iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000015117.2	ENSCJAT00000029484.2	ENSCJAP00000027903.2
ENSCJAG00000015117.2	ENSCJAT00000029519.2	ENSCJAP00000027934.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.50e-24	85.0	403	475
E3 adaptor/Cullin RING/DCX/DWD	3.70e-38	128.8	11	43
UBD/Beta-Prp	8.30e-52	177.2	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           e+p+ef+CpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e ++
   Q: 403  EIPDEFICPITRELMKDPVIASDGYSYEKEAMENWISTKKRTSPMTNLVLPSVVLTPNRTLKMAINRWLELHQ 475
           69*******************************************************************9876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+af  s  ll+++s D+t+++++l++++
   Q: 11   HGDDVNCCAFsfS--LLATCSLDKTVRLYSLSDFT 43
           9*********644..9**************98876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  + sllat s d+t++++++++ +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SFSLLATCSLDKTVRLYSLSDFTElpHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQTLAVM 92
           566666655.55889..9*******************9666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  l+sG +d t+ +w+ ++++ ++ + s++dg+    +++p+g+ +v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYR-CGSVKDGSLVACAFSPNGSFFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           9765267*********************************9.*********************************98.5678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d +vk+w ++
   Q: 179  HDLGITCCDFSSQPvsdgeqglqfFRLASCGQDCQVKIWVVS 220
           *********9998899999********************765 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SFSLLATCSL DKTVRLYSLS DFTELPHSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTENGQTLA VMEQPSGSPV RVCQFSPDST CLASGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTGTAAG TGAGAGCGGC CGTGCCCACG GGTCGGCTCA GCAGTGGCGG CGATAGGTGG 60
GGGAGCGACT GGGCTCTGCC GAAGGAGCCT CCTCGCGTGA GGCGTTTGAA CCCTCCGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cjc:100404528

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	93.07	0.00e+00	928.00
IUUC-Apl-003529	Anas platyrhynchos	75.63	0.00e+00	758.00
IUUC-Aca-004257	Anolis carolinensis	70.43	0.00e+00	693.00
IUUC-Ame-011357	Astyanax mexicanus	51.77	4.00e-116	411.00
IUUC-Bta-013032	Bos taurus	87.63	0.00e+00	874.00
IUUC-Cfa-021197	Canis familiaris	90.97	0.00e+00	914.00
IUUC-Cpo-022279	Cavia porcellus	90.13	0.00e+00	902.00
IUUC-Csa-023954	Chlorocebus sabaeus	95.59	0.00e+00	943.00
IUUC-Cho-025083	Choloepus hoffmanni	74.07	2.00e-158	551.00
IUUC-Cin-025786	Ciona intestinalis	34.14	6.00e-77	281.00
IUUC-Dre-028087	Danio rerio	56.17	5.00e-142	497.00
IUUC-Dno-028919	Dasypus novemcinctus	92.65	0.00e+00	922.00
IUUC-Dor-031112	Dipodomys ordii	88.87	0.00e+00	883.00
IUUC-Ete-032405	Echinops telfairi	88.63	0.00e+00	639.00
IUUC-Eca-033254	Equus caballus	90.13	0.00e+00	895.00
IUUC-Eeu-034545	Erinaceus europaeus	85.71	0.00e+00	824.00
IUUC-Fca-035482	Felis catus	92.65	0.00e+00	921.00
IUUC-Fal-036976	Ficedula albicollis	62.11	8.00e-165	573.00
IUUC-Gmo-039213	Gadus morhua	54.41	2.00e-135	475.00
IUUC-Gga-040561	Gallus gallus	73.58	0.00e+00	742.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.98	9.00e-141	493.00
IUUC-Ggo-045503	Gorilla gorilla	95.80	0.00e+00	948.00
IUUC-Hsa-045910	Homo sapiens	95.80	0.00e+00	948.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	90.72	0.00e+00	713.00
IUUC-Loc-052307	Lepisosteus oculatus	58.93	1.00e-165	575.00
IUUC-Laf-053587	Loxodonta africana	91.18	0.00e+00	910.00
IUUC-Mcc-055679	Macaca mulatta	95.59	0.00e+00	947.00
IUUC-Meu-055962	Macropus eugenii	71.22	0.00e+00	652.00
IUUC-Mga-059652	Meleagris gallopavo	73.38	0.00e+00	748.00
IUUC-Mmr-060943	Microcebus murinus	90.38	0.00e+00	895.00
IUUC-Mdo-062592	Monodelphis domestica	82.05	0.00e+00	822.00
IUUC-Mmu-063577	Mus musculus	81.72	0.00e+00	818.00
IUUC-Mpu-066422	Mustela putorius furo	91.39	0.00e+00	911.00
IUUC-Mlu-067250	Myotis lucifugus	90.34	0.00e+00	897.00
IUUC-Nle-069517	Nomascus leucogenys	95.59	0.00e+00	946.00
IUUC-Opr-070776	Ochotona princeps	89.71	0.00e+00	881.00
IUUC-Ont-071821	Oreochromis niloticus	57.32	5.00e-150	524.00
IUUC-Oan-073706	Ornithorhynchus anatinus	82.11	0.00e+00	825.00
IUUC-Ocu-074766	Oryctolagus cuniculus	83.33	0.00e+00	803.00
IUUC-Ola-086531	Oryzias latipes	57.26	1.00e-146	512.00
IUUC-Oga-088388	Otolemur garnettii	90.55	0.00e+00	901.00
IUUC-Oar-089748	Ovis aries	87.84	0.00e+00	874.00
IUUC-Ptr-090616	Pan troglodytes	95.56	0.00e+00	939.00
IUUC-Pan-091769	Papio anubis	94.77	0.00e+00	674.00
IUUC-Psi-093334	Pelodiscus sinensis	77.73	0.00e+00	731.00
IUUC-Pma-094383	Petromyzon marinus	49.12	1.00e-133	469.00
IUUC-Pfo-096832	Poecilia formosa	53.01	2.00e-139	489.00
IUUC-Pab-098139	Pongo abelii	94.59	0.00e+00	759.00
IUUC-Pca-100523	Procavia capensis	76.26	0.00e+00	738.00
IUUC-Pva-102286	Pteropus vampyrus	89.92	0.00e+00	873.00
IUUC-Rno-104831	Rattus norvegicus	83.82	0.00e+00	838.00
IUUC-Sha-107499	Sarcophilus harrisii	83.19	0.00e+00	832.00
IUUC-Sar-113389	Sorex araneus	86.76	0.00e+00	840.00
IUUC-Tgu-116769	Taeniopygia guttata	72.48	0.00e+00	726.00
IUUC-Tru-118774	Takifugu rubripes	53.69	6.00e-139	487.00
IUUC-Tsy-119595	Tarsius syrichta	80.83	0.00e+00	648.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.78	5.00e-147	514.00
IUUC-Tbe-127938	Tupaia belangeri	82.30	2.00e-146	511.00
IUUC-Ttr-128193	Tursiops truncatus	90.57	0.00e+00	771.00
IUUC-Vpa-130275	Vicugna pacos	91.60	0.00e+00	910.00
IUUC-Xtr-131982	Xenopus tropicalis	61.65	5.00e-169	587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence