iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027854

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CR376846

Gene Name

uchl1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000026871.9	ENSDART00000036797.8	ENSDARP00000034536.7

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	66.07	3.00e-83	305.00	IUUC-Hsa-045820
DUB/UCH	66.07	3.00e-83	305.00	IUUC-Hsa-045820
UBD/Other/Other	66.07	3.00e-83	305.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MEWKPMEINP EMLNKVLSKL GVGSKWRFVD VLGLEDESLS GVPSPCCAMM LLFPLTQQHE 60
DFRSKQSVGD CKDVYFLKQT VVNSCGTVGL VHAVANNQDS IDFDNNSALK KFLEATSGMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAAGAGA AATGAGCAGA GCTGAATTGA GTTATTCAGC TGTGATTTAT GCAGCTTTGT 60
TTCATTACAT GCAAGTAGAC AACATTTGTA CTTGATAAAA ATAATGCACT TTGAAATTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016874--F:ligase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	54.26	3.00e-70	258.00
IUUC-Apl-003693	Anas platyrhynchos	58.04	2.00e-71	261.00
IUUC-Aca-004716	Anolis carolinensis	64.73	1.00e-85	308.00
IUUC-Ame-011806	Astyanax mexicanus	80.28	7.00e-107	379.00
IUUC-Bta-013521	Bos taurus	55.34	9.00e-72	263.00
IUUC-Cel-018302	Caenorhabditis elegans	35.65	2.00e-29	122.00
IUUC-Cja-018752	Callithrix jacchus	65.78	1.00e-74	272.00
IUUC-Cfa-020442	Canis familiaris	64.89	3.00e-74	271.00
IUUC-Csa-023626	Chlorocebus sabaeus	65.62	3.00e-75	274.00
IUUC-Cho-024548	Choloepus hoffmanni	56.88	2.00e-23	102.00
IUUC-Dno-029325	Dasypus novemcinctus	65.62	1.00e-75	275.00
IUUC-Dor-030114	Dipodomys ordii	65.62	9.00e-84	302.00
IUUC-Ete-033092	Echinops telfairi	53.12	2.00e-59	222.00
IUUC-Eeu-034493	Erinaceus europaeus	63.84	5.00e-72	263.00
IUUC-Fal-036693	Ficedula albicollis	64.29	1.00e-77	282.00
IUUC-Gmo-038848	Gadus morhua	71.43	5.00e-88	316.00
IUUC-Gga-041078	Gallus gallus	64.73	3.00e-85	307.00
IUUC-Gac-042064	Gasterosteus aculeatus	69.59	5.00e-90	323.00
IUUC-Ggo-044827	Gorilla gorilla	66.07	7.00e-76	276.00
IUUC-Hsa-045820	Homo sapiens	66.07	7.00e-76	276.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	64.29	3.00e-74	271.00
IUUC-Lch-050121	Latimeria chalumnae	63.96	1.00e-82	298.00
IUUC-Loc-052342	Lepisosteus oculatus	70.54	8.00e-94	336.00
IUUC-Laf-053916	Loxodonta africana	66.37	4.00e-77	280.00
IUUC-Mcc-054838	Macaca mulatta	65.62	3.00e-75	274.00
IUUC-Meu-056478	Macropus eugenii	64.73	6.00e-83	300.00
IUUC-Mga-059878	Meleagris gallopavo	62.67	1.00e-77	282.00
IUUC-Mdo-062544	Monodelphis domestica	62.33	4.00e-71	260.00
IUUC-Mmu-063300	Mus musculus	65.18	4.00e-84	303.00
IUUC-Mpu-066128	Mustela putorius furo	60.89	9.00e-62	229.00
IUUC-Mlu-067778	Myotis lucifugus	65.18	3.00e-84	304.00
IUUC-Nle-069686	Nomascus leucogenys	65.62	1.00e-75	275.00
IUUC-Opr-070535	Ochotona princeps	53.12	2.00e-60	225.00
IUUC-Ont-071510	Oreochromis niloticus	72.15	7.00e-96	342.00
IUUC-Ocu-074590	Oryctolagus cuniculus	65.62	4.00e-75	273.00
IUUC-Ola-087552	Oryzias latipes	65.78	1.00e-85	309.00
IUUC-Oga-089013	Otolemur garnettii	54.15	2.00e-70	259.00
IUUC-Oar-089861	Ovis aries	55.34	7.00e-72	263.00
IUUC-Ptr-091536	Pan troglodytes	64.29	2.00e-73	268.00
IUUC-Pan-092909	Papio anubis	65.62	3.00e-75	274.00
IUUC-Psi-093818	Pelodiscus sinensis	65.18	9.00e-85	306.00
IUUC-Pfo-097335	Poecilia formosa	66.67	5.00e-88	317.00
IUUC-Pab-098048	Pongo abelii	66.07	7.00e-76	276.00
IUUC-Pca-100818	Procavia capensis	48.45	2.00e-39	155.00
IUUC-Pva-102954	Pteropus vampyrus	65.62	4.00e-73	267.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	37.80	7.00e-29	120.00
IUUC-Rno-105966	Rattus norvegicus	65.18	4.00e-84	303.00
IUUC-Sar-113190	Sorex araneus	50.88	7.00e-21	92.00
IUUC-Ssc-115908	Sus scrofa	54.87	3.00e-64	238.00
IUUC-Tgu-117465	Taeniopygia guttata	60.66	4.00e-72	263.00
IUUC-Tru-118565	Takifugu rubripes	64.09	3.00e-79	287.00
IUUC-Tsy-119561	Tarsius syrichta	52.23	2.00e-58	218.00
IUUC-Tbe-128048	Tupaia belangeri	62.05	3.00e-55	207.00
IUUC-Ttr-128494	Tursiops truncatus	62.95	2.00e-71	261.00
IUUC-Xtr-132286	Xenopus tropicalis	60.81	6.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence