iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tre-121951

Ensembl Protein ID

EGR48167

UniProt Accession

G0RKM5; G0RKM5_HYPJQ

Genbank Protein ID

EGR48167.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

GL985065

Gene Name

TRIREDRAFT_121966

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIREDRAFT_121966	EGR48167	EGR48167

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-34	114.9	56	92
UBD/Beta-Prp	3.50e-77	258.4	9	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW++ t ++l
   Q: 56   HDGPVRGVDFhKTqPLFVSGGDDYKIKVWSYQTRRCL 92
           99*********4459***************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ v+f+++++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++ f+ 
   Q: 9    TKFESKSSRAKGIAFHPKRPWILVALHSSTIQLWDYRMGTLIDRFEEHDGPVRGVDFHKTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFHH 109
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllrt 174
           +  +++s+s+d+tir+w++++++ +  t +gh++  +c+++hp+++l+vs+slD+ vr+Wd+                               +t+ +++ 
   Q: 110  ELPWILSASDDQTIRIWNWQNRSLIC-TMTGHNHYAMCAQFHPKEDLVVSASLDQSVRVWDIsglrkkhsaptsmsyedqiaranqnqtdmfgNTDAVVKF 209
           *************************9.*********************************************************99999999777777776 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
             +gh++ v++++f+++++ +vs+++d+ vklw +++++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl +++ +++++++n++++ +a+ 
   Q: 210  VLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAweVDTCRGHFQNASGCLFHPHQDLILSAGEDKTIRVWDLNKRTAVQSFKRENDRFWVIAA- 309
           6777********************************888778**********************************************************. PP
   S: 274  sfgdnvlvlgsedskvniwklkknep 299
           +++ n +++g  d+ v+++kl++++p
   Q: 310  HPEINLFAAG-HDNGVMVFKLERERP 334
           6666555555.478*******98775 PP

Organism

Trichoderma reesei

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQSSPGMLTK FESKSSRAKG IAFHPKRPWI LVALHSSTIQ LWDYRMGTLI DRFEEHDGPV 60
RGVDFHKTQP LFVSGGDDYK IKVWSYQTRR CLFTLNGHLD YVRTVFFHHE LPWILSASDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGTCCT CCCCAGGAAT GTTGACCAAG GTACGTTGCC TATCCGAGAG CTGCTCGGCT 60
CCGGGATCCT CAACTGACGC CCCTCCAGTT TGAGTCGAAG TCGTCCAGGG CCAAAGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

tre:TRIREDRAFT_121966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	55.86	0.00e+00	990.00
IUUC-Aml-001758	Ailuropoda melanoleuca	49.08	0.00e+00	1223.00
IUUC-Atr-002493	Amborella trichopoda	47.09	0.00e+00	1100.00
IUUC-Apl-003385	Anas platyrhynchos	43.88	0.00e+00	913.00
IUUC-Aca-005154	Anolis carolinensis	71.09	4.00e-94	335.00
IUUC-Aly-006020	Arabidopsis lyrata	54.26	0.00e+00	959.00
IUUC-Ath-007360	Arabidopsis thaliana	54.97	0.00e+00	969.00
IUUC-Ago-007992	Ashbya gossypii	50.61	0.00e+00	1225.00
IUUC-Acl-008027	Aspergillus clavatus	75.68	0.00e+00	1923.00
IUUC-Afl-008644	Aspergillus flavus	76.64	0.00e+00	1929.00
IUUC-Afu-008964	Aspergillus fumigatus	76.54	0.00e+00	1948.00
IUUC-Ani-009379	Aspergillus nidulans	82.37	0.00e+00	1512.00
IUUC-Ang-009756	Aspergillus niger	75.88	0.00e+00	1933.00
IUUC-Aor-010174	Aspergillus oryzae	76.56	0.00e+00	1925.00
IUUC-Ate-010302	Aspergillus terreus	75.53	0.00e+00	1959.00
IUUC-Ame-011229	Astyanax mexicanus	57.45	0.00e+00	1016.00
IUUC-Bgr-012300	Blumeria graminis	76.55	0.00e+00	1932.00
IUUC-Bta-012524	Bos taurus	49.44	0.00e+00	1217.00
IUUC-Bci-013781	Botrytis cinerea	82.12	0.00e+00	2085.00
IUUC-Bdi-014549	Brachypodium distachyon	45.77	0.00e+00	1114.00
IUUC-Bol-015925	Brassica oleracea	55.33	0.00e+00	968.00
IUUC-Bra-016978	Brassica rapa	54.85	0.00e+00	962.00
IUUC-Cel-018115	Caenorhabditis elegans	51.65	0.00e+00	902.00
IUUC-Cja-019107	Callithrix jacchus	48.12	0.00e+00	1200.00
IUUC-Cfa-020675	Canis familiaris	48.78	0.00e+00	1196.00
IUUC-Cpo-021813	Cavia porcellus	49.52	0.00e+00	1233.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.31	0.00e+00	1004.00
IUUC-Csa-023523	Chlorocebus sabaeus	49.36	0.00e+00	1236.00
IUUC-Cho-024704	Choloepus hoffmanni	63.58	7.00e-123	433.00
IUUC-Cin-025572	Ciona intestinalis	48.71	0.00e+00	1172.00
IUUC-Csv-025864	Ciona savignyi	55.37	0.00e+00	953.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	86.48	0.00e+00	2151.00
IUUC-Cne-027053	Cryptococcus neoformans	54.72	0.00e+00	1330.00
IUUC-Cme-027222	Cyanidioschyzon merolae	38.65	3.00e-139	488.00
IUUC-Dre-027421	Danio rerio	49.64	0.00e+00	1214.00
IUUC-Dno-029303	Dasypus novemcinctus	49.88	0.00e+00	1235.00
IUUC-Dor-030290	Dipodomys ordii	46.50	4.00e-147	514.00
IUUC-Dse-031543	Dothistroma septosporum	73.96	0.00e+00	1804.00
IUUC-Dme-031945	Drosophila melanogaster	56.35	0.00e+00	964.00
IUUC-Ete-032873	Echinops telfairi	46.65	0.00e+00	1066.00
IUUC-Eca-033773	Equus caballus	48.20	0.00e+00	1186.00
IUUC-Eeu-034874	Erinaceus europaeus	37.06	6.00e-166	576.00
IUUC-Fca-035739	Felis catus	49.00	0.00e+00	1204.00
IUUC-Fal-037263	Ficedula albicollis	46.20	0.00e+00	1082.00
IUUC-Fox-037738	Fusarium oxysporum	87.30	0.00e+00	2243.00
IUUC-Fso-038153	Fusarium solani	87.79	0.00e+00	2251.00
IUUC-Gmo-039602	Gadus morhua	55.01	0.00e+00	992.00
IUUC-Ggr-039931	Gaeumannomyces graminis	83.26	0.00e+00	2077.00
IUUC-Gga-040590	Gallus gallus	48.77	0.00e+00	1229.00
IUUC-Gac-041318	Gasterosteus aculeatus	47.29	0.00e+00	1181.00
IUUC-Gma-043894	Glycine max	55.40	0.00e+00	983.00
IUUC-Ggo-045029	Gorilla gorilla	49.08	0.00e+00	1229.00
IUUC-Hsa-046078	Homo sapiens	49.08	0.00e+00	1230.00
IUUC-Hvu-047556	Hordeum vulgare	45.81	0.00e+00	1117.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	40.25	0.00e+00	660.00
IUUC-Kpa-049256	Komagataella pastoris	53.24	0.00e+00	1344.00
IUUC-Lch-049706	Latimeria chalumnae	48.99	0.00e+00	1202.00
IUUC-Lpe-051553	Leersia perrieri	54.78	0.00e+00	963.00
IUUC-Loc-051867	Lepisosteus oculatus	46.23	0.00e+00	767.00
IUUC-Lma-053138	Leptosphaeria maculans	74.34	0.00e+00	1896.00
IUUC-Laf-053510	Loxodonta africana	49.16	0.00e+00	1226.00
IUUC-Mcc-055836	Macaca mulatta	49.36	0.00e+00	1228.00
IUUC-Meu-056238	Macropus eugenii	51.91	0.00e+00	714.00
IUUC-Mor-057172	Magnaporthe oryzae	83.96	0.00e+00	2164.00
IUUC-Mpo-057300	Magnaporthe poae	83.00	0.00e+00	2094.00
IUUC-Mtr-058248	Medicago truncatula	54.92	0.00e+00	982.00
IUUC-Mla-059019	Melampsora laricipopulina	55.56	0.00e+00	1404.00
IUUC-Mga-059499	Meleagris gallopavo	48.78	0.00e+00	1224.00
IUUC-Mvi-060336	Microbotryum violaceum	54.60	0.00e+00	1384.00
IUUC-Mmr-061102	Microcebus murinus	49.24	0.00e+00	1217.00
IUUC-Mdo-062594	Monodelphis domestica	49.56	0.00e+00	1242.00
IUUC-Mmu-063736	Mus musculus	49.28	0.00e+00	1224.00
IUUC-Mac-065398	Musa acuminata	43.95	0.00e+00	1019.00
IUUC-Mpu-066701	Mustela putorius furo	48.95	0.00e+00	1219.00
IUUC-Mlu-067392	Myotis lucifugus	49.20	0.00e+00	1229.00
IUUC-Nfi-068270	Neosartorya fischeri	75.39	0.00e+00	1923.00
IUUC-Ncr-068892	Neurospora crassa	84.71	0.00e+00	2149.00
IUUC-Nle-069634	Nomascus leucogenys	60.27	0.00e+00	877.00
IUUC-Opr-070952	Ochotona princeps	37.21	1.00e-168	585.00
IUUC-Ont-072488	Oreochromis niloticus	47.85	0.00e+00	1193.00
IUUC-Ocu-074211	Oryctolagus cuniculus	49.36	0.00e+00	1229.00
IUUC-Oba-075761	Oryza barthii	55.26	0.00e+00	979.00
IUUC-Obr-076429	Oryza brachyantha	55.10	0.00e+00	979.00
IUUC-Ogl-077364	Oryza glaberrima	55.26	0.00e+00	980.00
IUUC-Ogu-078257	Oryza glumaepatula	55.26	0.00e+00	978.00
IUUC-Oin-079274	Oryza indica	55.14	0.00e+00	978.00
IUUC-Olo-080466	Oryza longistaminata	55.41	0.00e+00	972.00
IUUC-Ome-081993	Oryza meridionalis	57.33	0.00e+00	932.00
IUUC-Oni-082874	Oryza nivara	55.26	0.00e+00	979.00
IUUC-Opu-083885	Oryza punctata	55.26	0.00e+00	979.00
IUUC-Oru-084274	Oryza rufipogon	55.14	0.00e+00	978.00
IUUC-Osa-085565	Oryza sativa	55.14	0.00e+00	978.00
IUUC-Ola-086921	Oryzias latipes	48.00	0.00e+00	1187.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.03	0.00e+00	1162.00
IUUC-Oga-087991	Otolemur garnettii	47.24	0.00e+00	1159.00
IUUC-Oar-089590	Ovis aries	49.52	0.00e+00	1234.00
IUUC-Ptr-090808	Pan troglodytes	49.08	0.00e+00	1229.00
IUUC-Pan-092475	Papio anubis	48.99	0.00e+00	1224.00
IUUC-Psi-093044	Pelodiscus sinensis	52.48	0.00e+00	855.00
IUUC-Pno-094839	Phaeosphaeria nodorum	73.81	0.00e+00	1815.00
IUUC-Ppa-095785	Physcomitrella patens	49.76	0.00e+00	1219.00
IUUC-Pfo-097493	Poecilia formosa	48.22	0.00e+00	1188.00
IUUC-Pab-098497	Pongo abelii	49.36	0.00e+00	1238.00
IUUC-Pop-099992	Populus trichocarpa	55.98	0.00e+00	977.00
IUUC-Pca-100413	Procavia capensis	54.11	0.00e+00	632.00
IUUC-Ppe-101899	Prunus persica	55.93	0.00e+00	986.00
IUUC-Pva-102126	Pteropus vampyrus	47.64	0.00e+00	1167.00
IUUC-Pgr-103376	Puccinia graminis	55.52	0.00e+00	1411.00
IUUC-Ptt-103978	Puccinia triticina	49.76	0.00e+00	1193.00
IUUC-Pte-104126	Pyrenophora teres	73.43	0.00e+00	1816.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	66.26	0.00e+00	1407.00
IUUC-Rno-105428	Rattus norvegicus	49.60	0.00e+00	1235.00
IUUC-Sce-106464	Saccharomyces cerevisiae	50.58	0.00e+00	1211.00
IUUC-Sha-107301	Sarcophilus harrisii	49.14	0.00e+00	1209.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	51.76	0.00e+00	1319.00
IUUC-Spo-108217	Schizosaccharomyces pombe	54.30	0.00e+00	1384.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	82.03	0.00e+00	2081.00
IUUC-Smo-109582	Selaginella moellendorffii	57.28	0.00e+00	1021.00
IUUC-Sit-109697	Setaria italica	55.02	0.00e+00	979.00
IUUC-Sly-111759	Solanum lycopersicum	55.32	0.00e+00	986.00
IUUC-Stu-112564	Solanum tuberosum	55.32	0.00e+00	987.00
IUUC-Sar-113313	Sorex araneus	40.68	2.00e-160	557.00
IUUC-Sbi-114388	Sorghum bicolor	55.02	0.00e+00	979.00
IUUC-Sre-115209	Sporisorium reilianum	62.75	0.00e+00	1143.00
IUUC-Ssc-115933	Sus scrofa	49.52	0.00e+00	1231.00
IUUC-Tgu-117109	Taeniopygia guttata	43.00	5.00e-91	326.00
IUUC-Tru-117772	Takifugu rubripes	48.15	0.00e+00	1176.00
IUUC-Tsy-119105	Tarsius syrichta	47.97	0.00e+00	944.00
IUUC-Tni-120556	Tetraodon nigroviridis	36.49	0.00e+00	757.00
IUUC-Tca-121046	Theobroma cacao	47.25	0.00e+00	1129.00
IUUC-Tvi-122359	Trichoderma virens	95.16	0.00e+00	2360.00
IUUC-Tae-125527	Triticum aestivum	55.86	0.00e+00	990.00
IUUC-Tur-126754	Triticum urartu	55.74	0.00e+00	989.00
IUUC-Tme-127170	Tuber melanosporum	74.28	0.00e+00	1939.00
IUUC-Tbe-127882	Tupaia belangeri	63.14	2.00e-122	431.00
IUUC-Ttr-128217	Tursiops truncatus	47.48	0.00e+00	1160.00
IUUC-Uma-129337	Ustilago maydis	62.87	0.00e+00	1135.00
IUUC-Vda-129828	Verticillium dahliae	82.51	0.00e+00	2090.00
IUUC-Vpa-130537	Vicugna pacos	49.12	0.00e+00	1212.00
IUUC-Vvi-130958	Vitis vinifera	56.22	0.00e+00	989.00
IUUC-Xtr-132857	Xenopus tropicalis	47.84	0.00e+00	1146.00
IUUC-Xma-133138	Xiphophorus maculatus	48.22	0.00e+00	1190.00
IUUC-Yli-134399	Yarrowia lipolytica	60.90	0.00e+00	1083.00
IUUC-Zma-135612	Zea mays	46.66	0.00e+00	1116.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence