iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013090

Ensembl Protein ID

ENSBTAP00000044968.3

UniProt Accession

Q32LL5; INT12_BOVIN

Genbank Protein ID

AAI09521.1

Protein Name

Integrator complex subunit 12; PHD finger protein 22

Genbank Nucleotide ID

BC109520

Gene Name

INTS12; PHF22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000033648.3	ENSBTAT00000047799.3	ENSBTAP00000044968.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-08	34.2	162	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
           C vC++ +  +  +lveC++C++ +H++C+k++v ++  ++ +  w+C +C++
   Q: 162  CVVCRQMTVASGnQLVECQECHNLYHQDCHKPQVTDKEVTDPRlvWYCARCTR 214
           ******9988756********************877776665678******86 PP

Organism

Bos taurus

Functional Description
(View)

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity).

Protein Sequence
(Fasta)

MAAAVNLELD PIFLKALGFL HSKSKDSAEK LKTLLDESLA RGIDSSYRPS QKDVEPPKIS 60
STKTVSVKQE PKTSSSLPSG NNNGKVLTTE KVKKEGEKRP ADKMKSDITE GADVPKKPRL 120

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Nucleotide Sequence
(Fasta)

GGTTCGCCAG GCCACCGGCA ACGGACGGAG CAGCTGGGCG GAGCGGTGAA TAGTGAGTAG 60
TGACCTGCTG CCGGCTCTCA GCCGACTCTC AGGGGCTTCA GACCTCCGCG AGGGGCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0032039--C:integrator complex
GO:0008270--F:zinc ion binding
GO:0016180--P:snRNA processing

KEGG

bta:517489

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001485	Ailuropoda melanoleuca	91.35	6.00e-175	606.00
IUUC-Apl-003539	Anas platyrhynchos	78.37	3.00e-152	531.00
IUUC-Cja-019984	Callithrix jacchus	91.35	3.00e-165	575.00
IUUC-Cfa-020068	Canis familiaris	92.24	2.00e-180	625.00
IUUC-Cpo-021446	Cavia porcellus	85.81	9.00e-147	513.00
IUUC-Csa-023385	Chlorocebus sabaeus	91.57	2.00e-172	598.00
IUUC-Cho-025018	Choloepus hoffmanni	91.80	7.00e-165	573.00
IUUC-Dre-027546	Danio rerio	56.81	8.00e-97	347.00
IUUC-Dno-029989	Dasypus novemcinctus	91.57	4.00e-163	567.00
IUUC-Eca-033999	Equus caballus	90.24	2.00e-164	571.00
IUUC-Fca-035522	Felis catus	92.90	7.00e-173	600.00
IUUC-Gga-041056	Gallus gallus	75.99	2.00e-153	535.00
IUUC-Gac-042508	Gasterosteus aculeatus	58.46	3.00e-89	322.00
IUUC-Ggo-044647	Gorilla gorilla	90.98	4.00e-131	461.00
IUUC-Hsa-046655	Homo sapiens	91.80	1.00e-162	566.00
IUUC-Loc-052933	Lepisosteus oculatus	60.47	1.00e-100	360.00
IUUC-Laf-054471	Loxodonta africana	92.24	1.00e-174	605.00
IUUC-Mcc-055568	Macaca mulatta	91.57	2.00e-172	598.00
IUUC-Meu-056037	Macropus eugenii	87.64	1.00e-150	525.00
IUUC-Mga-059569	Meleagris gallopavo	74.67	2.00e-151	528.00
IUUC-Mmr-061180	Microcebus murinus	93.57	9.00e-167	579.00
IUUC-Mdo-062528	Monodelphis domestica	79.87	3.00e-156	545.00
IUUC-Mmu-064122	Mus musculus	90.47	4.00e-155	541.00
IUUC-Mpu-066477	Mustela putorius furo	92.46	5.00e-167	580.00
IUUC-Mlu-067391	Myotis lucifugus	92.90	5.00e-164	570.00
IUUC-Nle-069599	Nomascus leucogenys	91.57	2.00e-155	542.00
IUUC-Opr-070713	Ochotona princeps	89.14	3.00e-144	504.00
IUUC-Ont-072565	Oreochromis niloticus	62.80	9.00e-83	300.00
IUUC-Oan-073115	Ornithorhynchus anatinus	84.76	3.00e-111	394.00
IUUC-Ocu-074717	Oryctolagus cuniculus	91.57	5.00e-163	567.00
IUUC-Ola-087458	Oryzias latipes	67.43	3.00e-88	318.00
IUUC-Oga-088704	Otolemur garnettii	92.90	2.00e-164	571.00
IUUC-Oar-089184	Ovis aries	98.89	6.00e-168	583.00
IUUC-Ptr-091021	Pan troglodytes	91.80	3.00e-167	581.00
IUUC-Pan-091963	Papio anubis	91.57	2.00e-172	598.00
IUUC-Psi-093012	Pelodiscus sinensis	77.70	2.00e-142	498.00
IUUC-Pab-097870	Pongo abelii	91.35	1.00e-162	566.00
IUUC-Pca-100164	Procavia capensis	92.24	4.00e-170	590.00
IUUC-Pva-102873	Pteropus vampyrus	92.68	4.00e-164	570.00
IUUC-Rno-104840	Rattus norvegicus	90.47	3.00e-150	525.00
IUUC-Sha-106551	Sarcophilus harrisii	85.04	4.00e-153	534.00
IUUC-Tsy-119236	Tarsius syrichta	88.03	5.00e-173	600.00
IUUC-Tni-120510	Tetraodon nigroviridis	64.71	1.00e-97	350.00
IUUC-Tbe-127947	Tupaia belangeri	84.26	9.00e-153	533.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence