iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092198

Ensembl Protein ID

ENSPANP00000014054.1

UniProt Accession

A0A096NM45; A0A096NM45_PAPAN

Genbank Protein ID

ENSPANP00000014054

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01075513

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000017450.1	ENSPANT00000018929.1	ENSPANP00000014054.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.00e-43	142.6	190	230
UBD/Beta-Prp	8.00e-55	186.2	143	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 190  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 230
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
            +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++ 
   Q: 143  KKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ- 230
           4677889999*********99***************************************9778************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l 
   Q: 231  AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF 319
           ********************************************5333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriW 249
           gh++ v+ +r+sp+++ + sgs D ++r+W
   Q: 320  GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 349
           ****************************** PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MGLPPCAEPV SVLCQPKAQN LVLSKGTDYG LVLPVHQVAE RVEALGQFVM KTRRTLKGHG 60
NKVLCMDWCK DKRRIVSSSQ DGKVIVWDSF TTNKEHAVTM PCTWVMACAY APSGCAIACG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCTGC CTCCCTGTGC GGAGCCTGTG TCTGTGCTGT GCCAGCCCAA AGCCCAGAAC 60
CTGGTCCTTA GCAAGGGGAC TGACTATGGC CTTGTCCTTC CAGTGCACCA GGTGGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	99.37	0.00e+00	661.00
IUUC-Apl-003399	Anas platyrhynchos	99.04	0.00e+00	648.00
IUUC-Aca-004861	Anolis carolinensis	96.86	0.00e+00	654.00
IUUC-Ame-011851	Astyanax mexicanus	94.30	0.00e+00	636.00
IUUC-Bta-012438	Bos taurus	98.74	0.00e+00	660.00
IUUC-Cel-018408	Caenorhabditis elegans	66.35	1.00e-131	462.00
IUUC-Cja-019086	Callithrix jacchus	99.05	0.00e+00	657.00
IUUC-Cfa-021255	Canis familiaris	99.05	0.00e+00	654.00
IUUC-Cpo-021398	Cavia porcellus	97.81	0.00e+00	649.00
IUUC-Csa-023776	Chlorocebus sabaeus	99.06	0.00e+00	661.00
IUUC-Cin-025305	Ciona intestinalis	61.30	5.00e-123	433.00
IUUC-Csv-026058	Ciona savignyi	61.95	1.00e-122	432.00
IUUC-Dre-028572	Danio rerio	93.08	0.00e+00	634.00
IUUC-Dno-029958	Dasypus novemcinctus	87.78	3.00e-112	397.00
IUUC-Dor-031013	Dipodomys ordii	99.22	2.00e-152	531.00
IUUC-Dme-031889	Drosophila melanogaster	68.79	2.00e-137	481.00
IUUC-Eca-033977	Equus caballus	99.68	0.00e+00	659.00
IUUC-Eeu-035079	Erinaceus europaeus	98.74	0.00e+00	659.00
IUUC-Fca-035693	Felis catus	95.83	0.00e+00	664.00
IUUC-Fal-037345	Ficedula albicollis	97.48	0.00e+00	655.00
IUUC-Gmo-039222	Gadus morhua	93.08	0.00e+00	633.00
IUUC-Gga-040320	Gallus gallus	97.80	0.00e+00	657.00
IUUC-Gac-042644	Gasterosteus aculeatus	93.40	0.00e+00	636.00
IUUC-Ggo-044489	Gorilla gorilla	99.05	0.00e+00	659.00
IUUC-Hsa-046434	Homo sapiens	99.06	0.00e+00	660.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	94.30	4.00e-177	613.00
IUUC-Loc-052790	Lepisosteus oculatus	95.87	0.00e+00	640.00
IUUC-Laf-054255	Loxodonta africana	97.78	0.00e+00	647.00
IUUC-Mcc-055610	Macaca mulatta	99.05	0.00e+00	656.00
IUUC-Meu-056819	Macropus eugenii	96.79	4.00e-180	623.00
IUUC-Mga-059740	Meleagris gallopavo	97.81	0.00e+00	657.00
IUUC-Mmr-061221	Microcebus murinus	98.74	0.00e+00	660.00
IUUC-Mdo-062619	Monodelphis domestica	98.43	0.00e+00	660.00
IUUC-Mmu-064266	Mus musculus	98.74	0.00e+00	660.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	1.00e-180	625.00
IUUC-Mlu-067221	Myotis lucifugus	96.88	0.00e+00	649.00
IUUC-Nle-069515	Nomascus leucogenys	98.86	0.00e+00	720.00
IUUC-Opr-070195	Ochotona princeps	88.36	4.00e-165	573.00
IUUC-Ont-071535	Oreochromis niloticus	83.65	1.00e-155	542.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	8.00e-107	378.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	626.00
IUUC-Ola-086578	Oryzias latipes	94.01	0.00e+00	634.00
IUUC-Oga-089090	Otolemur garnettii	98.44	0.00e+00	655.00
IUUC-Oar-090017	Ovis aries	99.05	0.00e+00	652.00
IUUC-Ptr-091280	Pan troglodytes	99.68	0.00e+00	658.00
IUUC-Psi-093030	Pelodiscus sinensis	97.48	0.00e+00	655.00
IUUC-Pfo-097182	Poecilia formosa	93.71	0.00e+00	637.00
IUUC-Pab-098157	Pongo abelii	99.68	0.00e+00	661.00
IUUC-Pca-100988	Procavia capensis	72.64	3.00e-125	441.00
IUUC-Pva-102232	Pteropus vampyrus	100.00	7.00e-161	559.00
IUUC-Rno-105526	Rattus norvegicus	94.69	1.00e-179	622.00
IUUC-Sha-106754	Sarcophilus harrisii	98.43	0.00e+00	656.00
IUUC-Ssc-115390	Sus scrofa	98.43	0.00e+00	655.00
IUUC-Tgu-117377	Taeniopygia guttata	95.43	0.00e+00	651.00
IUUC-Tru-117938	Takifugu rubripes	93.71	0.00e+00	635.00
IUUC-Tsy-119392	Tarsius syrichta	85.22	1.00e-154	539.00
IUUC-Tni-119834	Tetraodon nigroviridis	76.73	9.00e-148	516.00
IUUC-Tbe-127469	Tupaia belangeri	96.54	0.00e+00	627.00
IUUC-Ttr-128252	Tursiops truncatus	98.11	0.00e+00	649.00
IUUC-Vpa-130173	Vicugna pacos	91.41	3.00e-137	481.00
IUUC-Xtr-131803	Xenopus tropicalis	96.54	0.00e+00	650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence