iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090373

Ensembl Protein ID

ENSOARP00000012951.1

UniProt Accession

W5PR73; W5PR73_SHEEP

Genbank Protein ID

ENSOARP00000012951

Protein Name

Coronin

Genbank Nucleotide ID

AMGL01061982

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012083.1	ENSOART00000013140.1	ENSOARP00000012951.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-12	47.3	107	139

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 107  GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 139
           8***********977799*************75 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

GGKGPCWRLR PTKKLGLHWL GTSHLPHIMF RKVVRQSKFR HVFGQPVKND QCYEDIRVSR 60
VTWDSTFCAV NPKFLAVIVE ASGGGAFLVL PLSKTGRIDK AYPTVCGHTG PVLDIDWCPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGAAAG GGCCCTGCTG GCGACTGAGA CCCACCAAGA AGCTAGGCTT GCACTGGCTG 60
GGCACCTCCC ACCTCCCTCA CACATACCAG AGCCTGGGAG AGGCCCCCCA AACCCCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012984	Bos taurus	80.57	0.00e+00	785.00
IUUC-Pca-100411	Procavia capensis	92.29	0.00e+00	703.00
IUUC-Sha-106609	Sarcophilus harrisii	90.58	0.00e+00	691.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence