iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050010

Ensembl Protein ID

ENSLACP00000011862.1

UniProt Accession

H3AQE1; H3AQE1_LATCH

Genbank Protein ID

ENSLACP00000011862

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01131087

Gene Name

TRIO

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010439.1	ENSLACT00000011953.1	ENSLACP00000011862.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.20e-14	51.9	1617	1668

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a+n++eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1617 TVVIHDFTAANSNELTIRRGQTVEVLERPHDKPDWCLVRTtdRSPAAEGLVP 1668
           679********************************97755334445678887 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

NFYFPGFRKN DEMKAMEVLP ILKEKVAYLS GGRDKRGGPI LTFPARSNHD RIRQEDLRRL 60
ISYLASIPSE EVCKRGFTVI VDMRGSKWDS IKPLLKILQE SFPCCIHVAL IIKPDNFWQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTTTTATT TTCCAGGGTT TCGCAAAAAT GATGAAATGA AGGCCATGGA AGTACTGCCA 60
ATTTTAAAGG AAAAAGTCGC CTATCTTTCA GGTAAGATTT TCTTTTTCTT TTTAATTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	88.94	0.00e+00	5261.00
IUUC-Apl-003498	Anas platyrhynchos	90.79	0.00e+00	5022.00
IUUC-Bta-013121	Bos taurus	86.81	0.00e+00	5137.00
IUUC-Cja-018919	Callithrix jacchus	93.05	0.00e+00	4146.00
IUUC-Cfa-020547	Canis familiaris	87.97	0.00e+00	5186.00
IUUC-Cpo-022301	Cavia porcellus	88.33	0.00e+00	5262.00
IUUC-Csa-023889	Chlorocebus sabaeus	88.76	0.00e+00	5220.00
IUUC-Dre-028386	Danio rerio	86.69	0.00e+00	3838.00
IUUC-Dno-028888	Dasypus novemcinctus	87.72	0.00e+00	5184.00
IUUC-Dor-030992	Dipodomys ordii	86.13	0.00e+00	3749.00
IUUC-Ete-033167	Echinops telfairi	86.79	0.00e+00	1603.00
IUUC-Eca-033685	Equus caballus	92.35	0.00e+00	4084.00
IUUC-Fca-035647	Felis catus	91.73	0.00e+00	4110.00
IUUC-Fal-036845	Ficedula albicollis	93.41	0.00e+00	4154.00
IUUC-Gga-040959	Gallus gallus	90.77	0.00e+00	5401.00
IUUC-Gac-041349	Gasterosteus aculeatus	85.59	0.00e+00	3715.00
IUUC-Ggo-045170	Gorilla gorilla	93.05	0.00e+00	4115.00
IUUC-Hsa-046059	Homo sapiens	92.92	0.00e+00	4145.00
IUUC-Loc-052783	Lepisosteus oculatus	86.30	0.00e+00	5086.00
IUUC-Laf-053884	Loxodonta africana	88.36	0.00e+00	5234.00
IUUC-Mcc-055804	Macaca mulatta	88.27	0.00e+00	5178.00
IUUC-Mga-060008	Meleagris gallopavo	89.84	0.00e+00	5355.00
IUUC-Mmr-061081	Microcebus murinus	88.12	0.00e+00	5246.00
IUUC-Mdo-062888	Monodelphis domestica	93.84	0.00e+00	3809.00
IUUC-Mmu-063327	Mus musculus	88.30	0.00e+00	5190.00
IUUC-Mpu-066905	Mustela putorius furo	88.17	0.00e+00	5186.00
IUUC-Mlu-068215	Myotis lucifugus	89.85	0.00e+00	4061.00
IUUC-Nle-069414	Nomascus leucogenys	86.92	0.00e+00	5072.00
IUUC-Opr-070819	Ochotona princeps	88.48	0.00e+00	3988.00
IUUC-Ont-072678	Oreochromis niloticus	87.16	0.00e+00	3812.00
IUUC-Oan-072974	Ornithorhynchus anatinus	93.01	0.00e+00	4142.00
IUUC-Ocu-074919	Oryctolagus cuniculus	88.41	0.00e+00	5217.00
IUUC-Oga-088068	Otolemur garnettii	88.66	0.00e+00	5294.00
IUUC-Oar-090050	Ovis aries	89.50	0.00e+00	3986.00
IUUC-Ptr-090841	Pan troglodytes	87.63	0.00e+00	5121.00
IUUC-Psi-093088	Pelodiscus sinensis	90.53	0.00e+00	5387.00
IUUC-Pfo-097201	Poecilia formosa	75.99	0.00e+00	3379.00
IUUC-Pab-098130	Pongo abelii	87.61	0.00e+00	5117.00
IUUC-Pca-100839	Procavia capensis	83.69	0.00e+00	3515.00
IUUC-Pva-102115	Pteropus vampyrus	92.17	0.00e+00	2529.00
IUUC-Rno-105207	Rattus norvegicus	88.23	0.00e+00	5170.00
IUUC-Sha-107011	Sarcophilus harrisii	86.12	0.00e+00	4067.00
IUUC-Tgu-116970	Taeniopygia guttata	90.13	0.00e+00	5320.00
IUUC-Tru-117758	Takifugu rubripes	85.61	0.00e+00	3766.00
IUUC-Ttr-128857	Tursiops truncatus	83.00	0.00e+00	2402.00
IUUC-Xtr-131909	Xenopus tropicalis	85.78	0.00e+00	5125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence