iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048556

Ensembl Protein ID

ENSSTOP00000012587.1

UniProt Accession

I3MM66; I3MM66_ICTTR

Genbank Protein ID

ENSSTOP00000012587

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01110292

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014053.1	ENSSTOT00000014047.1	ENSSTOP00000012587.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	585	622
ULD/UDP/UBQ/UBQ_PIM	2.00e-23	82.1	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 585  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 622
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGSAAAPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTTQPSSAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG CAGCGGCCCC CCGCGCCCCT CCCGCGGTCC TGCTGCGGCC 60
CAAGGCTCGG CCGCTGCCCC GGCTGAGCCC AAAATCATCA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002068	Ailuropoda melanoleuca	94.68	3.00e-165	575.00
IUUC-Aca-004511	Anolis carolinensis	69.69	2.00e-176	612.00
IUUC-Bta-013571	Bos taurus	94.85	0.00e+00	736.00
IUUC-Cfa-020799	Canis familiaris	94.63	4.00e-179	620.00
IUUC-Cpo-022093	Cavia porcellus	94.48	1.00e-172	599.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	95.54	0.00e+00	742.00
IUUC-Dno-029647	Dasypus novemcinctus	91.83	9.00e-131	460.00
IUUC-Ete-033071	Echinops telfairi	88.91	0.00e+00	701.00
IUUC-Eeu-034727	Erinaceus europaeus	92.03	0.00e+00	714.00
IUUC-Fca-035803	Felis catus	94.85	1.00e-176	612.00
IUUC-Fso-038204	Fusarium solani	42.25	2.00e-08	53.50
IUUC-Hsa-046768	Homo sapiens	95.52	7.00e-175	606.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	5.00e-09	52.80
IUUC-Mor-057194	Magnaporthe oryzae	48.00	3.00e-07	49.70
IUUC-Mvi-060466	Microbotryum violaceum	54.76	2.00e-08	53.10
IUUC-Mmr-061605	Microcebus murinus	93.50	4.00e-169	587.00
IUUC-Mpu-066474	Mustela putorius furo	94.63	0.00e+00	641.00
IUUC-Mlu-067252	Myotis lucifugus	85.20	1.00e-169	589.00
IUUC-Ncr-068732	Neurospora crassa	48.00	2.00e-07	50.10
IUUC-Nle-069038	Nomascus leucogenys	95.71	0.00e+00	741.00
IUUC-Oga-088005	Otolemur garnettii	95.08	9.00e-175	606.00
IUUC-Oar-089878	Ovis aries	94.51	0.00e+00	746.00
IUUC-Ptr-090781	Pan troglodytes	95.53	2.00e-175	608.00
IUUC-Pan-091716	Papio anubis	90.05	0.00e+00	700.00
IUUC-Pab-097891	Pongo abelii	95.29	3.00e-175	608.00
IUUC-Pca-100227	Procavia capensis	96.62	2.00e-93	335.00
IUUC-Pva-102513	Pteropus vampyrus	78.29	8.00e-101	360.00
IUUC-Sce-106332	Saccharomyces cerevisiae	44.16	8.00e-11	60.80
IUUC-Tsy-119008	Tarsius syrichta	92.18	8.00e-169	586.00
IUUC-Vda-129991	Verticillium dahliae	46.15	7.00e-07	48.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence