iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117329

Ensembl Protein ID

ENSTGUP00000006371.1

UniProt Accession

H0Z722; H0Z722_TAEGU

Genbank Protein ID

ENSTGUP00000006371

Protein Name

Coronin

Genbank Nucleotide ID

ABQF01001542

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006149.1	ENSTGUT00000006435.1	ENSTGUP00000006371.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-17	62.2	80	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d+ ++sGs D+t++vW +
   Q: 80   GHTGPVLDIDWcphNDHVIASGSEDCTVMVWQI 112
           8***********977799*************85 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KTDQCYDDIR VSRVTWDSTF CAVNPSFVAI IVEASGGGAF 60
LVLPLHKTGR IDKSYPTVCG HTGPVLDIDW CPHNDHVIAS GSEDCTVMVW QIPENGLSQP 120

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Nucleotide Sequence
(Fasta)

ATGTCCTTCC GGAAGGTGGT GCGGCAGAGC AAATTCCGGC ACGTGTTCGG GCAGCCGGTG 60
AAGACGGACC AGTGCTACGA TGACATCCGC GTGTCCCGCG TCACCTGGGA CAGCACCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gga-041140	Gallus gallus	91.83	0.00e+00	681.00
IUUC-Oar-090373	Ovis aries	88.37	0.00e+00	672.00
IUUC-Pca-100411	Procavia capensis	90.14	0.00e+00	686.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence