iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115528

Ensembl Protein ID

ENSSSCP00000026101.1

UniProt Accession

I3LPS4; I3LPS4_PIG

Protein Name

Tyrosine-protein kinase

Gene Name

LOC100627269

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000020923.1	ENSSSCT00000022403.1	ENSSSCP00000026101.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-14	53.0	56	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ v +ly+y+a nd +L++ kG++++++   ++ ++W+ +++ ++g++G +P+nFv+++e
   Q: 56   EHFVVALYNYNAMNDRDLQMLKGEKLQIL---KEAGDWWLAKSLTTGREGYVPSNFVARVE 113
           57799************************...88899**********************97 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MGVVSSKRQV KEKGKDGWSP VKASTYSKEP PPLPPLVVFN HLAPPPPNTT HPDQEEHFVV 60
ALYNYNAMND RDLQMLKGEK LQILKEAGDW WLAKSLTTGR EGYVPSNFVA RVETLEVEKW 120

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Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNG GCAGGGGGAT 60
CTGAAGAGCT ATGGTGAGAG GCCACTGAAT ACTGCCAAGG TAAGTCGCGT CTGCCGCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

ssc:100627269

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dno-029643	Dasypus novemcinctus	73.85	2.00e-129	454.00
IUUC-Ete-032602	Echinops telfairi	76.33	3.00e-100	358.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence