iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074015

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02048920

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015515.3	ENSOCUT00000015537.3	ENSOCUP00000013351.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-56	185.6	105	142
UBD/Beta-Prp	1.00e-116	389.4	56	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvl 35
           Ht ++ claf  d  +lvs + D  +t+ vWD+++g+ 
   Q: 105  HTHGIACLAFdLDgQRLVSVGLDskNTVCVWDWKRGKM 142
           99*********66699*****9999********99976 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgs..rdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcv 87
           +++gh ++ i+ ++ +p++ l+atg   +   i vwd  t ++++ l   h+ +++++ f+ dg+ lv+++ D  +t++vwd + gk++
   Q: 56   FYRGHSDDIIS-LALHPERVLVATGQvgKEPYICVWDSYTVQTISVLkDVHTHGIACLAFDLDGQRLVSVGLDskNTVCVWDWKRGKML 143
           67889999999.9999********96115567***************777*************************************** PP
   S: 88   htlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkll 172
           +   gh+d++ ++s++ ++ +klvs + ++ i+ w l  +    +  ++ ++ ++ +++++ +    l  sG+l++ + +W+    +l+
   Q: 144  SMAPGHTDRIFDISWDLYQpNKLVSCG-VKHIKFWSLCGNALTPKrgVFGKTGDLQTILCLACARdELTYSGALNGDIYVWKG--INLI 229
           *****************8867777777.*********999999999955555555555555555559**************66..9*** PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           rt +g+ht  + s++  ++g  +++g++dg ++lwdl
   Q: 230  RTIQGAHTAGIFSMNACEEG--FATGGRDGCIRLWDL 264
           ***************99965..**************8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAARSAPSCH LRLEWVYGYR GHQCRNNLFY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGATTTCA TGACCTAAAC TCTGCTTTCA GCTTTGAGGT CAGCTACACA AATAAGAAAA 60
TGTGCACGTG GGAAGTCAGG TTTTGTTCCC CACCCAGTGT GTGGGCCAGA CGGCCCCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Eeu-035180	Erinaceus europaeus	78.82	0.00e+00	1462.00
IUUC-Pca-100107	Procavia capensis	75.08	0.00e+00	1400.00
IUUC-Sar-113401	Sorex araneus	85.69	0.00e+00	1223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence