenophora teres	34.65	2.00e-125	443.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	34.36	2.00e-123	437.00
IUUC-Rno-106119	Rattus norvegicus	81.83	0.00e+00	1264.00
IUUC-Sha-106958	Sarcophilus harrisii	80.27	0.00e+00	1243.00
IUUC-Sja-107940	Schizosaccharomyces japonicus	33.56	1.00e-108	387.00
IUUC-Spo-108109	Schizosaccharomyces pombe	32.38	1.00e-104	374.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	37.68	2.00e-123	436.00
IUUC-Smo-109313	Selaginella moellendorffii	58.83	0.00e+00	885.00
IUUC-Sit-110626	Setaria italica	53.73	0.00e+00	810.00
IUUC-Sly-111497	Solanum lycopersicum	57.83	0.00e+00	842.00
IUUC-Sar-113581	Sorex araneus	71.16	0.00e+00	884.00
IUUC-Sbi-113931	Sorghum bicolor	53.87	0.00e+00	813.00
IUUC-Sre-114943	Sporisorium reilianum	39.79	7.00e-130	458.00
IUUC-Ssc-116133	Sus scrofa	78.37	0.00e+00	1192.00
IUUC-Tgu-116462	Taeniopygia guttata	81.59	0.00e+00	1254.00
IUUC-Tru-117973	Takifugu rubripes	83.15	0.00e+00	1332.00
IUUC-Tsy-119517	Tarsius syrichta	90.26	0.00e+00	662.00
IUUC-Tni-119798	Tetraodon nigroviridis	95.77	0.00e+00	1471.00
IUUC-Tca-121626	Theobroma cacao	57.14	0.00e+00	827.00
IUUC-Tre-121907	Trichoderma reesei	38.63	9.00e-128	451.00
IUUC-Tvi-122568	Trichoderma virens	38.64	2.00e-127	450.00
IUUC-Tae-123442	Triticum aestivum	54.85	0.00e+00	818.00
IUUC-Tur-126032	Triticum urartu	55.07	0.00e+00	817.00
IUUC-Tme-127162	Tuber melanosporum	38.99	4.00e-130	459.00
IUUC-Tbe-127658	Tupaia belangeri	79.41	0.00e+00	1197.00
IUUC-Ttr-129112	Tursiops truncatus	75.37	0.00e+00	1127.00
IUUC-Uma-129531	Ustilago maydis	38.57	8.00e-111	394.00
IUUC-Vda-129701	Verticillium dahliae	37.94	9.00e-133	467.00
IUUC-Vpa-130217	Vicugna pacos	73.89	0.00e+00	1107.00
IUUC-Vvi-131133	Vitis vinifera	57.24	0.00e+00	840.00
IUUC-Xtr-132724	Xenopus tropicalis	80.24	0.00e+00	1229.00
IUUC-Xma-134069	Xiphophorus maculatus	93.17	0.00e+00	1399.00
IUUC-Zma-135529	Zea mays	55.21	0.00e+00	815.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence