iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071317

Ensembl Protein ID

ENSONIP00000022336.1

UniProt Accession

I3KMJ1; I3KMJ1_ORENI

Genbank Protein ID

ENSONIP00000022336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01049040

Gene Name

wdr37 (1 of many); wdr37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000017714.1	ENSONIT00000022356.1	ENSONIP00000022336.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-25	86.6	367	398
UBD/Beta-Prp	7.80e-45	153.7	278	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlr 31
           gHtd vt+  f+  + +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFTMgDNVVSGSDDRTVKVWDLK 398
           8*******99*444669*************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtl 90
           tl++ h++v+ + ++  ++++++t+s+d+   ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v ++
   Q: 278  TLRS-HQGVVIAADWLVGGKQVVTASWDRAANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVF 365
           4444.5556666999999*************************************************************665422889* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtlt 176
           +gh+d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v+ ++++++  +++r+vrl+d+   + ++l r  +
   Q: 366  QGHTDTVTSAVFTM-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRISVSVNQKIIALPHDNRQVRLFDMsgvRLARLPRSNR 452
           *********98888.********************99987.77788999***************************7777788888888 PP
   S: 177  gghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
           +gh ++v + ++ ++     l +++ d++ + w++ 
   Q: 453  QGHRRMVCCSAWCEDNttCNLFTCGFDRQAIGWNIN 488
           88*********87777456789***********986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPVESGSSAA ARQAKQKRKS HSLSIRRTNS TEQDRSGLQR DMLEGQDSKL PLSLRSNLLD 60
LFSQIEREFE NLYIENLELR REIETLNDRL AAEGQTFEGA DLAKGALKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGTGG AGAGCGGGAG TAGCGCTGCT GCCCGCCAGG CCAAGCAGAA GAGGAAGTCC 60
CACAGCCTGT CCATCCGCAG GACCAACAGC ACCGAGCAGG ACCGCTCCGG CCTGCAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	85.28	0.00e+00	874.00
IUUC-Apl-003647	Anas platyrhynchos	87.10	0.00e+00	882.00
IUUC-Aca-004759	Anolis carolinensis	87.10	0.00e+00	895.00
IUUC-Ame-011103	Astyanax mexicanus	59.52	4.00e-153	534.00
IUUC-Bta-012718	Bos taurus	85.89	0.00e+00	872.00
IUUC-Cja-019492	Callithrix jacchus	86.29	0.00e+00	895.00
IUUC-Cfa-020199	Canis familiaris	85.28	0.00e+00	892.00
IUUC-Cpo-022500	Cavia porcellus	80.04	0.00e+00	837.00
IUUC-Csa-023567	Chlorocebus sabaeus	86.29	0.00e+00	894.00
IUUC-Cho-025071	Choloepus hoffmanni	60.28	1.00e-162	566.00
IUUC-Csv-026042	Ciona savignyi	46.40	6.00e-108	384.00
IUUC-Dre-028214	Danio rerio	91.33	0.00e+00	921.00
IUUC-Dno-029826	Dasypus novemcinctus	87.47	0.00e+00	771.00
IUUC-Dor-030967	Dipodomys ordii	85.87	0.00e+00	805.00
IUUC-Dme-031936	Drosophila melanogaster	49.27	6.00e-117	414.00
IUUC-Ete-032452	Echinops telfairi	83.27	0.00e+00	863.00
IUUC-Eca-033278	Equus caballus	85.89	0.00e+00	895.00
IUUC-Eeu-034592	Erinaceus europaeus	73.04	0.00e+00	727.00
IUUC-Fca-036431	Felis catus	85.92	0.00e+00	894.00
IUUC-Fal-037149	Ficedula albicollis	86.49	0.00e+00	883.00
IUUC-Gga-041099	Gallus gallus	86.90	0.00e+00	885.00
IUUC-Gac-042374	Gasterosteus aculeatus	95.20	0.00e+00	918.00
IUUC-Ggo-044683	Gorilla gorilla	79.64	0.00e+00	814.00
IUUC-Hsa-046658	Homo sapiens	85.48	0.00e+00	887.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	87.03	0.00e+00	835.00
IUUC-Lch-050571	Latimeria chalumnae	82.16	0.00e+00	859.00
IUUC-Loc-052652	Lepisosteus oculatus	85.11	0.00e+00	891.00
IUUC-Laf-053712	Loxodonta africana	85.37	0.00e+00	889.00
IUUC-Mcc-055521	Macaca mulatta	86.29	0.00e+00	894.00
IUUC-Meu-056324	Macropus eugenii	83.06	0.00e+00	828.00
IUUC-Mga-060114	Meleagris gallopavo	87.10	0.00e+00	891.00
IUUC-Mmr-061176	Microcebus murinus	86.09	0.00e+00	891.00
IUUC-Mdo-061888	Monodelphis domestica	87.90	0.00e+00	865.00
IUUC-Mmu-063977	Mus musculus	86.09	0.00e+00	902.00
IUUC-Mpu-066220	Mustela putorius furo	72.99	4.00e-159	554.00
IUUC-Mlu-068155	Myotis lucifugus	86.69	0.00e+00	903.00
IUUC-Nle-069964	Nomascus leucogenys	85.69	0.00e+00	889.00
IUUC-Opr-070925	Ochotona princeps	81.16	2.00e-129	455.00
IUUC-Oan-072952	Ornithorhynchus anatinus	87.70	0.00e+00	892.00
IUUC-Ocu-073913	Oryctolagus cuniculus	86.09	0.00e+00	900.00
IUUC-Ola-087024	Oryzias latipes	94.37	0.00e+00	978.00
IUUC-Oga-087945	Otolemur garnettii	85.69	0.00e+00	897.00
IUUC-Oar-089854	Ovis aries	86.09	0.00e+00	866.00
IUUC-Ptr-091486	Pan troglodytes	85.69	0.00e+00	888.00
IUUC-Pan-091738	Papio anubis	86.29	0.00e+00	894.00
IUUC-Psi-093953	Pelodiscus sinensis	86.49	0.00e+00	883.00
IUUC-Pma-094560	Petromyzon marinus	73.86	0.00e+00	775.00
IUUC-Pfo-097222	Poecilia formosa	93.15	0.00e+00	905.00
IUUC-Pab-098778	Pongo abelii	81.25	0.00e+00	832.00
IUUC-Pca-100852	Procavia capensis	82.46	0.00e+00	838.00
IUUC-Pva-103130	Pteropus vampyrus	85.12	1.00e-121	430.00
IUUC-Rno-105848	Rattus norvegicus	78.43	0.00e+00	796.00
IUUC-Sha-106750	Sarcophilus harrisii	87.50	0.00e+00	890.00
IUUC-Sar-113749	Sorex araneus	78.07	0.00e+00	795.00
IUUC-Ssc-115691	Sus scrofa	85.08	0.00e+00	852.00
IUUC-Tgu-117365	Taeniopygia guttata	86.49	0.00e+00	841.00
IUUC-Tru-117595	Takifugu rubripes	93.75	0.00e+00	920.00
IUUC-Tsy-118973	Tarsius syrichta	66.76	5.00e-134	471.00
IUUC-Tni-120545	Tetraodon nigroviridis	93.37	0.00e+00	971.00
IUUC-Tbe-127976	Tupaia belangeri	63.91	2.00e-177	615.00
IUUC-Ttr-128472	Tursiops truncatus	83.50	0.00e+00	855.00
IUUC-Xtr-132621	Xenopus tropicalis	86.90	0.00e+00	867.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence