iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004419

UUCD1 version

UUC-AnC-00521

Ensembl Protein ID

ENSACAP00000003988.2

UniProt Accession

G1KCI2; G1KCI2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004085.3	ENSACAT00000004080.3	ENSACAP00000003988.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-07	31.7	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTipGLIASGCLDGEVRIWDLH 126
           6777779*****66679***************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGT QALGAQRLLQ ELVEDKTRWM KWEGKKVELP DSPRSTFLLA 60
FSPDRTLMAS THVNHNIYIT EVKTGKCVHS LVGHRRTPWC VTFHPTIPGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCCATGA AGGCAGTCTT GCAAGGTGTA GATGGCCCTT CTGTAGGTTC TTGGGGCTTT 60
TGATCTGGTG TCTGTTGGTG ACTCATTCCC CTGCATTGCT GCAGTAAAAG CCATGAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	78.25	0.00e+00	1413.00
IUUC-Atr-002557	Amborella trichopoda	37.26	2.00e-30	127.00
IUUC-Apl-004186	Anas platyrhynchos	86.84	0.00e+00	1417.00
IUUC-Aly-006308	Arabidopsis lyrata	37.16	3.00e-28	119.00
IUUC-Ath-007656	Arabidopsis thaliana	35.98	6.00e-28	119.00
IUUC-Ame-011354	Astyanax mexicanus	59.22	0.00e+00	881.00
IUUC-Bta-012455	Bos taurus	77.48	0.00e+00	1804.00
IUUC-Bdi-014580	Brachypodium distachyon	41.10	1.00e-29	124.00
IUUC-Bol-016094	Brassica oleracea	39.13	2.00e-28	120.00
IUUC-Bra-017308	Brassica rapa	37.74	3.00e-29	123.00
IUUC-Cja-019073	Callithrix jacchus	93.00	2.00e-146	512.00
IUUC-Cfa-020994	Canis familiaris	80.72	0.00e+00	1222.00
IUUC-Cpo-022101	Cavia porcellus	79.13	0.00e+00	1756.00
IUUC-Csa-023273	Chlorocebus sabaeus	78.40	0.00e+00	1288.00
IUUC-Cin-025567	Ciona intestinalis	53.40	7.00e-57	214.00
IUUC-Csv-026005	Ciona savignyi	48.03	3.00e-57	214.00
IUUC-Dre-028282	Danio rerio	61.07	0.00e+00	850.00
IUUC-Dno-029948	Dasypus novemcinctus	77.47	0.00e+00	1751.00
IUUC-Dor-030568	Dipodomys ordii	71.35	0.00e+00	874.00
IUUC-Ete-032864	Echinops telfairi	70.73	0.00e+00	860.00
IUUC-Eca-034392	Equus caballus	77.87	0.00e+00	1285.00
IUUC-Eeu-034440	Erinaceus europaeus	65.06	0.00e+00	884.00
IUUC-Fca-035359	Felis catus	75.00	0.00e+00	1717.00
IUUC-Fal-037483	Ficedula albicollis	84.92	0.00e+00	1441.00
IUUC-Gmo-039343	Gadus morhua	75.58	0.00e+00	790.00
IUUC-Gga-040787	Gallus gallus	83.74	0.00e+00	644.00
IUUC-Gac-041321	Gasterosteus aculeatus	65.48	0.00e+00	934.00
IUUC-Gma-044022	Glycine max	37.13	2.00e-30	127.00
IUUC-Ggo-044775	Gorilla gorilla	83.69	0.00e+00	956.00
IUUC-Hsa-045708	Homo sapiens	76.61	0.00e+00	1788.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	9.00e-31	128.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	70.41	0.00e+00	873.00
IUUC-Lch-050255	Latimeria chalumnae	77.26	0.00e+00	1061.00
IUUC-Lpe-050684	Leersia perrieri	41.18	2.00e-31	130.00
IUUC-Loc-052881	Lepisosteus oculatus	68.04	0.00e+00	998.00
IUUC-Laf-053342	Loxodonta africana	77.34	2.00e-170	592.00
IUUC-Mcc-055848	Macaca mulatta	75.19	0.00e+00	1761.00
IUUC-Meu-056320	Macropus eugenii	71.66	0.00e+00	872.00
IUUC-Mtr-058484	Medicago truncatula	39.04	1.00e-29	125.00
IUUC-Mga-059401	Meleagris gallopavo	90.95	0.00e+00	1087.00
IUUC-Mmr-061037	Microcebus murinus	78.15	0.00e+00	1736.00
IUUC-Mdo-062484	Monodelphis domestica	67.68	0.00e+00	1010.00
IUUC-Mmu-064090	Mus musculus	76.27	0.00e+00	1756.00
IUUC-Mac-065308	Musa acuminata	40.32	1.00e-29	125.00
IUUC-Mpu-066165	Mustela putorius furo	78.88	0.00e+00	1239.00
IUUC-Mlu-068038	Myotis lucifugus	76.42	0.00e+00	1773.00
IUUC-Nle-069361	Nomascus leucogenys	79.73	0.00e+00	1580.00
IUUC-Opr-070360	Ochotona princeps	82.23	0.00e+00	792.00
IUUC-Ont-071277	Oreochromis niloticus	67.76	0.00e+00	936.00
IUUC-Oan-073623	Ornithorhynchus anatinus	79.03	0.00e+00	933.00
IUUC-Ocu-074600	Oryctolagus cuniculus	85.41	0.00e+00	1169.00
IUUC-Oba-075024	Oryza barthii	37.07	5.00e-33	136.00
IUUC-Obr-076172	Oryza brachyantha	37.07	2.00e-33	137.00
IUUC-Ogl-077411	Oryza glaberrima	37.07	6.00e-33	135.00
IUUC-Ogu-078025	Oryza glumaepatula	37.07	9.00e-33	135.00
IUUC-Oni-082463	Oryza nivara	37.07	7.00e-33	136.00
IUUC-Opu-084041	Oryza punctata	37.07	9.00e-33	135.00
IUUC-Oru-085075	Oryza rufipogon	37.07	2.00e-32	134.00
IUUC-Osa-085781	Oryza sativa	37.07	5.00e-33	135.00
IUUC-Ola-086729	Oryzias latipes	65.45	0.00e+00	920.00
IUUC-Olu-087735	Ostreococcus lucimarinus	38.71	2.00e-23	103.00
IUUC-Oga-089113	Otolemur garnettii	75.95	0.00e+00	1689.00
IUUC-Oar-090171	Ovis aries	79.54	0.00e+00	1723.00
IUUC-Ptr-090970	Pan troglodytes	76.68	0.00e+00	1790.00
IUUC-Pan-092778	Papio anubis	78.71	0.00e+00	1295.00
IUUC-Psi-093571	Pelodiscus sinensis	86.03	0.00e+00	1439.00
IUUC-Pma-094563	Petromyzon marinus	75.10	7.00e-106	376.00
IUUC-Ppa-095832	Physcomitrella patens	37.68	7.00e-30	125.00
IUUC-Pfo-097365	Poecilia formosa	65.47	0.00e+00	850.00
IUUC-Pab-098647	Pongo abelii	71.17	0.00e+00	884.00
IUUC-Pop-099742	Populus trichocarpa	40.86	6.00e-31	129.00
IUUC-Pca-101035	Procavia capensis	68.90	0.00e+00	830.00
IUUC-Ppe-101783	Prunus persica	42.22	2.00e-30	127.00
IUUC-Pva-103187	Pteropus vampyrus	98.25	0.00e+00	704.00
IUUC-Rno-105701	Rattus norvegicus	76.19	0.00e+00	1743.00
IUUC-Sha-107612	Sarcophilus harrisii	75.55	0.00e+00	1780.00
IUUC-Smo-109107	Selaginella moellendorffii	41.25	1.00e-27	118.00
IUUC-Sit-110786	Setaria italica	41.10	2.00e-31	130.00
IUUC-Sly-111631	Solanum lycopersicum	34.59	1.00e-31	131.00
IUUC-Stu-112031	Solanum tuberosum	37.62	2.00e-31	130.00
IUUC-Sar-113242	Sorex araneus	71.22	0.00e+00	769.00
IUUC-Ssc-116094	Sus scrofa	77.20	0.00e+00	1776.00
IUUC-Tru-118308	Takifugu rubripes	63.49	0.00e+00	862.00
IUUC-Tsy-119552	Tarsius syrichta	69.81	0.00e+00	855.00
IUUC-Tca-121616	Theobroma cacao	37.62	3.00e-31	130.00
IUUC-Tae-124768	Triticum aestivum	40.96	1.00e-29	124.00
IUUC-Tur-126480	Triticum urartu	40.96	5.00e-30	125.00
IUUC-Tbe-127902	Tupaia belangeri	68.33	0.00e+00	665.00
IUUC-Ttr-129278	Tursiops truncatus	69.54	0.00e+00	827.00
IUUC-Vpa-130741	Vicugna pacos	77.69	0.00e+00	743.00
IUUC-Vvi-131437	Vitis vinifera	45.45	4.00e-30	126.00
IUUC-Xtr-132247	Xenopus tropicalis	58.33	0.00e+00	780.00
IUUC-Xma-134277	Xiphophorus maculatus	65.98	0.00e+00	937.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence