iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101470

Ensembl Protein ID

EMJ18267

UniProt Accession

M5WWT6; M5WWT6_PRUPE

Genbank Protein ID

EMJ18267.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

KB639030

Gene Name

PRUPE_ppa001045mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa001045mg	EMJ18266	EMJ18266
PRUPE_ppa001045mg	EMJ18267	EMJ18267

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-35	118.9	184	224
UBD/Beta-Prp	1.70e-66	224.9	14	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           +++++++v+ +p +++++++ ++gt+ +w+++t+++ +s++  e +v++ kf+ ++++ v g++D++i+v++++t + v ++++h+d++++++++p+  ++
   Q: 14   RSERVKSVDLHPTEPWILASLYSGTVCIWNYQTQTMAKSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTLPYV 114
           5678999********************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklw 207
           +s s+d  i++wd+++g++  ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     ++++l++gs+d t k+w
   Q: 115  LSSSDDMLIKLWDWDKGWVCTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKPYLITGSDDHTAKVW 214
           ******************9999*********************************************98.*********6444555*************** PP
   S: 208  dlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvl 282
           d+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v+++ +++ +++v++ 
   Q: 215  DYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYMKSSRRVVIG 289
           ***************************************************************997777777643 PP

Organism

Prunus persica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQTQTMA KSFEVTELPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGACCAA AATCTCTCTC CCTCCCCTCC CTCTCTTCTT CTTCTTCTTC TCTCTCTGTG 60
CTCGGATCAC CTGGATCGCT AGGGTTTCTC TGACTGTGAT CTTGGCCGGA GCTCTGCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	73.44	0.00e+00	1407.00
IUUC-Aml-002154	Ailuropoda melanoleuca	62.67	0.00e+00	1117.00
IUUC-Atr-003090	Amborella trichopoda	80.42	0.00e+00	1534.00
IUUC-Apl-003976	Anas platyrhynchos	62.30	0.00e+00	1116.00
IUUC-Aca-004301	Anolis carolinensis	62.59	0.00e+00	1122.00
IUUC-Aly-006508	Arabidopsis lyrata	87.66	0.00e+00	1654.00
IUUC-Ath-007635	Arabidopsis thaliana	86.70	0.00e+00	1644.00
IUUC-Ago-007914	Ashbya gossypii	46.48	0.00e+00	716.00
IUUC-Acl-008237	Aspergillus clavatus	52.81	0.00e+00	911.00
IUUC-Afl-008535	Aspergillus flavus	53.67	0.00e+00	859.00
IUUC-Afu-008845	Aspergillus fumigatus	52.93	0.00e+00	896.00
IUUC-Ani-009135	Aspergillus nidulans	55.17	0.00e+00	885.00
IUUC-Ang-009654	Aspergillus niger	57.42	0.00e+00	824.00
IUUC-Aor-009939	Aspergillus oryzae	52.50	0.00e+00	919.00
IUUC-Ate-010355	Aspergillus terreus	53.41	0.00e+00	879.00
IUUC-Ame-010922	Astyanax mexicanus	56.33	0.00e+00	970.00
IUUC-Bgr-012249	Blumeria graminis	53.63	0.00e+00	894.00
IUUC-Bta-013579	Bos taurus	62.66	0.00e+00	976.00
IUUC-Bci-013866	Botrytis cinerea	54.65	0.00e+00	901.00
IUUC-Bdi-015046	Brachypodium distachyon	81.80	0.00e+00	1555.00
IUUC-Bol-016271	Brassica oleracea	86.47	0.00e+00	1638.00
IUUC-Bra-017758	Brassica rapa	86.35	0.00e+00	1628.00
IUUC-Cel-018387	Caenorhabditis elegans	52.89	0.00e+00	978.00
IUUC-Cja-019145	Callithrix jacchus	62.59	0.00e+00	1119.00
IUUC-Cfa-020564	Canis familiaris	62.71	0.00e+00	1120.00
IUUC-Cpo-022201	Cavia porcellus	62.67	0.00e+00	1118.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	66.51	0.00e+00	1121.00
IUUC-Csa-023383	Chlorocebus sabaeus	66.14	0.00e+00	840.00
IUUC-Cho-024454	Choloepus hoffmanni	59.43	0.00e+00	930.00
IUUC-Cin-025681	Ciona intestinalis	60.25	0.00e+00	994.00
IUUC-Csv-026012	Ciona savignyi	58.21	0.00e+00	971.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	49.94	0.00e+00	805.00
IUUC-Cne-026986	Cryptococcus neoformans	50.60	0.00e+00	882.00
IUUC-Cme-027219	Cyanidioschyzon merolae	51.62	0.00e+00	880.00
IUUC-Dre-027846	Danio rerio	62.39	0.00e+00	1116.00
IUUC-Dor-030462	Dipodomys ordii	60.12	0.00e+00	861.00
IUUC-Dse-031268	Dothistroma septosporum	53.23	0.00e+00	896.00
IUUC-Dme-031791	Drosophila melanogaster	56.92	0.00e+00	1005.00
IUUC-Ete-033166	Echinops telfairi	58.75	0.00e+00	707.00
IUUC-Eca-034180	Equus caballus	61.14	0.00e+00	1075.00
IUUC-Eeu-035086	Erinaceus europaeus	51.52	1.00e-126	446.00
IUUC-Fca-036265	Felis catus	62.71	0.00e+00	1119.00
IUUC-Fal-037202	Ficedula albicollis	61.73	0.00e+00	1068.00
IUUC-Fox-037711	Fusarium oxysporum	54.16	0.00e+00	850.00
IUUC-Fso-038268	Fusarium solani	53.51	0.00e+00	858.00
IUUC-Gmo-039046	Gadus morhua	61.67	0.00e+00	1105.00
IUUC-Ggr-039863	Gaeumannomyces graminis	53.49	0.00e+00	883.00
IUUC-Gga-041112	Gallus gallus	62.95	0.00e+00	1124.00
IUUC-Gac-041733	Gasterosteus aculeatus	61.67	0.00e+00	1078.00
IUUC-Gma-044126	Glycine max	90.59	0.00e+00	1712.00
IUUC-Ggo-044984	Gorilla gorilla	62.59	0.00e+00	1117.00
IUUC-Hsa-046698	Homo sapiens	62.71	0.00e+00	1118.00
IUUC-Hvu-047669	Hordeum vulgare	91.53	0.00e+00	702.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	62.67	0.00e+00	1115.00
IUUC-Kpa-049265	Komagataella pastoris	51.41	0.00e+00	838.00
IUUC-Lch-050473	Latimeria chalumnae	62.88	0.00e+00	1122.00
IUUC-Lpe-051579	Leersia perrieri	82.75	0.00e+00	1566.00
IUUC-Loc-052675	Lepisosteus oculatus	62.39	0.00e+00	1118.00
IUUC-Lma-053218	Leptosphaeria maculans	52.45	0.00e+00	869.00
IUUC-Laf-053757	Loxodonta africana	62.64	0.00e+00	1114.00
IUUC-Mcc-054859	Macaca mulatta	62.59	0.00e+00	1118.00
IUUC-Meu-056174	Macropus eugenii	54.90	2.00e-110	392.00
IUUC-Mor-057264	Magnaporthe oryzae	53.87	0.00e+00	870.00
IUUC-Mpo-057538	Magnaporthe poae	53.12	0.00e+00	887.00
IUUC-Mtr-058618	Medicago truncatula	90.48	0.00e+00	1682.00
IUUC-Mla-058937	Melampsora laricipopulina	53.65	0.00e+00	898.00
IUUC-Mga-059875	Meleagris gallopavo	62.68	0.00e+00	1121.00
IUUC-Mvi-060240	Microbotryum violaceum	53.05	0.00e+00	914.00
IUUC-Mmr-061261	Microcebus murinus	62.71	0.00e+00	1119.00
IUUC-Mdo-062076	Monodelphis domestica	61.28	0.00e+00	1126.00
IUUC-Mmu-063324	Mus musculus	62.71	0.00e+00	1120.00
IUUC-Mac-064636	Musa acuminata	84.43	0.00e+00	1613.00
IUUC-Mpu-065961	Mustela putorius furo	62.71	0.00e+00	1118.00
IUUC-Mlu-067059	Myotis lucifugus	61.86	0.00e+00	1103.00
IUUC-Nfi-068277	Neosartorya fischeri	53.00	0.00e+00	889.00
IUUC-Ncr-068659	Neurospora crassa	53.25	0.00e+00	897.00
IUUC-Nle-069034	Nomascus leucogenys	62.59	0.00e+00	1118.00
IUUC-Opr-070334	Ochotona princeps	63.50	0.00e+00	1012.00
IUUC-Ont-071563	Oreochromis niloticus	62.15	0.00e+00	1114.00
IUUC-Oan-073416	Ornithorhynchus anatinus	61.98	0.00e+00	1060.00
IUUC-Ocu-074522	Oryctolagus cuniculus	62.71	0.00e+00	1115.00
IUUC-Oba-075760	Oryza barthii	82.88	0.00e+00	1563.00
IUUC-Obr-076163	Oryza brachyantha	82.70	0.00e+00	1573.00
IUUC-Ogl-077450	Oryza glaberrima	83.87	0.00e+00	1592.00
IUUC-Ogu-078994	Oryza glumaepatula	82.88	0.00e+00	1563.00
IUUC-Oin-079211	Oryza indica	85.01	0.00e+00	1523.00
IUUC-Olo-080731	Oryza longistaminata	81.98	0.00e+00	1544.00
IUUC-Ome-081762	Oryza meridionalis	79.77	0.00e+00	1436.00
IUUC-Oni-082324	Oryza nivara	82.88	0.00e+00	1564.00
IUUC-Opu-083400	Oryza punctata	80.51	0.00e+00	1540.00
IUUC-Oru-084829	Oryza rufipogon	83.01	0.00e+00	1567.00
IUUC-Osa-086026	Oryza sativa	87.35	0.00e+00	1579.00
IUUC-Ola-087245	Oryzias latipes	61.74	0.00e+00	1110.00
IUUC-Olu-087655	Ostreococcus lucimarinus	66.83	0.00e+00	1149.00
IUUC-Oga-088163	Otolemur garnettii	60.41	0.00e+00	1063.00
IUUC-Oar-089842	Ovis aries	62.59	0.00e+00	1120.00
IUUC-Ptr-090501	Pan troglodytes	62.59	0.00e+00	1117.00
IUUC-Pan-092011	Papio anubis	62.59	0.00e+00	1119.00
IUUC-Psi-093308	Pelodiscus sinensis	62.71	0.00e+00	1119.00
IUUC-Pma-094695	Petromyzon marinus	58.94	0.00e+00	983.00
IUUC-Pno-094785	Phaeosphaeria nodorum	58.76	5.00e-104	370.00
IUUC-Ppa-095911	Physcomitrella patens	78.39	0.00e+00	1448.00
IUUC-Pfo-096587	Poecilia formosa	61.67	0.00e+00	1111.00
IUUC-Pab-097926	Pongo abelii	60.12	0.00e+00	1046.00
IUUC-Pop-099634	Populus trichocarpa	91.60	0.00e+00	1688.00
IUUC-Pca-100965	Procavia capensis	61.70	0.00e+00	1082.00
IUUC-Pva-102451	Pteropus vampyrus	58.92	0.00e+00	854.00
IUUC-Pgr-103453	Puccinia graminis	53.97	0.00e+00	913.00
IUUC-Ptt-103868	Puccinia triticina	54.21	0.00e+00	910.00
IUUC-Pte-104274	Pyrenophora teres	53.73	0.00e+00	900.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	52.93	0.00e+00	849.00
IUUC-Rno-105979	Rattus norvegicus	53.98	0.00e+00	822.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.61	0.00e+00	757.00
IUUC-Sha-106905	Sarcophilus harrisii	61.35	0.00e+00	1127.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.03	0.00e+00	778.00
IUUC-Spo-108299	Schizosaccharomyces pombe	48.05	0.00e+00	806.00
IUUC-Smo-108695	Selaginella moellendorffii	81.37	0.00e+00	1410.00
IUUC-Sit-110239	Setaria italica	82.78	0.00e+00	1607.00
IUUC-Sly-111775	Solanum lycopersicum	86.19	0.00e+00	1655.00
IUUC-Stu-112906	Solanum tuberosum	86.17	0.00e+00	1501.00
IUUC-Sar-113472	Sorex araneus	57.42	0.00e+00	764.00
IUUC-Sbi-113801	Sorghum bicolor	83.41	0.00e+00	1566.00
IUUC-Sre-115040	Sporisorium reilianum	53.29	0.00e+00	907.00
IUUC-Ssc-115593	Sus scrofa	62.59	0.00e+00	1119.00
IUUC-Tgu-117239	Taeniopygia guttata	62.55	0.00e+00	1120.00
IUUC-Tru-118025	Takifugu rubripes	61.71	0.00e+00	1110.00
IUUC-Tsy-118824	Tarsius syrichta	58.41	0.00e+00	790.00
IUUC-Tni-120142	Tetraodon nigroviridis	61.62	0.00e+00	1103.00
IUUC-Tca-121613	Theobroma cacao	91.77	0.00e+00	1766.00
IUUC-Tre-122072	Trichoderma reesei	53.73	0.00e+00	894.00
IUUC-Tvi-122546	Trichoderma virens	53.00	0.00e+00	875.00
IUUC-Tae-125488	Triticum aestivum	83.24	0.00e+00	1602.00
IUUC-Tur-126283	Triticum urartu	74.32	0.00e+00	1403.00
IUUC-Tme-127041	Tuber melanosporum	53.37	0.00e+00	907.00
IUUC-Tbe-127770	Tupaia belangeri	61.05	0.00e+00	893.00
IUUC-Ttr-129294	Tursiops truncatus	62.47	0.00e+00	1116.00
IUUC-Uma-129351	Ustilago maydis	51.45	0.00e+00	892.00
IUUC-Vda-129716	Verticillium dahliae	53.87	0.00e+00	904.00
IUUC-Vpa-130037	Vicugna pacos	52.27	2.00e-131	462.00
IUUC-Vvi-131689	Vitis vinifera	93.39	0.00e+00	1682.00
IUUC-Xtr-132633	Xenopus tropicalis	62.47	0.00e+00	1120.00
IUUC-Xma-133347	Xiphophorus maculatus	61.91	0.00e+00	1113.00
IUUC-Yli-134455	Yarrowia lipolytica	51.02	0.00e+00	810.00
IUUC-Zma-135706	Zea mays	83.75	0.00e+00	1599.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence