iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067586

Ensembl Protein ID

ENSMLUP00000005816.2

UniProt Accession

L7N1B1; L7N1B1_MYOLU

Genbank Protein ID

ENSMLUP00000005816

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAPE02061771

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006358.2	ENSMLUT00000006366.2	ENSMLUP00000005816.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-08	35.2	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C +++ +e  +v C++  C  ewfH+ C++l+     p+ + w+CpkCr 
   Q: 211  TYC-LCNRASYGE--MVACDHdgCPmEWFHFSCVGLN---HAPKGK-WYCPKCRG 258
           69*.*******99..*********99***********...999997.******85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MLSPANREQI HLVNYVEDYL DSIESLPLDL QRNVSLMREM DSKYQEILKE LDEYDEKFKR 60
ETDSNRKRRA LHCLQRALIR SQELGDEKMQ IVRQMVELVE NRTRQVDRHV GLFEAHLEVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGCC CTGCCAACCG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGACTACCTG 60
GACTCCATCG AGTCCCTGCC TCTCGACCTG CAGAGAAACG TATCGCTGAT GCGGGAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	83.63	8.00e-118	416.00
IUUC-Apl-003910	Anas platyrhynchos	80.00	4.00e-111	394.00
IUUC-Aca-004874	Anolis carolinensis	78.72	1.00e-108	385.00
IUUC-Ame-011262	Astyanax mexicanus	60.62	3.00e-82	298.00
IUUC-Cja-018925	Callithrix jacchus	76.87	3.00e-106	377.00
IUUC-Cfa-020663	Canis familiaris	82.21	2.00e-115	408.00
IUUC-Csa-023825	Chlorocebus sabaeus	76.51	1.00e-105	375.00
IUUC-Dre-028562	Danio rerio	54.28	2.00e-68	252.00
IUUC-Dno-029834	Dasypus novemcinctus	82.56	2.00e-116	411.00
IUUC-Fca-035391	Felis catus	79.54	1.00e-101	362.00
IUUC-Fal-036838	Ficedula albicollis	79.00	2.00e-110	391.00
IUUC-Gga-040619	Gallus gallus	79.36	1.00e-110	392.00
IUUC-Gac-041996	Gasterosteus aculeatus	54.90	7.00e-78	283.00
IUUC-Lch-050397	Latimeria chalumnae	76.51	3.00e-107	380.00
IUUC-Loc-052038	Lepisosteus oculatus	69.77	1.00e-87	315.00
IUUC-Laf-054126	Loxodonta africana	81.85	2.00e-115	408.00
IUUC-Mdo-062452	Monodelphis domestica	81.85	4.00e-114	403.00
IUUC-Mmu-063412	Mus musculus	80.43	6.00e-113	400.00
IUUC-Nle-069122	Nomascus leucogenys	76.51	2.00e-105	375.00
IUUC-Ont-071606	Oreochromis niloticus	51.30	2.00e-73	268.00
IUUC-Oan-073023	Ornithorhynchus anatinus	78.29	3.00e-108	384.00
IUUC-Ola-086891	Oryzias latipes	56.03	2.00e-78	285.00
IUUC-Oga-087954	Otolemur garnettii	80.07	2.00e-112	397.00
IUUC-Oar-090006	Ovis aries	79.00	2.00e-109	388.00
IUUC-Ptr-090589	Pan troglodytes	76.87	3.00e-106	377.00
IUUC-Psi-093266	Pelodiscus sinensis	80.78	2.00e-112	398.00
IUUC-Pfo-097531	Poecilia formosa	52.90	5.00e-76	277.00
IUUC-Pab-098253	Pongo abelii	76.87	5.00e-106	377.00
IUUC-Pca-100278	Procavia capensis	52.45	2.00e-64	238.00
IUUC-Sha-107270	Sarcophilus harrisii	81.14	2.00e-112	398.00
IUUC-Ssc-115734	Sus scrofa	53.64	7.00e-60	223.00
IUUC-Tgu-116822	Taeniopygia guttata	79.36	9.00e-111	392.00
IUUC-Tru-118262	Takifugu rubripes	51.23	2.00e-64	239.00
IUUC-Tvi-122341	Trichoderma virens	51.39	1.00e-17	82.40
IUUC-Vpa-130063	Vicugna pacos	54.58	2.00e-60	225.00
IUUC-Xtr-132200	Xenopus tropicalis	72.95	4.00e-101	360.00
IUUC-Xma-133491	Xiphophorus maculatus	53.42	2.00e-77	282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence