iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010899.3	ENSOCUT00000009552.3	ENSOCUP00000008234.3
ENSOCUG00000010899.3	ENSOCUT00000010899.3	ENSOCUP00000009377.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.54	0.00e+00	790.00	IUUC-Hsa-046376
E3 activity/RING/RING	79.36	0.00e+00	650.00	IUUC-Mmu-063207
E3 activity/RING/RING	81.95	0.00e+00	667.00	IUUC-Rno-105641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MASLADRVRD HGRIAAGLLF NLLVSICIVF LNKWIYVHHG FPNMSLTLVH FVVTWLGLYI 60
CQKLDIFAPK SLPPSKLLLL ALSFCGFVVF TNLSLQTNTI GTYQLAKAMT TPVIIAIQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTGGTCAC GCGCGGAGAG GGGCGGGGCG CGAGACGTGC TGCCGCGTCC TCGGCGGGTC 60
TGAGGGCGGT GGCGGAGCAT GAGTTTGCCG CCGAGGCTGG TGCTCGCTGG AGATCCGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR004853--Sugar_P_trans_dom
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF03151--TPT
PF00641--zf-RanBP

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002039	Ailuropoda melanoleuca	92.91	0.00e+00	800.00
IUUC-Apl-003193	Anas platyrhynchos	65.05	3.00e-158	551.00
IUUC-Aca-004305	Anolis carolinensis	56.30	2.00e-116	412.00
IUUC-Ame-010675	Astyanax mexicanus	45.26	3.00e-83	302.00
IUUC-Bta-013270	Bos taurus	91.68	0.00e+00	757.00
IUUC-Cja-019744	Callithrix jacchus	91.87	0.00e+00	779.00
IUUC-Cfa-020807	Canis familiaris	90.79	0.00e+00	738.00
IUUC-Cpo-022182	Cavia porcellus	89.47	0.00e+00	753.00
IUUC-Cre-022828	Chlamydomonas reinhardtii	35.42	8.00e-06	41.20
IUUC-Csa-023541	Chlorocebus sabaeus	93.50	0.00e+00	773.00
IUUC-Cho-024831	Choloepus hoffmanni	99.10	8.00e-55	206.00
IUUC-Csv-026151	Ciona savignyi	31.17	9.00e-11	60.50
IUUC-Dre-028419	Danio rerio	42.01	6.00e-49	188.00
IUUC-Dno-028950	Dasypus novemcinctus	90.60	0.00e+00	789.00
IUUC-Dor-031048	Dipodomys ordii	75.65	8.00e-103	367.00
IUUC-Ete-032264	Echinops telfairi	73.51	5.00e-110	390.00
IUUC-Eca-033301	Equus caballus	81.78	0.00e+00	690.00
IUUC-Eeu-035005	Erinaceus europaeus	78.86	0.00e+00	634.00
IUUC-Fca-035454	Felis catus	92.48	0.00e+00	786.00
IUUC-Fal-036720	Ficedula albicollis	60.60	4.00e-71	261.00
IUUC-Gmo-039296	Gadus morhua	42.07	3.00e-46	178.00
IUUC-Gga-040251	Gallus gallus	64.30	2.00e-153	535.00
IUUC-Gac-041528	Gasterosteus aculeatus	39.59	1.00e-33	137.00
IUUC-Ggo-044948	Gorilla gorilla	85.77	0.00e+00	706.00
IUUC-Hsa-046376	Homo sapiens	93.54	0.00e+00	780.00
IUUC-Itr-048328	Ictidomys tridecemlineatus	92.51	0.00e+00	768.00
IUUC-Lch-050037	Latimeria chalumnae	57.61	5.00e-119	421.00
IUUC-Lpe-051590	Leersia perrieri	29.29	3.00e-24	107.00
IUUC-Loc-051837	Lepisosteus oculatus	50.20	2.00e-114	405.00
IUUC-Laf-053483	Loxodonta africana	84.82	0.00e+00	717.00
IUUC-Mcc-055294	Macaca mulatta	93.54	0.00e+00	780.00
IUUC-Mga-060007	Meleagris gallopavo	64.10	7.00e-144	503.00
IUUC-Mmr-060673	Microcebus murinus	92.48	0.00e+00	793.00
IUUC-Mdo-063057	Monodelphis domestica	71.46	0.00e+00	647.00
IUUC-Mmu-063207	Mus musculus	77.96	2.00e-179	622.00
IUUC-Mpu-065836	Mustela putorius furo	91.26	0.00e+00	794.00
IUUC-Mlu-068193	Myotis lucifugus	87.40	0.00e+00	781.00
IUUC-Nle-069927	Nomascus leucogenys	93.54	0.00e+00	780.00
IUUC-Opr-070590	Ochotona princeps	87.85	0.00e+00	725.00
IUUC-Ont-071984	Oreochromis niloticus	42.49	6.00e-51	194.00
IUUC-Oan-072744	Ornithorhynchus anatinus	71.46	3.00e-163	567.00
IUUC-Olo-081087	Oryza longistaminata	29.29	4.00e-24	107.00
IUUC-Opu-084017	Oryza punctata	29.29	3.00e-24	107.00
IUUC-Ola-087329	Oryzias latipes	41.19	2.00e-50	192.00
IUUC-Oga-088135	Otolemur garnettii	83.84	0.00e+00	727.00
IUUC-Oar-089726	Ovis aries	91.70	0.00e+00	803.00
IUUC-Ptr-091399	Pan troglodytes	93.74	0.00e+00	782.00
IUUC-Pan-092720	Papio anubis	93.54	0.00e+00	780.00
IUUC-Psi-093591	Pelodiscus sinensis	63.83	7.00e-128	450.00
IUUC-Pma-094500	Petromyzon marinus	33.64	2.00e-27	115.00
IUUC-Pfo-096316	Poecilia formosa	39.80	7.00e-72	264.00
IUUC-Pab-097696	Pongo abelii	93.33	0.00e+00	771.00
IUUC-Pca-100974	Procavia capensis	83.13	0.00e+00	738.00
IUUC-Pva-102488	Pteropus vampyrus	85.31	0.00e+00	686.00
IUUC-Rno-105641	Rattus norvegicus	81.95	0.00e+00	656.00
IUUC-Sha-107314	Sarcophilus harrisii	72.53	0.00e+00	664.00
IUUC-Sar-112938	Sorex araneus	84.35	0.00e+00	722.00
IUUC-Ssc-115495	Sus scrofa	91.87	0.00e+00	766.00
IUUC-Tgu-116623	Taeniopygia guttata	63.50	2.00e-149	522.00
IUUC-Tru-117820	Takifugu rubripes	39.76	4.00e-47	182.00
IUUC-Tsy-119162	Tarsius syrichta	64.50	3.00e-81	295.00
IUUC-Tni-119793	Tetraodon nigroviridis	42.35	1.00e-43	170.00
IUUC-Tbe-127816	Tupaia belangeri	89.38	1.00e-120	426.00
IUUC-Ttr-129194	Tursiops truncatus	80.35	2.00e-177	615.00
IUUC-Vpa-130326	Vicugna pacos	85.45	0.00e+00	700.00
IUUC-Xtr-132216	Xenopus tropicalis	55.34	1.00e-116	413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence