iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062863

UUCD1 version

UUC-MoD-00972

Ensembl Protein ID

ENSMODP00000001455.3

UniProt Accession

F7G7S0; F7G7S0_MONDO

Protein Name

Uncharacterized protein

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001215.3	ENSMODT00000001485.3	ENSMODP00000001455.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-44	148.7	204	240
UBD/Beta-Prp	4.30e-64	216.7	299	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 204  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 240
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           +p  ++l+t srd+t ++wdv+t+  +++l gh+++v++vk++  ++ ++tgs D ti++wdl +gk+ +tl++h++sv+++ ++p  +
   Q: 299  HPTIDVLVTCSRDSTARIWDVRTKASVHTLAGHTNAVATVKCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHY 387
           55556677777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvyslsfd 189
           +++sGs d+ i+ w+ + g  ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++        + + ++ +   +fd
   Q: 388  TFASGSPDN-IKQWKFPDGNFIQ-NLSGHNAIINTLAVNS-DGVLVSGADNGTMHLWDWRTGYNFQRVhaavqpgSLDSESGIFACAFD 473
           777777544.6777777777777.7777777777777777.556677777777777777777666666544444422244444444477 PP
   S: 190  sngkelvsgsldgtvklwd 208
           ++  +l+++  d+t+k++ 
   Q: 474  QSESRLLTAEADKTIKVYR 492
           7777777777777777764 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADNA KPVQLDEESH KLKMSVKLHT EYGPVLHMPI 60
LKENLREKGS QSAVDAYGHK QYPANQGQEI EYLVTGTHPY PPGPGVALTA DTKIQRMPSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGAGG TGAGTGACGG ACGCGCGCGA GGGCAGCCGG TCTCTGGGAG CGCGAGAGTT 60
CTGCCGGTGA AATGGGACTT TGGCCCGCCG TTTGTCCGCC TATGGTTCCT CCTCTCTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

KEGG

mdo:100024419

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	46.65	6.00e-129	454.00
IUUC-Aml-001605	Ailuropoda melanoleuca	91.25	0.00e+00	985.00
IUUC-Atr-002757	Amborella trichopoda	48.16	6.00e-129	454.00
IUUC-Apl-003198	Anas platyrhynchos	91.67	0.00e+00	1005.00
IUUC-Aca-004683	Anolis carolinensis	92.44	0.00e+00	1011.00
IUUC-Aly-005775	Arabidopsis lyrata	60.36	2.00e-125	442.00
IUUC-Ath-007460	Arabidopsis thaliana	52.71	3.00e-125	442.00
IUUC-Ago-007884	Ashbya gossypii	49.14	9.00e-107	380.00
IUUC-Acl-008153	Aspergillus clavatus	64.33	4.00e-129	454.00
IUUC-Afl-008384	Aspergillus flavus	60.55	4.00e-130	457.00
IUUC-Afu-009045	Aspergillus fumigatus	64.94	4.00e-130	457.00
IUUC-Ani-009229	Aspergillus nidulans	64.53	5.00e-129	454.00
IUUC-Ang-009812	Aspergillus niger	65.93	1.00e-124	439.00
IUUC-Aor-010059	Aspergillus oryzae	60.55	4.00e-130	457.00
IUUC-Ate-010351	Aspergillus terreus	65.24	7.00e-136	477.00
IUUC-Ame-011613	Astyanax mexicanus	60.62	4.00e-163	567.00
IUUC-Bgr-012042	Blumeria graminis	55.20	1.00e-134	473.00
IUUC-Bta-012406	Bos taurus	90.50	0.00e+00	975.00
IUUC-Bci-013760	Botrytis cinerea	58.42	8.00e-134	470.00
IUUC-Bdi-014776	Brachypodium distachyon	49.58	1.00e-131	463.00
IUUC-Bol-016189	Brassica oleracea	60.36	3.00e-125	441.00
IUUC-Bra-018044	Brassica rapa	60.36	2.00e-125	442.00
IUUC-Cel-018651	Caenorhabditis elegans	53.37	3.00e-156	544.00
IUUC-Cja-019974	Callithrix jacchus	90.31	0.00e+00	976.00
IUUC-Cfa-021085	Canis familiaris	91.28	0.00e+00	989.00
IUUC-Cpo-021458	Cavia porcellus	90.31	0.00e+00	981.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.88	3.00e-124	437.00
IUUC-Csa-023883	Chlorocebus sabaeus	90.12	0.00e+00	973.00
IUUC-Cho-024623	Choloepus hoffmanni	90.41	0.00e+00	960.00
IUUC-Cin-025190	Ciona intestinalis	60.93	0.00e+00	647.00
IUUC-Csv-026367	Ciona savignyi	61.38	0.00e+00	649.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	64.09	3.00e-139	488.00
IUUC-Cne-027069	Cryptococcus neoformans	55.69	2.00e-127	448.00
IUUC-Cme-027233	Cyanidioschyzon merolae	30.49	2.00e-35	143.00
IUUC-Dre-028260	Danio rerio	80.81	0.00e+00	879.00
IUUC-Dno-029112	Dasypus novemcinctus	91.28	0.00e+00	984.00
IUUC-Dor-031118	Dipodomys ordii	91.00	0.00e+00	781.00
IUUC-Dse-031493	Dothistroma septosporum	45.42	2.00e-125	442.00
IUUC-Dme-032138	Drosophila melanogaster	76.62	7.00e-160	556.00
IUUC-Ete-032411	Echinops telfairi	80.51	0.00e+00	794.00
IUUC-Eca-033521	Equus caballus	91.28	0.00e+00	993.00
IUUC-Eeu-035249	Erinaceus europaeus	79.32	0.00e+00	658.00
IUUC-Fca-036358	Felis catus	90.50	0.00e+00	981.00
IUUC-Fal-036933	Ficedula albicollis	91.86	0.00e+00	998.00
IUUC-Fox-037713	Fusarium oxysporum	56.72	1.00e-137	483.00
IUUC-Fso-038380	Fusarium solani	64.83	1.00e-137	483.00
IUUC-Gmo-039133	Gadus morhua	81.29	0.00e+00	879.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.36	3.00e-132	465.00
IUUC-Gga-041176	Gallus gallus	90.70	0.00e+00	998.00
IUUC-Gac-042344	Gasterosteus aculeatus	79.26	0.00e+00	872.00
IUUC-Gma-043328	Glycine max	48.34	3.00e-130	458.00
IUUC-Ggo-044478	Gorilla gorilla	89.92	0.00e+00	971.00
IUUC-Hsa-046037	Homo sapiens	90.12	0.00e+00	972.00
IUUC-Hvu-047349	Hordeum vulgare	50.51	7.00e-133	467.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	90.89	0.00e+00	985.00
IUUC-Kpa-049343	Komagataella pastoris	58.77	5.00e-119	421.00
IUUC-Lch-049830	Latimeria chalumnae	87.40	0.00e+00	951.00
IUUC-Lpe-051442	Leersia perrieri	47.46	3.00e-129	455.00
IUUC-Loc-051794	Lepisosteus oculatus	84.10	0.00e+00	895.00
IUUC-Lma-053137	Leptosphaeria maculans	44.08	1.00e-125	443.00
IUUC-Laf-053471	Loxodonta africana	90.27	0.00e+00	976.00
IUUC-Mcc-055627	Macaca mulatta	90.31	0.00e+00	976.00
IUUC-Meu-056148	Macropus eugenii	84.02	0.00e+00	890.00
IUUC-Mor-056960	Magnaporthe oryzae	65.95	5.00e-137	481.00
IUUC-Mtr-057816	Medicago truncatula	46.85	4.00e-127	448.00
IUUC-Mla-059031	Melampsora laricipopulina	65.09	4.00e-127	447.00
IUUC-Mga-059337	Meleagris gallopavo	91.25	0.00e+00	1001.00
IUUC-Mvi-060217	Microbotryum violaceum	59.94	2.00e-129	455.00
IUUC-Mmr-061018	Microcebus murinus	91.47	0.00e+00	991.00
IUUC-Mmu-063988	Mus musculus	89.73	0.00e+00	964.00
IUUC-Mac-064459	Musa acuminata	64.31	3.00e-122	432.00
IUUC-Mpu-066559	Mustela putorius furo	91.28	0.00e+00	989.00
IUUC-Mlu-067361	Myotis lucifugus	90.64	0.00e+00	961.00
IUUC-Nfi-068492	Neosartorya fischeri	65.24	3.00e-130	458.00
IUUC-Ncr-068808	Neurospora crassa	60.50	3.00e-137	481.00
IUUC-Nle-069875	Nomascus leucogenys	90.31	0.00e+00	975.00
IUUC-Opr-070462	Ochotona princeps	96.62	3.00e-156	544.00
IUUC-Ont-071365	Oreochromis niloticus	79.65	0.00e+00	877.00
IUUC-Oan-072708	Ornithorhynchus anatinus	96.11	0.00e+00	1041.00
IUUC-Ocu-074594	Oryctolagus cuniculus	90.31	0.00e+00	977.00
IUUC-Oba-075570	Oryza barthii	62.46	3.00e-127	448.00
IUUC-Obr-076366	Oryza brachyantha	63.98	8.00e-92	329.00
IUUC-Ogl-077153	Oryza glaberrima	62.46	2.00e-126	445.00
IUUC-Ogu-078540	Oryza glumaepatula	62.46	3.00e-127	448.00
IUUC-Oin-079612	Oryza indica	61.54	2.00e-125	442.00
IUUC-Olo-081077	Oryza longistaminata	61.54	2.00e-125	442.00
IUUC-Ome-081236	Oryza meridionalis	61.24	4.00e-125	441.00
IUUC-Oni-082499	Oryza nivara	62.46	3.00e-127	448.00
IUUC-Opu-083499	Oryza punctata	61.54	2.00e-125	442.00
IUUC-Oru-084276	Oryza rufipogon	62.46	3.00e-127	448.00
IUUC-Osa-085849	Oryza sativa	62.46	3.00e-127	448.00
IUUC-Ola-086655	Oryzias latipes	77.22	0.00e+00	845.00
IUUC-Olu-087637	Ostreococcus lucimarinus	57.91	2.00e-119	422.00
IUUC-Oga-087934	Otolemur garnettii	91.30	0.00e+00	987.00
IUUC-Oar-090185	Ovis aries	90.33	0.00e+00	972.00
IUUC-Ptr-091198	Pan troglodytes	90.31	0.00e+00	975.00
IUUC-Pan-092622	Papio anubis	90.12	0.00e+00	973.00
IUUC-Psi-093320	Pelodiscus sinensis	92.84	0.00e+00	1011.00
IUUC-Pma-094638	Petromyzon marinus	78.45	0.00e+00	867.00
IUUC-Pno-094826	Phaeosphaeria nodorum	50.15	5.00e-105	374.00
IUUC-Ppa-095576	Physcomitrella patens	64.31	8.00e-125	440.00
IUUC-Pfo-096894	Poecilia formosa	79.54	0.00e+00	870.00
IUUC-Pab-098020	Pongo abelii	90.31	0.00e+00	975.00
IUUC-Pop-099180	Populus trichocarpa	47.39	4.00e-125	441.00
IUUC-Pca-100909	Procavia capensis	84.20	0.00e+00	765.00
IUUC-Ppe-101346	Prunus persica	46.38	1.00e-123	436.00
IUUC-Pva-102167	Pteropus vampyrus	75.00	0.00e+00	762.00
IUUC-Pgr-103516	Puccinia graminis	50.41	1.00e-129	456.00
IUUC-Ptt-103738	Puccinia triticina	50.21	1.00e-130	459.00
IUUC-Pte-104352	Pyrenophora teres	57.52	6.00e-130	457.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	58.11	5.00e-131	461.00
IUUC-Rno-105291	Rattus norvegicus	90.31	0.00e+00	973.00
IUUC-Sce-106204	Saccharomyces cerevisiae	49.55	3.00e-103	369.00
IUUC-Sha-106943	Sarcophilus harrisii	98.07	0.00e+00	1026.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	64.00	2.00e-130	459.00
IUUC-Spo-108049	Schizosaccharomyces pombe	49.31	3.00e-136	478.00
IUUC-Smo-109043	Selaginella moellendorffii	60.78	4.00e-126	444.00
IUUC-Sit-110431	Setaria italica	57.61	9.00e-132	463.00
IUUC-Sly-111391	Solanum lycopersicum	52.54	4.00e-119	421.00
IUUC-Stu-112364	Solanum tuberosum	55.26	2.00e-96	345.00
IUUC-Sar-113450	Sorex araneus	96.28	0.00e+00	714.00
IUUC-Sbi-113829	Sorghum bicolor	49.59	3.00e-131	461.00
IUUC-Sre-115153	Sporisorium reilianum	61.54	8.00e-122	430.00
IUUC-Ssc-115798	Sus scrofa	90.14	0.00e+00	978.00
IUUC-Tgu-117417	Taeniopygia guttata	92.59	0.00e+00	1004.00
IUUC-Tru-117615	Takifugu rubripes	77.09	0.00e+00	811.00
IUUC-Tsy-119480	Tarsius syrichta	91.23	0.00e+00	974.00
IUUC-Tni-119847	Tetraodon nigroviridis	77.33	0.00e+00	841.00
IUUC-Tca-121287	Theobroma cacao	46.34	5.00e-128	451.00
IUUC-Tre-122010	Trichoderma reesei	64.62	2.00e-142	499.00
IUUC-Tvi-122475	Trichoderma virens	66.26	3.00e-141	494.00
IUUC-Tae-124397	Triticum aestivum	49.90	1.00e-134	473.00
IUUC-Tur-126116	Triticum urartu	50.13	3.00e-101	362.00
IUUC-Tme-126992	Tuber melanosporum	64.94	6.00e-136	477.00
IUUC-Tbe-127803	Tupaia belangeri	80.89	0.00e+00	702.00
IUUC-Ttr-128933	Tursiops truncatus	91.09	0.00e+00	981.00
IUUC-Uma-129447	Ustilago maydis	59.69	1.00e-117	417.00
IUUC-Vda-129780	Verticillium dahliae	63.24	1.00e-137	482.00
IUUC-Vpa-130557	Vicugna pacos	80.09	1.00e-105	377.00
IUUC-Vvi-130918	Vitis vinifera	53.75	4.00e-121	427.00
IUUC-Xtr-132409	Xenopus tropicalis	89.36	0.00e+00	929.00
IUUC-Xma-133420	Xiphophorus maculatus	79.26	0.00e+00	871.00
IUUC-Yli-134362	Yarrowia lipolytica	59.15	2.00e-121	429.00
IUUC-Zma-135804	Zea mays	60.95	8.00e-125	440.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence