iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044449

UUCD1 version

UUC-GoG-00288

Ensembl Protein ID

ENSGGOP00000006862.2

UniProt Accession

G3QVT0; G3QVT0_GORGO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000007009.2	ENSGGOT00000007043.2	ENSGGOP00000006862.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.30e-130	434.4	76	408

Active Site

Position(s)	Description	Evidence
377	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl krl+++f+gEegld+gGv+re+l+lls+e+ np++glf+ys +d +tlq+npds + npehl++F+f+Gr++g+a+++g+++d 
   Q: 76   PKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAV-NPEHLSYFHFVGRIMGMAVFHGHYIDG 163
           678999*****************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+d+e vdp+l++sl +i+en   di+   ld tf+v+++ +ge+ ++eLkp+G++ipV++eNk+eYv+l+v+
   Q: 164  GFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEN---DITGV-LDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVN 248
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfnevip++ll+ F+e+elel+icG  +idv+d+k +t+ k+ +t+ds+ ++wFw+++e f++e r+++LqFv
   Q: 249  WRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKH-CTPDSNIVKWFWKAVEFFDEERRARLLQFV 336
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgssr+Pl+Gf++l+    prlf+i++ da +++lP+++TCfn++++P+Y+s+e+l+ekLl+Aieet gF +
   Q: 337  TGSSRVPLQGFKALQgaagPRLFTIHQiDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAV 408
           **********************************************************************76 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

RQNQLKDQQQ QQVVSLCPDD TECLTVPRYK RDLVQKLKIL RQELSQQQPQ AGHCRIEVSR 60
EEIFEESYRQ VMKMRPKDLW KRLMIKFRGE EGLDYGGVAR EWLYLLSHEM LNPYYGLFQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCAGAACC AATTGAAAGA CCAACAGCAA CAGCAAGTGG TATCGTTATG TCCTGATGAC 60
ACAGAATGCC TGACAGTCCC AAGGTACAAG CGAGACCTGG TTCAGAAACT AAAAATTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-007472	Arabidopsis thaliana	45.10	3.00e-90	328.00
IUUC-Csa-024063	Chlorocebus sabaeus	99.75	0.00e+00	826.00
IUUC-Cho-024804	Choloepus hoffmanni	99.35	0.00e+00	646.00
IUUC-Dme-031740	Drosophila melanogaster	71.91	5.00e-172	598.00
IUUC-Fca-036047	Felis catus	99.24	0.00e+00	825.00
IUUC-Itr-048042	Ictidomys tridecemlineatus	99.24	0.00e+00	826.00
IUUC-Olu-087813	Ostreococcus lucimarinus	41.95	5.00e-85	307.00
IUUC-Pop-099520	Populus trichocarpa	45.32	2.00e-91	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence