iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004122

Ensembl Protein ID

ENSAPLP00000012280.1

UniProt Accession

U3IYF4; U3IYF4_ANAPL

Genbank Protein ID

ENSAPLP00000012280

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01146394

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012484.1	ENSAPLT00000013015.1	ENSAPLP00000012280.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.30e-45	151.9	20	146
UBD/Alpha-Helix/UBA	6.40e-11	41.8	161	199

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 10   ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspals 97
           + +++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a++
   Q: 20   NMTSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMT 105
           3455689********.9***************************************************99********9..******** PP
   S: 98   vesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 106  LRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 146
           **************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 161  EYTRKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 199
           5788*********************************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LAVMCLQRVH QTLNKKTKSN MTSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGCTGTGA TGTGTCTGCA GCGAGTGCAT CAAAGTGTGC ACAGCACCGA TTCTGAAACT 60
CCACGGAATT CCTCTGCACA GGGCTAGCTG GGTGGTAGGG GACATAAAAC GGAGGAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	51.58	2.00e-26	112.00
IUUC-Aml-001286	Ailuropoda melanoleuca	91.50	9.00e-101	358.00
IUUC-Atr-003063	Amborella trichopoda	51.46	7.00e-38	149.00
IUUC-Aca-004565	Anolis carolinensis	91.37	3.00e-99	353.00
IUUC-Aly-006390	Arabidopsis lyrata	48.21	2.00e-42	164.00
IUUC-Ath-006637	Arabidopsis thaliana	50.00	3.00e-39	154.00
IUUC-Ago-007714	Ashbya gossypii	47.47	6.00e-36	143.00
IUUC-Acl-008189	Aspergillus clavatus	55.65	4.00e-26	111.00
IUUC-Afl-008489	Aspergillus flavus	44.57	5.00e-27	114.00
IUUC-Afu-008850	Aspergillus fumigatus	39.25	4.00e-27	114.00
IUUC-Ani-009361	Aspergillus nidulans	47.97	1.00e-24	106.00
IUUC-Ang-009548	Aspergillus niger	54.55	5.00e-25	107.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	5.00e-27	114.00
IUUC-Ate-010389	Aspergillus terreus	43.48	2.00e-27	115.00
IUUC-Ame-011454	Astyanax mexicanus	89.50	5.00e-99	352.00
IUUC-Bgr-012255	Blumeria graminis	46.50	8.00e-32	129.00
IUUC-Bta-012992	Bos taurus	91.50	9.00e-101	358.00
IUUC-Bci-013806	Botrytis cinerea	44.15	2.00e-35	141.00
IUUC-Bdi-015024	Brachypodium distachyon	48.21	2.00e-39	155.00
IUUC-Bol-015985	Brassica oleracea	48.72	9.00e-43	166.00
IUUC-Bra-016805	Brassica rapa	48.72	4.00e-43	167.00
IUUC-Cel-018353	Caenorhabditis elegans	47.24	2.00e-50	191.00
IUUC-Cja-019051	Callithrix jacchus	91.00	6.00e-100	355.00
IUUC-Cfa-020016	Canis familiaris	91.50	9.00e-101	358.00
IUUC-Cpo-022026	Cavia porcellus	91.50	9.00e-101	358.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.97	5.00e-41	160.00
IUUC-Csa-023059	Chlorocebus sabaeus	91.50	9.00e-101	358.00
IUUC-Cho-024276	Choloepus hoffmanni	95.92	2.00e-73	266.00
IUUC-Cin-025598	Ciona intestinalis	58.16	1.00e-51	195.00
IUUC-Csv-025831	Ciona savignyi	61.38	8.00e-51	192.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	44.94	4.00e-33	134.00
IUUC-Cne-027068	Cryptococcus neoformans	42.42	1.00e-39	155.00
IUUC-Dre-028139	Danio rerio	89.50	6.00e-99	352.00
IUUC-Dno-029169	Dasypus novemcinctus	90.50	3.00e-98	350.00
IUUC-Dor-030382	Dipodomys ordii	77.50	2.00e-79	287.00
IUUC-Dse-031335	Dothistroma septosporum	53.38	2.00e-36	145.00
IUUC-Dme-032003	Drosophila melanogaster	61.81	2.00e-63	234.00
IUUC-Ete-032868	Echinops telfairi	82.50	4.00e-79	286.00
IUUC-Eca-033428	Equus caballus	91.50	9.00e-101	358.00
IUUC-Eeu-035103	Erinaceus europaeus	72.66	5.00e-49	185.00
IUUC-Fca-035366	Felis catus	91.50	9.00e-101	358.00
IUUC-Fal-037016	Ficedula albicollis	91.50	9.00e-101	358.00
IUUC-Fox-037969	Fusarium oxysporum	46.20	2.00e-32	132.00
IUUC-Fso-038296	Fusarium solani	44.57	2.00e-34	138.00
IUUC-Gmo-039135	Gadus morhua	88.50	2.00e-97	347.00
IUUC-Ggr-039768	Gaeumannomyces graminis	52.17	6.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	92.00	4.00e-101	359.00
IUUC-Gac-041503	Gasterosteus aculeatus	89.00	2.00e-98	350.00
IUUC-Gma-042779	Glycine max	50.26	7.00e-42	162.00
IUUC-Ggo-045032	Gorilla gorilla	91.50	9.00e-101	358.00
IUUC-Hsa-046490	Homo sapiens	91.50	9.00e-101	358.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	91.50	9.00e-101	358.00
IUUC-Kpa-049297	Komagataella pastoris	46.45	2.00e-32	132.00
IUUC-Lch-050588	Latimeria chalumnae	69.05	4.00e-76	276.00
IUUC-Lpe-051070	Leersia perrieri	47.69	1.00e-30	125.00
IUUC-Loc-052549	Lepisosteus oculatus	90.00	2.00e-99	353.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	4.00e-36	144.00
IUUC-Laf-053688	Loxodonta africana	91.79	3.00e-98	350.00
IUUC-Mcc-055606	Macaca mulatta	91.50	9.00e-101	358.00
IUUC-Mor-056946	Magnaporthe oryzae	38.42	1.00e-22	99.40
IUUC-Mpo-057441	Magnaporthe poae	51.02	5.00e-24	103.00
IUUC-Mtr-058002	Medicago truncatula	52.33	3.00e-41	160.00
IUUC-Mla-059007	Melampsora laricipopulina	46.15	7.00e-37	146.00
IUUC-Mga-059254	Meleagris gallopavo	100.00	5.00e-98	349.00
IUUC-Mvi-060346	Microbotryum violaceum	42.78	3.00e-31	127.00
IUUC-Mmr-061211	Microcebus murinus	91.50	9.00e-101	358.00
IUUC-Mdo-062458	Monodelphis domestica	90.50	3.00e-98	350.00
IUUC-Mmu-063648	Mus musculus	91.50	9.00e-101	358.00
IUUC-Mac-065447	Musa acuminata	47.47	5.00e-40	156.00
IUUC-Mpu-066407	Mustela putorius furo	91.50	3.00e-100	357.00
IUUC-Mlu-067682	Myotis lucifugus	96.28	9.00e-99	352.00
IUUC-Nfi-068517	Neosartorya fischeri	39.72	2.00e-27	115.00
IUUC-Ncr-068749	Neurospora crassa	53.97	6.00e-36	143.00
IUUC-Nle-069712	Nomascus leucogenys	100.00	3.00e-98	350.00
IUUC-Opr-070651	Ochotona princeps	91.50	9.00e-101	358.00
IUUC-Ont-071595	Oreochromis niloticus	89.00	2.00e-98	350.00
IUUC-Oan-073058	Ornithorhynchus anatinus	99.32	1.00e-78	284.00
IUUC-Ocu-074939	Oryctolagus cuniculus	91.50	9.00e-101	358.00
IUUC-Oba-075530	Oryza barthii	48.47	7.00e-30	122.00
IUUC-Obr-076838	Oryza brachyantha	47.96	3.00e-29	120.00
IUUC-Ogl-077606	Oryza glaberrima	48.47	7.00e-30	122.00
IUUC-Ogu-078238	Oryza glumaepatula	48.47	7.00e-30	122.00
IUUC-Oin-079643	Oryza indica	48.47	2.00e-29	121.00
IUUC-Ome-081274	Oryza meridionalis	48.47	7.00e-30	122.00
IUUC-Oni-082651	Oryza nivara	48.47	7.00e-30	122.00
IUUC-Opu-083933	Oryza punctata	48.47	1.00e-29	122.00
IUUC-Oru-085054	Oryza rufipogon	48.47	2.00e-29	121.00
IUUC-Osa-085716	Oryza sativa	48.47	2.00e-29	121.00
IUUC-Ola-087043	Oryzias latipes	89.00	2.00e-98	350.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	6.00e-41	159.00
IUUC-Oga-088897	Otolemur garnettii	98.36	2.00e-98	350.00
IUUC-Oar-089673	Ovis aries	99.44	1.00e-97	348.00
IUUC-Ptr-091295	Pan troglodytes	91.50	9.00e-101	358.00
IUUC-Pan-092034	Papio anubis	99.44	2.00e-97	347.00
IUUC-Psi-093498	Pelodiscus sinensis	91.50	9.00e-101	358.00
IUUC-Pma-094115	Petromyzon marinus	80.20	3.00e-86	310.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.17	5.00e-37	147.00
IUUC-Ppa-095326	Physcomitrella patens	45.64	2.00e-37	148.00
IUUC-Pfo-096940	Poecilia formosa	89.00	2.00e-98	350.00
IUUC-Pab-098279	Pongo abelii	91.50	9.00e-101	358.00
IUUC-Pop-099543	Populus trichocarpa	49.22	1.00e-42	165.00
IUUC-Pca-100782	Procavia capensis	91.00	9.00e-99	351.00
IUUC-Ppe-101789	Prunus persica	52.00	3.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	99.04	4.00e-52	196.00
IUUC-Pgr-103643	Puccinia graminis	47.48	3.00e-36	144.00
IUUC-Ptt-103772	Puccinia triticina	49.23	8.00e-35	140.00
IUUC-Pte-104370	Pyrenophora teres	56.91	1.00e-35	142.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	56.91	2.00e-35	142.00
IUUC-Rno-104984	Rattus norvegicus	91.50	9.00e-101	358.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	2.00e-33	135.00
IUUC-Sha-106848	Sarcophilus harrisii	97.81	2.00e-97	347.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	46.28	1.00e-38	152.00
IUUC-Smo-109656	Selaginella moellendorffii	48.45	1.00e-38	151.00
IUUC-Sit-110639	Setaria italica	47.45	2.00e-37	148.00
IUUC-Sly-110978	Solanum lycopersicum	49.23	3.00e-43	167.00
IUUC-Stu-112088	Solanum tuberosum	49.23	1.00e-43	168.00
IUUC-Sar-113285	Sorex araneus	83.80	5.00e-76	276.00
IUUC-Sbi-113986	Sorghum bicolor	47.45	3.00e-37	147.00
IUUC-Sre-115046	Sporisorium reilianum	44.81	2.00e-35	141.00
IUUC-Ssc-116314	Sus scrofa	91.50	9.00e-101	358.00
IUUC-Tgu-117427	Taeniopygia guttata	99.44	1.00e-97	347.00
IUUC-Tru-118618	Takifugu rubripes	84.50	1.00e-93	335.00
IUUC-Tsy-119208	Tarsius syrichta	92.89	8.00e-101	358.00
IUUC-Tni-119667	Tetraodon nigroviridis	89.50	6.00e-99	352.00
IUUC-Tca-121446	Theobroma cacao	50.26	7.00e-44	169.00
IUUC-Tre-122053	Trichoderma reesei	36.82	4.00e-30	124.00
IUUC-Tae-125119	Triticum aestivum	48.72	6.00e-32	130.00
IUUC-Tme-127024	Tuber melanosporum	50.32	1.00e-38	152.00
IUUC-Tbe-127752	Tupaia belangeri	90.50	7.00e-99	352.00
IUUC-Ttr-128287	Tursiops truncatus	99.44	1.00e-97	347.00
IUUC-Uma-129512	Ustilago maydis	38.35	2.00e-35	141.00
IUUC-Vda-129947	Verticillium dahliae	42.20	8.00e-31	126.00
IUUC-Vpa-130481	Vicugna pacos	92.39	2.00e-100	357.00
IUUC-Vvi-131429	Vitis vinifera	47.92	4.00e-40	156.00
IUUC-Xtr-132710	Xenopus tropicalis	75.25	7.00e-86	309.00
IUUC-Xma-134165	Xiphophorus maculatus	88.50	4.00e-98	349.00
IUUC-Yli-134523	Yarrowia lipolytica	46.54	5.00e-33	133.00
IUUC-Zma-135733	Zea mays	46.63	1.00e-35	142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence