iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106750

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01199133

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015206.1	ENSSHAT00000018060.1	ENSSHAP00000017912.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-23	80.8	367	398
UBD/Beta-Prp	3.80e-45	154.5	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQRIIALPHDNRQVRLFDMsgvRLARLPRSNRQGH 455
           ******99999.********************988874555555.55555555558*****************777778888888888* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           ************9777899***********986 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPTESGSCAT ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQTIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCTAAGAA GAAAAGCAAA AACAAAAAAA ACAAACAATT TTCATTCTTC CCCACCTTTT 60
TTTCTGTTTA GCACATTGCA GGAGAAACAG GACATTATTT TCTAGAAGTA ATGCCCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

shr:100930541

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	93.75	0.00e+00	951.00
IUUC-Apl-003647	Anas platyrhynchos	95.56	0.00e+00	953.00
IUUC-Aca-004759	Anolis carolinensis	95.56	0.00e+00	967.00
IUUC-Ame-011103	Astyanax mexicanus	56.35	1.00e-144	506.00
IUUC-Bta-012718	Bos taurus	92.74	0.00e+00	942.00
IUUC-Cel-018499	Caenorhabditis elegans	41.78	2.00e-95	342.00
IUUC-Cja-019492	Callithrix jacchus	94.35	0.00e+00	972.00
IUUC-Cfa-020199	Canis familiaris	93.15	0.00e+00	969.00
IUUC-Cpo-022500	Cavia porcellus	88.71	0.00e+00	923.00
IUUC-Csa-023567	Chlorocebus sabaeus	95.16	0.00e+00	979.00
IUUC-Cho-025071	Choloepus hoffmanni	67.94	0.00e+00	639.00
IUUC-Cin-025460	Ciona intestinalis	45.51	1.00e-104	373.00
IUUC-Csv-026042	Ciona savignyi	46.21	7.00e-108	383.00
IUUC-Dre-028214	Danio rerio	83.87	0.00e+00	871.00
IUUC-Dno-029826	Dasypus novemcinctus	96.39	0.00e+00	832.00
IUUC-Dor-030967	Dipodomys ordii	94.70	0.00e+00	881.00
IUUC-Dme-031936	Drosophila melanogaster	48.95	2.00e-117	415.00
IUUC-Ete-032452	Echinops telfairi	92.74	0.00e+00	952.00
IUUC-Eca-033278	Equus caballus	93.35	0.00e+00	971.00
IUUC-Eeu-034592	Erinaceus europaeus	81.85	0.00e+00	815.00
IUUC-Fca-036431	Felis catus	93.76	0.00e+00	972.00
IUUC-Fal-037149	Ficedula albicollis	94.15	0.00e+00	943.00
IUUC-Gmo-038476	Gadus morhua	81.52	0.00e+00	780.00
IUUC-Gga-041099	Gallus gallus	95.16	0.00e+00	952.00
IUUC-Gac-042374	Gasterosteus aculeatus	85.80	0.00e+00	838.00
IUUC-Ggo-044683	Gorilla gorilla	86.90	0.00e+00	884.00
IUUC-Hsa-046658	Homo sapiens	94.35	0.00e+00	973.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.38	0.00e+00	906.00
IUUC-Lch-050571	Latimeria chalumnae	86.34	0.00e+00	899.00
IUUC-Loc-052652	Lepisosteus oculatus	83.78	0.00e+00	877.00
IUUC-Laf-053712	Loxodonta africana	94.39	0.00e+00	974.00
IUUC-Mcc-055521	Macaca mulatta	95.16	0.00e+00	979.00
IUUC-Meu-056324	Macropus eugenii	94.15	0.00e+00	917.00
IUUC-Mga-060114	Meleagris gallopavo	95.36	0.00e+00	958.00
IUUC-Mmr-061176	Microcebus murinus	94.35	0.00e+00	970.00
IUUC-Mdo-061888	Monodelphis domestica	98.79	0.00e+00	952.00
IUUC-Mmu-063977	Mus musculus	95.36	0.00e+00	989.00
IUUC-Mpu-066220	Mustela putorius furo	80.75	2.00e-175	608.00
IUUC-Mlu-068155	Myotis lucifugus	93.75	0.00e+00	974.00
IUUC-Nle-069964	Nomascus leucogenys	94.56	0.00e+00	974.00
IUUC-Opr-070925	Ochotona princeps	92.03	1.00e-145	509.00
IUUC-Ont-071317	Oreochromis niloticus	87.50	0.00e+00	864.00
IUUC-Oan-072952	Ornithorhynchus anatinus	97.38	0.00e+00	974.00
IUUC-Ocu-073913	Oryctolagus cuniculus	95.36	0.00e+00	987.00
IUUC-Ola-087024	Oryzias latipes	85.11	0.00e+00	890.00
IUUC-Oga-087945	Otolemur garnettii	93.95	0.00e+00	981.00
IUUC-Oar-089854	Ovis aries	93.15	0.00e+00	938.00
IUUC-Ptr-091486	Pan troglodytes	94.56	0.00e+00	974.00
IUUC-Pan-091738	Papio anubis	95.16	0.00e+00	979.00
IUUC-Psi-093953	Pelodiscus sinensis	95.97	0.00e+00	964.00
IUUC-Pma-094560	Petromyzon marinus	74.46	0.00e+00	775.00
IUUC-Pfo-097222	Poecilia formosa	83.87	0.00e+00	834.00
IUUC-Pab-098778	Pongo abelii	90.12	0.00e+00	914.00
IUUC-Pca-100852	Procavia capensis	91.13	0.00e+00	924.00
IUUC-Pva-103130	Pteropus vampyrus	92.98	6.00e-133	467.00
IUUC-Rno-105848	Rattus norvegicus	86.09	0.00e+00	870.00
IUUC-Sar-113749	Sorex araneus	85.28	0.00e+00	860.00
IUUC-Ssc-115691	Sus scrofa	91.94	0.00e+00	924.00
IUUC-Tgu-117365	Taeniopygia guttata	93.95	0.00e+00	899.00
IUUC-Tru-117595	Takifugu rubripes	85.69	0.00e+00	846.00
IUUC-Tsy-118973	Tarsius syrichta	73.08	2.00e-147	515.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.34	0.00e+00	879.00
IUUC-Tbe-127976	Tupaia belangeri	71.17	0.00e+00	682.00
IUUC-Ttr-128472	Tursiops truncatus	90.93	0.00e+00	930.00
IUUC-Xtr-132621	Xenopus tropicalis	92.74	0.00e+00	919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence