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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064307
UUCD1 version UUC-MuM-01146
Ensembl Protein ID ENSMUSP00000059927.8
UniProt Accession Q76N33; Q76LY0; Q8VEK5; STALP_MOUSE
Genbank Protein ID BAD00166.1; BAD00167.1; BAD00168.1; BAD06408.1; BAD06409.1; AAH18343.1
Protein Name AMSH-like protease; AMSH family protein; STAM-binding protein-like 1
Genbank Nucleotide ID AB066211; AB066212; AB066213; AB010121; AB010122; BC018343
Gene Name Stambpl1; Amshlp; Amsh-lp
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000024776.17 ENSMUST00000054956.14 ENSMUSP00000059927.8
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Jab_MPN 6.90e-51 172.9 268 393
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Jab_MPN
   S: 5    vvvlpkrllkkflelsdvkiavavevyGlllgelvkdkevktvvlvpkqlagvgsvqvenvedvfdlldqeGlivlGWiHthpeelkfl 93
            vvl++ l++kfl l+d+++ +++e++G+l+g+l ++++++t+v+vpkq+ag ++++venve++f+++dq+Gl +lGWiHthp++++fl
   Q: 268  CVVLSRDLCHKFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELFNVQDQHGLLTLGWIHTHPTQTAFL 356
           69*************************************************************************************** PP
   S: 94   ssvdvathsslealkkrsvaivsspkfqelsafkltd 130
           ssvd++th+s++ ++++ +aiv+spk +++++f+lt+
   Q: 357  SSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTN 393
           ***********************************96 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity).
 Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity).
Protein Sequence
(Fasta)
MEQPFTVNSL KKLAAMPDHT DVSLSPEERV RALSKLGCNI SINEDITPRR YFRSGVEMER 60
MASVYLEEGN LENAFVLYNK FITLFVEKLP SHRDYQQCAV PEKQDIMKKL KEIAFPRTDE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064307|UBD,Jab_MPN|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGGCGGAC CATCGCTGTG ACAATTTCAT TCCCTACGTT GCTGCGGCAG AGATTCAGAG 60
GCCATTGGCC TGTGCGTTGT TTTGCAAGGG AGCTGGGGCT GTCCCGCCAG ACAGAAGAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064307|UBD,Jab_MPN|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
Interpro

IPR000555--JAMM/MPN+_dom
IPR007330--MIT
IPR015063--USP8_dimer
Pfam

PF01398--JAB
PF08969--USP8_dimer
SMART

SM00232--JAB_MPN
Gene Ontology

GO:0016020--C:membrane
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity
KEGG mmu:76630
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000506 Aegilops tauschii 49.70 2.00e-42 167.00
IUUC-Aml-001297 Ailuropoda melanoleuca 88.07 0.00e+00 770.00
IUUC-Apl-003560 Anas platyrhynchos 79.13 0.00e+00 691.00
IUUC-Aca-004523 Anolis carolinensis 80.78 0.00e+00 679.00
IUUC-Ath-007385 Arabidopsis thaliana 45.66 7.00e-43 168.00
IUUC-Ame-011650 Astyanax mexicanus 67.12 3.00e-159 554.00
IUUC-Bta-012468 Bos taurus 88.99 0.00e+00 822.00
IUUC-Bdi-014845 Brachypodium distachyon 49.41 2.00e-42 167.00
IUUC-Cja-019809 Callithrix jacchus 91.06 0.00e+00 801.00
IUUC-Cfa-020729 Canis familiaris 86.47 0.00e+00 759.00
IUUC-Cpo-022124 Cavia porcellus 90.83 0.00e+00 800.00
IUUC-Cre-022989 Chlamydomonas reinhardtii 47.78 5.00e-34 137.00
IUUC-Csa-023702 Chlorocebus sabaeus 87.00 0.00e+00 774.00
IUUC-Cho-024802 Choloepus hoffmanni 83.73 0.00e+00 697.00
IUUC-Dre-027852 Danio rerio 67.35 1.00e-165 576.00
IUUC-Dno-029491 Dasypus novemcinctus 91.23 0.00e+00 785.00
IUUC-Dor-030785 Dipodomys ordii 90.93 0.00e+00 749.00
IUUC-Dse-031153 Dothistroma septosporum 48.07 9.00e-38 151.00
IUUC-Ete-032842 Echinops telfairi 86.40 0.00e+00 764.00
IUUC-Eca-034082 Equus caballus 89.91 0.00e+00 832.00
IUUC-Eeu-034738 Erinaceus europaeus 75.67 1.00e-166 578.00
IUUC-Fca-036175 Felis catus 88.76 0.00e+00 778.00
IUUC-Fal-037252 Ficedula albicollis 80.28 0.00e+00 702.00
IUUC-Gga-041246 Gallus gallus 77.98 0.00e+00 679.00
IUUC-Gma-042650 Glycine max 45.05 9.00e-46 177.00
IUUC-Ggo-044665 Gorilla gorilla 82.50 0.00e+00 702.00
IUUC-Hsa-046463 Homo sapiens 91.06 0.00e+00 798.00
IUUC-Itr-047930 Ictidomys tridecemlineatus 91.51 0.00e+00 807.00
IUUC-Kpa-049381 Komagataella pastoris 30.84 3.00e-47 182.00
IUUC-Lch-049954 Latimeria chalumnae 78.52 0.00e+00 692.00
IUUC-Lpe-051096 Leersia perrieri 50.60 6.00e-43 168.00
IUUC-Loc-052178 Lepisosteus oculatus 69.86 6.00e-177 613.00
IUUC-Laf-053366 Loxodonta africana 90.60 0.00e+00 797.00
IUUC-Mcc-055560 Macaca mulatta 89.15 0.00e+00 768.00
IUUC-Mtr-057642 Medicago truncatula 47.40 1.00e-44 174.00
IUUC-Mga-059433 Meleagris gallopavo 78.21 0.00e+00 680.00
IUUC-Mmr-061327 Microcebus murinus 87.39 0.00e+00 756.00
IUUC-Mdo-062783 Monodelphis domestica 75.21 4.00e-148 517.00
IUUC-Mac-065572 Musa acuminata 48.00 4.00e-44 172.00
IUUC-Mpu-066259 Mustela putorius furo 88.07 0.00e+00 774.00
IUUC-Mlu-067657 Myotis lucifugus 89.68 0.00e+00 794.00
IUUC-Nle-069180 Nomascus leucogenys 89.89 0.00e+00 779.00
IUUC-Opr-070830 Ochotona princeps 91.15 0.00e+00 766.00
IUUC-Ont-071929 Oreochromis niloticus 61.76 7.00e-146 510.00
IUUC-Oan-073314 Ornithorhynchus anatinus 77.75 1.00e-169 589.00
IUUC-Ocu-074386 Oryctolagus cuniculus 91.28 0.00e+00 802.00
IUUC-Oba-075358 Oryza barthii 50.60 1.00e-42 166.00
IUUC-Obr-076024 Oryza brachyantha 51.81 2.00e-43 170.00
IUUC-Ogl-077100 Oryza glaberrima 49.70 8.00e-42 164.00
IUUC-Ogu-078047 Oryza glumaepatula 50.60 9.00e-43 168.00
IUUC-Oin-079545 Oryza indica 50.60 1.00e-42 167.00
IUUC-Olo-080359 Oryza longistaminata 50.60 9.00e-43 167.00
IUUC-Ome-081619 Oryza meridionalis 50.60 1.00e-42 167.00
IUUC-Oni-082079 Oryza nivara 50.60 1.00e-42 167.00
IUUC-Opu-083914 Oryza punctata 49.70 1.00e-41 164.00
IUUC-Oru-085251 Oryza rufipogon 50.60 7.00e-43 168.00
IUUC-Osa-085426 Oryza sativa 50.60 1.00e-42 167.00
IUUC-Ola-087457 Oryzias latipes 72.66 1.00e-55 208.00
IUUC-Oga-088150 Otolemur garnettii 90.09 0.00e+00 760.00
IUUC-Oar-089824 Ovis aries 87.33 0.00e+00 812.00
IUUC-Ptr-090702 Pan troglodytes 90.83 0.00e+00 796.00
IUUC-Pan-091924 Papio anubis 91.06 0.00e+00 793.00
IUUC-Psi-093069 Pelodiscus sinensis 80.96 0.00e+00 679.00
IUUC-Pno-094896 Phaeosphaeria nodorum 51.35 4.00e-38 153.00
IUUC-Pab-098080 Pongo abelii 90.60 0.00e+00 797.00
IUUC-Pca-100352 Procavia capensis 91.15 0.00e+00 766.00
IUUC-Rno-104938 Rattus norvegicus 97.48 0.00e+00 846.00
IUUC-Sha-107154 Sarcophilus harrisii 83.72 0.00e+00 770.00
IUUC-Sja-107679 Schizosaccharomyces japonicus 33.41 1.00e-50 194.00
IUUC-Spo-108166 Schizosaccharomyces pombe 55.77 2.00e-44 173.00
IUUC-Smo-109437 Selaginella moellendorffii 48.84 8.00e-42 162.00
IUUC-Sit-110118 Setaria italica 44.44 7.00e-44 171.00
IUUC-Sly-111816 Solanum lycopersicum 47.40 2.00e-43 170.00
IUUC-Stu-112240 Solanum tuberosum 47.40 3.00e-43 169.00
IUUC-Sar-112924 Sorex araneus 90.43 0.00e+00 737.00
IUUC-Sbi-114439 Sorghum bicolor 45.02 7.00e-43 168.00
IUUC-Ssc-115372 Sus scrofa 90.83 0.00e+00 802.00
IUUC-Tsy-119100 Tarsius syrichta 85.27 1.00e-171 596.00
IUUC-Tae-124826 Triticum aestivum 50.00 5.00e-43 168.00
IUUC-Tur-126001 Triticum urartu 50.00 8.00e-43 168.00
IUUC-Tme-126874 Tuber melanosporum 53.38 2.00e-43 170.00
IUUC-Tbe-127977 Tupaia belangeri 89.91 4.00e-180 624.00
IUUC-Ttr-128291 Tursiops truncatus 90.89 0.00e+00 697.00
IUUC-Vpa-130821 Vicugna pacos 91.42 0.00e+00 755.00
IUUC-Vvi-131576 Vitis vinifera 30.35 2.00e-50 193.00
IUUC-Xma-133318 Xiphophorus maculatus 61.12 3.00e-148 518.00
IUUC-Yli-134641 Yarrowia lipolytica 49.70 8.00e-45 174.00
Created Date 25-Jun-2017

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