iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101392

Ensembl Protein ID

EMJ14495

UniProt Accession

M5X602; M5X602_PRUPE

Genbank Protein ID

EMJ14495.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KB639078

Gene Name

PRUPE_ppa000388mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa000388mg	EMJ14495	EMJ14495

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-37	124.9	50	85
UBD/Beta-Prp	5.10e-76	256.2	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++ +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhTSqPLFVSGGDDYKIKVWNYKLHRC 85
           99********9556****************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHTSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...........................ktgkllrtltgg 178
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+ +hp+++l+vs+slD+tvr+Wd+                             + + + l+g 
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCALFHPKEDLVVSASLDQTVRVWDIgalrkktvapaddilrlsqmnadffggVDAVVKYVLEG- 202
           **************************.**************************************************66666666666333333344466. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           h++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ l+t+ +++++++  a+ +++ 
   Q: 203  HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVLFHARQDIIVSNSEDRSIRVWDATKRTGLQTFRREHDRFWILAA-HPEM 302
           ********************************777668**********************************************************.6666 PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n l++g  ds   ++kl++++p
   Q: 303  NLLAAG-HDSGMIVFKLERERP 323
           655555.689999999988765 PP

Organism

Prunus persica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
TSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACGA AATTCGAGAC CAAGAGTAAT CGAGTGAAGG GGCTGAGCTT TCACAGCAAG 60
AGGCCATGGA TCTTGGCCAG TCTCCACAGC GGTGTGATCC AGCTCTGGGA TTACCGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

pper:PRUPE_ppa000388mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	79.00	0.00e+00	1986.00
IUUC-Ago-007992	Ashbya gossypii	43.40	0.00e+00	954.00
IUUC-Bdi-014549	Brachypodium distachyon	78.61	0.00e+00	2020.00
IUUC-Cel-018115	Caenorhabditis elegans	55.94	0.00e+00	942.00
IUUC-Cin-025572	Ciona intestinalis	51.12	0.00e+00	1236.00
IUUC-Hvu-047556	Hordeum vulgare	79.26	0.00e+00	2017.00
IUUC-Kpa-049256	Komagataella pastoris	44.60	0.00e+00	1031.00
IUUC-Lpe-051316	Leersia perrieri	79.43	0.00e+00	1993.00
IUUC-Mla-059019	Melampsora laricipopulina	50.93	0.00e+00	1224.00
IUUC-Mac-065398	Musa acuminata	75.51	0.00e+00	1878.00
IUUC-Obr-076429	Oryza brachyantha	77.81	0.00e+00	1974.00
IUUC-Ome-081668	Oryza meridionalis	84.84	0.00e+00	1274.00
IUUC-Opu-083885	Oryza punctata	80.66	0.00e+00	2005.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.74	0.00e+00	1568.00
IUUC-Pca-100413	Procavia capensis	60.79	0.00e+00	695.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.29	0.00e+00	928.00
IUUC-Sit-109697	Setaria italica	81.00	0.00e+00	2010.00
IUUC-Sly-111759	Solanum lycopersicum	86.54	0.00e+00	2202.00
IUUC-Stu-112564	Solanum tuberosum	86.37	0.00e+00	2197.00
IUUC-Sbi-114388	Sorghum bicolor	80.80	0.00e+00	2010.00
IUUC-Tca-121046	Theobroma cacao	89.51	0.00e+00	2229.00
IUUC-Tae-125527	Triticum aestivum	79.16	0.00e+00	1997.00
IUUC-Tur-126754	Triticum urartu	77.52	0.00e+00	1944.00
IUUC-Tbe-127882	Tupaia belangeri	68.71	6.00e-128	451.00
IUUC-Vvi-130958	Vitis vinifera	89.07	0.00e+00	2211.00
IUUC-Yli-134399	Yarrowia lipolytica	42.56	0.00e+00	965.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence